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1篇 您的检索式:作者名="Samadhan P.Pawar"
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1CdS nanocrystals as fluorescent probe for detection of dolasetron mesylate in aqueous solution:Application to biomedical analysis显示文摘A simple and straightforward method for the determination of dolasetron mesylate(DM) in aqueous solution was developed based on the fluorescence quenching of 3-Mercaptopropionic acid(MPA) capped Cd S quantum dots(QDs).The structure,morphology,and optical properties of synthesized QDs were characterized by using UV-Vis absorption spectroscopy,fluorescence spectroscopy,transmission electron microscopy(TEM) and dynamic light scattering(DLS) measurements.Under the optimum conditions,the MPA-Cd S QDs fluorescence probe offered good sensitivity and selectivity for detecting DM.The probe provided a highly specific selectivity and a linear detection of DM in the range of 2–40 μg/m L with detection limit(LOD) 1.512 μg/m L.The common excipients did not interfere in the proposed method.The fluorescence quenching mechanism of Cd S QDs is also discussed.The developed sensor was applied to the quantification of DM in urine and human serum sample with satisfactory results.Samadhan P.Pawar Laxman S.Walekar Uttam R.Kondekar Dattatray B.Gunjal Anil H.Gore Prashant V.Anbhule Shivajirao R.Patil Govind B.Kolekar 2016Journal of Pharmaceutical Analysis2016,6,6:0
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