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| 1 | Evolution of transanal total mesorectal excision for rectal cancer:From top to bottom显示文摘The gold standard for curative treatment of locally advanced rectal cancer involves radical resection with a total mesorectal excision(TME). TME is the most effective treatment strategy to reduce local recurrence and improve survival outcomes regardless of the surgical platform used. However, there are associated morbidities, functional consequences, and quality of life(QoL) issues associated with TME; these risks must be considered during the modern-day multidisciplinary treatment for rectal cancer. This has led to the development of new surgical techniques to improve patient, oncologic, and QoL outcomes. In this work, we review the evolution of TME to the transanal total mesorectal excision(TaTME) through more traditional minimally invasive platforms. The review the development, safety and feasibility, proposed benefits and risks of the procedure, implementation and education models, and future direction for research and implementation of the TaTME in colorectal surgery. While satisfactory short-term results have been reported, the procedure is in its infancy, and long term outcomes and definitive results from controlled trials are pending.As evidence for safety and feasibility accumulates,structured training programs to standardize teaching,training, and safe expansion will aid the safe spread of the TaTME. | Sameh Hany Emile F Borja de Lacy Deborah Susan Keller Beatriz Martin-Perez Sadir Alrawi Antonio M Lacy Manish Chand | 2018 | World Journal of Gastrointestinal Surgery2018，10，3： | 18 |
| 2 | Liver stiffness as a predictor of hepatocellular carcinoma behavior in patients with hepatitis C related liver cirrhosis显示文摘Background: Risk strati cation and prognostication of hepatocellular carcinoma (HCC) help to improve patient outcome. Herein we investigated the role of liver stiffness measurement (LSM) in the prediction of HCC behavior. Methods: Totally 121 na ve patients with HCC were included. HCC radiological evaluation and staging were done. LSM was measured using virtual touch quanti cation. Patients were divided into early to intermediate HCC (BCLC-0, A and B) and late HCC (BCLCC and D). HCC was treated according to the BCLC stage. HCC recurrence-free interval was estimated. Results: The mean LSM inside the tumor was signi cantly lower than the peri-tumoral area and the cirrhotic non-cancerous liver parts (P<0.001). In late HCCs stage, the mean LSM inside the tumor and in the peri-tumoral tissue was lower than the corresponding values in the early to intermediate HCCs stage (P<0.001). LSM inside the tumor and in the peri-tumoral tissue negatively correlated with serum AFP, tumor vascular invasion, and stage (P<0.05). The recurrence-free interval was directly correlated to LSM inside the tumor and inversely to LSM in cirrhotic non tumorous liver part. Kaplan-Meier analysis showed that the recurrence-free interval was signi cantly longer in patients with LSM inside the tumor of ≥1.25m/s compared to those with LSM inside the tumor of<1.25m/s. Conclusions: LSM can serve as a potential non-invasive predictor for HCC clinical behavior and the recurrence-free interval following loco-regional treatments. | Sameh A Lashen Mohamed M Elshafei Fahmy H Hablass Eman A Alsayed Asmaa A Hassan | 2020 | Hepatobiliary & Pancreatic Diseases International2020，19，1： | 4 |
| 3 | Efficacy and safety of botulinum toxin in treatment of anismus: A systematic review显示文摘AIM: To evaluate the efficacy and safety of botulinum toxin type A(BTX-A) in the management of patients with anismus. METHODS: An organized search of published literature was conducted using electronic databases including: Pub Med/MEDLINE, and Cochrane Central Register of Control ed Trials, also an internet-based search using 'Google Scholar' service was conducted. Both comparative and observational studies were included. We excluded irrelevant articles, editorials, case reports, reviews, and meta-analyses. The studies that followed the patients less than 6 mo were excluded. Variables collected were demographic data of the patients, technique of BTX-A injection and number of sessions, short-term and longterm clinical improvement, post-injection changes in electromyography(EMG), defecography, manometry, and balloon expulsion test, and complications recorded after BTX-A injection.RESULTS: Seven studies comprising 189 patients were included in the review. The median age of the patients was 41.2 years and female-to-male ratio was 1.3:1. The median dose of BTX-A injected per procedure was 100 IU(range, 20-100 IU). Lateral injection was done in five trails and combined lateral and posterior injections in two trials. Three studies used endorectal ultrasonographyguided technique, one study used EMG-guided technique,whereas the remaining three studies used manual palpation with the index finger. The median percentage of patients who reported initial improvement of symptoms was 77.4%(range 37.5%-86.7%), this percentage declined to a median of 46%(range 25%-100%) at 4 mo after injection of BTX-A. Rates of improvement evaluated by balloon expulsion test, EMG, and defecography ranged between(37.5%-80%),(54%-86.7%), and(25%-86.6%), respectively. Fourteen(7.4%) patients developed complications after injection of BTX-A. Complication rates across the studies ranged from 0% to 22.6%. CONCLUSION: Initial satisfactory improvement of symptoms after BTX-A injection remarkably deteriorated after 3 mo of the procedure. However, repeated injection may provide better sustained results with no additional morbidities. Further analysis of more patients is necessary to conclude the safety of BTX-A for the treatment of anismus. | Sameh Hany Emile Hossam Ayman Elfeki Hosam Ghazy Elbanna Mohamed Youssef Waleed Thabet Tito M Abd El-Hamed Basem Said Ahmed Lotfy | 2016 | World Journal of Gastrointestinal Pharmacology and Therapeutics2016，7，3： | 3 |
| 4 | A Modified fuzzy C-means algorithm for bias field Estimation and Segmentation of MRI data显示文摘 | Mohamed N Ahmed Sameh M Yamany Nevin Mohamed | 2002 | IEEE trans on Medical Imaging2002，21，3： | 1 |
| 5 | Two-mode over- constrained three-DOFs rotational-translational linear-motor-based parallel-kinematics mechanism for machine tool applications 显示文摘 | Sameh R HervJacques M Saeid N Hieul T | 2007 | Robotiea2007，25，4： | 1 |
| 6 | Waveform se- lection in radar target classification 显示文摘 | Sameh M Sowelam Ahmed H Tewfik | 2000 | IEEE trans- action on information theory2000，46，3： | 1 |
| 7 | A modified fuzzy C-Means algorithm for bias field estimation and segmentation of MRI data显示文摘 | Mohamed N Ahmed Sameh M Yamany Nevin Mohamed | 2002 | IEEE Transactions on Medical Imaging2002，21，3： | 1 |
| 8 | A Modified Fuzzy C-Means Algorithm for Bias Field Estimation and Sregqnentation of MRI Data 显示文摘 | Mohamed N Ahmed Sameh M Yamany Nevin Mohmncd | 2002 | IEEE Transaclions on Medical Imaging2002，21，3： | 1 |
| 9 | Different techniques of transconjunctival cannulated vitrectomy versus conventional non-cannulated vitrectomy in various vitreoretinal disorders显示文摘 | Amin Faisal Ellakwa Sameh M Elgouhary Hammouda Ghoraba | 2013 | Clinical Ophthalmology (default)2013，，： | 1 |
| 10 | A Fuzzy Hyperspectral Classifier for Automatic Target Recognition(ATR) Systems显示文摘 | M Sameh Yamanu A Aly Farag Shin-Yi Hsu | 1999 | Pattern Recognition Letters1999，20，： | 1 |
| 11 | A modified fuzzy C-means algorithm for bias field estimation and segmentation of MRI data显示文摘 | MOHAMED N A SAMEH M Y NEVIN M | 2002 | IEEE Frans On Medical Imaging2002，21，3： | 1 |
| 12 | Evaluation of isolated starter lactic acid bacteria in Ras cheese ripening and flavour development显示文摘 | Sameh A Nour A El S M | | 0，，03： | 1 |
| 13 | A Modified Fuzzy C-Means Algorithm for Bias Field Estimation and Segmentation of MRI Data显示文摘 | Mohamed N Ahmed Sameh M Yamany Nevin Mhohamed | 2002 | IEEE TRANSACTIONS ON MEDICAL IMAGING2002，21，3： | 1 |
| 14 | Abouel-Seoud, Noise generating mechanisms of vehicle al- ternators显示文摘 | Nabil Hammad Sameh M Metwalley Abou-E1-Nour | 2005 | SAKE2005，，： | 1 |
| 15 | Preconditioning techniques for nonsymmetric linear systems in the computation of incompressible flows 显示文摘 | Manguoglu M Sameh A H Saied F | 2009 | Journal of Applied Mechanics2009，76，2： | 1 |
| 16 | Potato peel as feed- stock for bioethanol production: A comparison of acidic and enzymatic hydrolysis 显示文摘 | Khawla B J Sameh M Imen G | 2014 | Industrial Crops and Prod- ucts2014，52，： | 1 |
| 17 | Float Consumption Impact on Cost and Schedule in the Construction Industry显示文摘 | Sakka I Zafer EI-Sayegh M Sameh | 2007 | Journal of Construction Engineering and Management2007，133，2： | 1 |
| 18 | Hydroconversion of cyclohexene using H-ZSM-5 zeolite catalysts promoted via hydrochlorination and/or platinum incorporation显示文摘 | Ahmed K Aboul-Gheit Sameh M Aboul-F'otouh | 2006 | Journal of Molecular Catalysis A:Chemical2006，245，12： | 1 |
| 19 | Performance models for the Spike banded linear system solver显示文摘 | Manguoglu M Saied F Sameh A Grama A | 2011 | Scientific Programming2011，19，1： | 1 |
| 20 | Argon laser iridoplasty in the treatment of plateau-like iris configuration as result of numerous ciliary body cysts显示文摘 | Jonathan GC Felipe AM Sameh M | 2005 | Am J Ophthalmol2005，139，： | 1 |
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