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2篇 您的检索式:作者名="Samit Kumar Nandi"
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1Macro-to-micro porousspecial bioactive glass and ceftriaxone-sulbactam composite drugdelivery system for treatment of chronic osteomyelitis : aninvestigation through in vitro and in vivo animal trial显示文摘Biswanath Kundu Samit Kumar Nandi 2011J MaterSci:Mater Med2011,22,:1
2In vitro and in vivo degradability,biocompatibility and antimicrobial characteristics of Cu added iron-manganese alloy显示文摘In recent years,iron(Fe)based degradable metal is explored as an alternative to permanent fracture fixation devices.In the present work,copper(Cu)is added in Fe-Mn system to enhance the degradation rate and antimicrobial properties.Fe-Mn-x Cu(x=0.9,5 and 10 wt.%)alloys are prepared by the meltingcasting-forging route.XRD analysis confirms austenite phase stabilization due to the presence of Mn and Cu.As predicted by Thermo-Calc calculations,Cu rich phase precipitations are noticed along the austenite grain boundaries.Degradation behaviours of Cu added Fe-Mn alloys are investigated through static immersion and electrochemical polarization where enhanced degradation is found for higher Cu added alloys.When challenged against E.Coli bacteria,the Fe-Mn-Cu alloy media extract shows a significant bactericidal effect compare to the base alloy.In vitro cytocompatibility studies,as determined using MG63 and MC3T3-E1 cell lines,indicate increased cell density as a function of time for all the alloys.When implanted in rabbit femur,the newly developed alloy does not show any kind of tissue necrosis around the implants.Better osteogenesis and higher new bone formation are observed with Fe-Mn-10 Cu alloy as evident from micro-computed tomography(μ-CT)and fluorochrome labelling.Santanu Mandal Vijay Kishore Madhuparna Bose Samit Kumar Nandi Mangal Ro 2021Journal of Materials Science & Technology2021,,25:1
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