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| 1 | The emergence of drug resistant HIV variants and novel anti-retroviral therapy显示文摘After its identification in 1980s,HIV has infected more than 30 million people worldwide.Inthe era of highly active anti-retroviral therapy,anti-retroviral drug resistance results frominsufficient anti-retroviral pressure,which may lead to treatment failure.Preliminary studiessupport the idea that anti-retroviral drug resistance has evolved largely as a result of low-adherence of patients to therapy and extensive use of anti-retroviral drugs in the developedworld;however,a highly heterogeneous horde of viral quasi-species are currently circulating indeveloping nations.Thus,the prioritizing of strategies adopted in such two worlds should be quitedifferent considering the varying anti-retroviral drug resistance prevalence.In this article,weexplore differences in anti-retroviral drug resistance patterns between developed and developingcountries,as they represent two distinct ecological niches of HIV from an evolutionary standpoint. | Koosha Paydary Parisa Khaghani Sahra Emamzadeh-Fard Seyed Ahmad Seyed Alinaghi Kazem Baesi | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，7： | 5 |
| 2 | Prevalence survey of infection with Treponema pallidum among HIV-positive patients in Tehran显示文摘Objective:To identify the frequency of syphilis among Iranian HIV-positive patients.Methods:A cross-sectional study on the prevalence of syphilis and HIV co-infection among 450 patients diagnosed with HIV infection was conducted between 2004 and 2008 at Imam Khomeini hospital,Tehran,Iran.The lab tests including CD4 cell count,cerebrospinal fluid,veneral disease research laboratory(VDRL),fluorescent treponema antibody-absorption(FTA-Abs)and viral load were performed for all the patients.Data regarding medical history and their demographics were also collected.Results:Of all 450 HIV-positive patients,24(5.3%)had a positive VDRL test and only two men had a FTA-Abs positive test which means 0.45%of them had a definite co-infection of syphilis.65.3%of the HIV-positive patients were injection drug users that the co-infection prevalence of them was 0.7%.We did not find any patient with neurosyphilis.Conclusions:Considering the increasing prevalence of HIV and also extensive use of highly active antiretroviral therapy in developing nations,the diagnosis of syphilis should be timely established using screening tests among such patients. | Banafsheh Moradmand Badie Zeinab Yavari Shooka Esmaeeli Koosha Paydary Sahra Emamzadeh-Fard SeyedAhmad SeyedAlinaghi Mehrnaz Rasoulinejad | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，4： | 3 |
| 3 | Structural health monitoring of bridges using wireless sensor networks显示文摘 | Harms Tyler Sedigh Sahra Bastianini Filippo | 2010 | Instrumentation&Measurement Magazine IEEE2010，13，6： | 1 |
| 4 | The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level 显示文摘 | Ben Sahra I Laurent K | 2008 | Oncogene2008，27，25： | 1 |
| 5 | The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a de- crease of cyclin D1 level 显示文摘 | Sahra I Laurent K Loubat A | 2008 | Oncogene2008，2，7： | 1 |
| 6 | Metformin,independent of AMPK, induces mTOR inhibition and cell-cyclearrest through REDD1 显示文摘 | Ben Sahra I Regazzetti C Robert G | 2011 | Cancer Res2011，71，13： | 1 |
| 7 | Metformin, independent of AMPK, induces roTOR inhibition and cell-cycle arrest through REDD 1 显示文摘 | Ben Sahra I Regazzetti C Robert G | 2011 | Cancer Ptes2011，71，13： | 1 |
| 8 | The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 levell显示文摘 | Ben Sahra I Laurent K Loubat A | | 0，，25： | 1 |
| 9 | The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level显示文摘 | Ben Sahra I Laurent K Loubat A | 2008 | Oncogene2008，27，25： | 1 |
| 10 | Metformin in cancer therapy: a new perspective for an old antidiabetic drug显示文摘 | Ben Sahra I Ire Marchand-Brustel Y Tanti J F | 2010 | Mol Cancer Ther2010，9，5： | 1 |
| 11 | The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin DI level显示文摘 | Ben Sahra I Laurent K Loubat A | 2008 | Oncogene2008，27，25： | 1 |
| 12 | The antidiabetic drug mefformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level显示文摘 | Ben Sahra I Laurent K Loubat A | 2008 | Oncogene2008，27，25： | 1 |
| 13 | Metfonnin in cancer therapy: a new perspective for an old antidiabetic drug显示文摘 | Ben Sahra I Le Marchand-Brustel Y TantiJF | 2010 | Mol Cancer Ther2010，9，5： | 1 |
| 14 | The antidiabetic drug Metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level显示文摘 | Sahra IB Laurent K Loubat A | 2008 | Oncogene2008，27，： | 1 |
| 15 | The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level显示文摘 | Ben Sahra I Laurent K Loubat A | 2008 | Oncogene2008，27，25： | 1 |
| 16 | Acadesine kills chronic myelogenous leukemia (CML) cells through PKC-dependent induction of autophagic cell death显示文摘 | Robert G Ben Sahra I Puissant A | | 0，，： | 1 |
| 17 | The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease ofcyclin D1 level显示文摘 | Ben Sahra I Laurent K Loubat A | 2008 | Oneogene2008，27，25： | 1 |
| 18 | Metformin in cancer therapy:a new perspective for an old antidiabetic drug显示文摘 | Ben Sahra I Le Marchand-Brustel Y Tanti JF | 2010 | Mol Cancer Ther2010，9，5： | 1 |
| 19 | The antidiahetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level 显示文摘 | Ben Sahra I Laurent K Loubat A | 2008 | Oncogene2008，27，25： | 1 |
| 20 | Targeting cancer cell metabolism:the combination of metformin and 2-deoxyglucose induces p53-dependent apoptosis in prostate cancer cells显示文摘 | Ben Sahra I Laurent I Giuliano K | | 0，，6： | 1 |
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