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您的检索式：作者名="Samuel Sanchez"
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| 1 | Ionic Species Affect the Self-Propulsion of Urease-Powered Micromotors显示文摘Enzyme-powered motors self-propel through the catalysis of in situ bioavailable fuels,which makes them excellent candidates for biomedical applications.However,fundamental issues like their motion in biological fluids and the understanding of the propulsion mechanism are critical aspects to be tackled before a future application in biomedicine.Herein,we investigated the physicochemical effects of ionic species on the self-propulsion of urease-powered micromotors.Results showed that the presence of PBS,NaOH,NaCl,and HEPES reduced self-propulsion of urease-powered micromotors pointing towards iondependent mechanisms of motion.We studied the 3D motion of urease micromotors using digital holographic microscopy to rule out any motor-surface interaction as the cause of motion decay when salts are present in the media.In order to protect and minimize the negative effect of ionic species on micromotors’performance,we coated the motors with methoxypolyethylene glycol amine(mPEG)showing higher speed compared to noncoated motors at intermediate ionic concentrations.These results provide new insights into the mechanism of urease-powered micromotors,study the effect of ionic media,and contribute with potential solutions to mitigate the reduction of mobility of enzyme-powered micromotors. | Xavier Arque Xavier Andres Rafael Mestre Bernard Ciraulo Jaime Ortega Arroyo Romain Quidant Tania Patino Samuel Sanchez | 2020 | Research2020，，1： | 3 |
| 2 | Electrochemical nanobiosensors 显示文摘 | Martin Pumera Samuel Sanchez Izumi Ichinose | 2007 | Sensors and Actuators B2007，123，2： | 1 |
| 3 | Nonsteroidal anti-inflammatory drug effectivity in preventing postendoscopic retrograde cholangiopancreatography pancreatitis: A systematic review and meta-analysis显示文摘BACKGROUND Endoscopic retrograde cholangiopancreatography(ERCP)is the primary therapeutic procedure for the treatment of diseases affecting the biliary tree and pancreatic duct.Although the therapeutic success rate of ERCP is high,the procedure can cause complications,such as acute pancreatitis[post-ERCP pancreatitis(PEP)],bleeding and perforation.AIM To assess the efficacy of non-steroidal anti-inflammatory drugs(NSAIDs)in preventing PEP during follow-up.METHODS Databases such as MEDLINE,EMBASE and Cochrane Central Library were searched.Only randomized controlled trials(RCTs)comparing the efficacy of NSAIDs and placebo for the prevention of PEP were included.Outcomes evaluated included the incidence of PEP,severity of pancreatitis,route of administration,types,dose,and timing of administration of NSAIDs.RESULTS Twenty-six RCTs were considered eligible with a total of 8143 patients analyzed.Overall,4020 patients used NSAIDs before ERCP and 4123 did not use NSAIDs(control group).Ultimately,298 cases of post-ERCP acute pancreatitis were diagnosed in the NSAID group and 484 cases in the placebo group.The risk of PEP was lower in the NSAID group risk difference(RD):-0.04;95%confidence interval(CI):-0.07 to-0.03;number needed to treat(NNT),25;P<0.05.NSAID use effectively prevented mild pancreatitis compared to placebo use(2.5%vs 4.1%;95%CI:-0.05 to-0.01;NNT,33;P<0.05),but information on moderate PEP and severe PEP could not be fully elucidated.Only rectal administration reduced the incidence of PEP with RD:-0.06;95%CI:-0.08 to-0.04;NNT,17;P<0.05).Furthermore,only the use of diclofenac or indomethacin was effective in preventing PEP,at a dose of 100 mg,which must be administered before performing ERCP.CONCLUSION Rectal administration of diclofenac and indomethacin significantly reduced the risk of developing mild PEP.Additional RCTs are needed to compare the efficacy between NSAID routes of administration in preventing PEP. | Juan Pablo Román Serrano JoséJukemura Samuel Galante Romanini Paúl Fernando Guamán Aguilar Juliana Silveira Lima de Castro Isabela Trindade Torres JoséAndres Sanchez Pulla Otavio Micelli Neto Eloy Taglieri JoséCelso Ardengh | 2020 | World Journal of Gastrointestinal Endoscopy2020，12，11： | 1 |
| 4 | Determining the appropriate sleeve lobectomy versus pneumonectomy ratio in central non-small cell lung cancer patients: an audit of an aggressive policy of pneumonectomy avoidance显示文摘 | Abel Gómez-Caro Samuel Garcia Noemí Reguart Esther Cladellas Pedro Arguis Marcelo Sanchez Josep Maria Gimferrer | 2011 | European Journal of Cardio-Thoracic Surgery2011，，3： | 1 |
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