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| 1 | 食物蛋白诱导性小肠结肠炎综合征:一项基于澳大利
亚普通人群的研究,2012-2014显示文摘背景 食物蛋白诱导性小肠结肠炎综合征(FPIES)是一种非IgE 介导的胃肠道过敏性疾病。基于大规模人群的FPIES 流行病学调查尚无报道。目的 本文拟明确澳大利亚婴幼儿中FPIES 的发病率和临床特点。方法 2012 至2014年通过澳大利亚儿科监测体系开展了一项全国范围内的调查,由1 400 名儿科医生每月上报2 岁以下的婴幼儿中诊为急性FPIES 的新病例。结果 230 例患儿被诊为FPIES。FPIES 在澳大利亚2 岁以下儿童中的发病率为15.4/(10 万·年)。首次发作、诊断及上报的中位数年龄分别为5、7 和10 月龄。发病没有性别倾向性。7% 的患儿有兄弟姐妹也患有FPIES,5% 在纯母乳喂养期间发病。68 例患儿仅对单种食物过敏(20% 对2 种食物过敏,12% 对3 种以上食物过敏)。最常见的FPIES 诱因是大米(45%)、牛奶(33%)以及鸡蛋(12%)。51% 的患儿在首次暴露时即有过敏反应。与单种食物过敏相比,多种食物过敏者的首次发病年龄更小(均数分别为4.6 和5.8 月龄,P = 0.001),更容易有水果或蔬菜过敏(P < 0.000 1)。纯母乳喂养4 个月以上的婴儿更不易发生多种食物过敏性FPIES(P = 0.06)。对包括牛奶在内的多种食物过敏的FPIES 患儿中64% 同时对固体食物过敏。42% 鱼类过敏性FPIES 患儿并发其他食物过敏。结论 FPIES并不罕见,估计发病率为15.4/(10 万·年)。大米是澳大利亚最常见的食物诱因。与多重食物过敏性FPIES 相关的危
险因素包括早期起病、对水果或蔬菜不能耐受。 | Sam Mehr FRACP, Katie Frith FRACP Elizabeth H. Barnes BAppSc MStat and Dianne E Campbell | 2018 | 中华临床免疫和变态反应杂志2018，12，1： | 2 |
| 2 | Quantitative trait loci controlling sulfur containing amino acids,methionine and cysteine,in soybean seeds显示文摘 | Panthee D R Pantalone V R Sams C E | 2006 | Theoretical and Applied Genetics2006，112，： | 1 |
| 3 | Seed quality QTL in a prominent soybean population显示文摘 | Hyten D L Pantalone V R Sams C E | 2004 | Theor App Genet2004，109，： | 1 |
| 4 | The effect of postharvest infiltration of calcium, magnesium, or strontium on decay, firmness, respiration and ethylene production in apples显示文摘 | Conway W S Sams C E | 1987 | J Amer Soc Hort Sci1987，112，： | 1 |
| 5 | Quantitative trait loci controlling sulfur contsining amino acids,methionine and cysteine,in soybean seeds显示文摘 | Panthee D R Pantalone V R Sams C E | 2005 | Theor App Genet2005，112，： | 1 |
| 6 | Intrahepatic cholestasis of pregnancy in women with a multiple pregnancy : an analysis of risks and pregnancy outcomes 显示文摘 | Lausman AY A1-Yaseen E Sam D | 2008 | J Obstet Gynaecol Can2008，30，11： | 1 |
| 7 | Self cleaning photoactive TiO2 coatings on SLS glasses by sol-gel dip coating显示文摘 | Sam E D Urgen M Tepehan F Z Gunay V | 2004 | Key Engineering Materials2004，，： | 1 |
| 8 | Pre-and postharvest calcium treatment of apple fruit and its effect on quality显示文摘 | Conway W S Sams C E Hickey K D | 2002 | Acta Horticulturae2002，594，： | 1 |
| 9 | The integration of Dow's fire and explosion index (F&EI) into process design and optimization to achieve inherently safer design显示文摘 | UARDIN J SAM MANNAN M MAHMOUD E | 2007 | Loss Prevention in the Process Industries2007，20，： | 1 |
| 10 | Quantitative trait loci for β-conglycinin (7S) and glycinin (11S) fractions of soybean storage protein显示文摘 | Panthee D R Kwanyuen P Sams C E | 2004 | Journal of the American Oil Chemists'' Society2004，81，： | 1 |
| 11 | Fracture strengths of provisional restorations reinforced with plasms treated woven polyethylene fiber显示文摘 | Sam adzadeh A Kugel G Hurley E | 2000 | J Prothet Dent2000，81，4： | 1 |
| 12 | Effects of beta-adrebergic receptor blockers on cardiac function:a comparative study in male versus femalerats显示文摘 | Tuncay E Seymen AA Sam P | 2009 | Can J Physiol Pharmacol2009，87，4： | 1 |
| 13 | Magnesium science,technology and applications显示文摘 | Eliezer D Aghion E (SAM)Froes F H | 1998 | Advanced Performance Materials1998，5，： | 1 |
| 14 | Aquaporin-1 expression is decreased in human and mouse corneal endothelial dysfunction显示文摘 | Macnamara E Sams GW Smith K | 2004 | Mol Vis2004，10，： | 1 |
| 15 | Aptamer-mediated inhibition of Mycobacterium tuberculosis polyphosphate kinase 2显示文摘 | Shum K T Lui E L Wong S C Yeung P Sam L Wang Y | | 0，，： | 1 |
| 16 | Eeffect of Calcium Infiltration on EthyleneProduction,Respiration Rats,Soluble Polyuronide Content and Quality of 'Golden Delicious'Apple Fruit显示文摘 | E Carl Sams S Williams | 1984 | J Amer Soc Hort Sci1984，109，1： | 1 |
| 17 | Seed quality QTL in a prominent soybean population显示文摘 | Hyten D L Pantalone V R Sams C E | 2004 | Theoretical and Applied ( enet- ies2004，109，： | 1 |
| 18 | Hydraulic conductance and water potential gradients in squash leaves showing mycorrhizainduced increases in stomatal conductance显示文摘 | AUGER M TOLER H D SAMS C E | 2008 | Mycorrhiza2008，，18： | 1 |
| 19 | Timing and special concerns regarding endocrine surgery during pregnancy显示文摘 | Sam S Molitch M E | 2003 | Endocrinol Metab Clin North Am2003，32，2： | 1 |
| 20 | Experiences with landslide instru- mentation in the southeast显示文摘 | Tice J A Sams C E | 1974 | Transportation Research Record1974，482，： | 1 |
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