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| 1 | Serum bicarbonate may independently predict acute kidney injury in critically ill patients:An observational study显示文摘AIM: To explore whether serum bicarbonate at admission to intensive care unit(ICU) predicted development of acute kidney injury(AKI).METHODS:We studied all patients admitted to our ICU over a 2 year period(February 2010 to 2012).The ICU has a case mix of medical and surgical patients excluding cardiac surgical,trauma and neurosurgical patients.We analysed 2035 consecutive patients admitted to ICU during the study period.Data were collected by two investigators independently and in duplicate using a standardised spread sheet to ensure accuracy.Ambiguous data were checked for accuracy where indicated.AKI was defined using the Kidney Disease Improving Global Outcomes criteria.Patients were divided into two groups;patients who developed AKI or those who did not,in order to compare the baseline characteristics,and laboratory and physiologic data of the two cohorts.Regression analysis was used to identify if serum bicarbonate on admission predicted the development of AKI.RESULTS:Of 2036 patients 152(7.5%)were excluded due to missing data.AKI developed in 43.1%of the patients.The AKI group,compared to the nonAKI group,was sicker based on their lower systolic,diastolic and mean arterial pressures and a higher acutephysiology and chronic health evaluation(APACHE)Ⅲand SAPSⅡscores.Moreover,patients who developed AKI had more co-morbidities and a higher proportion of patients who developed AKI required mechanical ventilation.The multi-regression analysis of independent variables showed that serum bicarbonate on admission(OR=0.821;95%CI:0.796-0.846;P<0.0001),APACHEⅢ(OR=1.011;95%CI:1.007-1.015;P<0.0001),age(OR=1.016;95%CI:1.008-1.024;P<0.0001)and presence of sepsis at ICU admission(OR=2.819;95%CI:2.122-23.744;P=0.004)were each significant independent predictors of AKI.The area under the ROC curve was 0.8(95%CI:0.78-0.83),thereby demonstrating that the predictive model has relatively good discriminating power for predicting AKI.CONCLUSION:Serum bicarbonate on admission may independently be used to make a diagnosis of AKI. | Anuksha Gujadhur Ravindranath Tiruvoipati Elizabeth Cole Saada Malouf Erum Sahid Ansari Kim Wong | 2015 | World Journal of Critical Care Medicine2015，4，1： | 3 |
| 2 | Determination of the herbicide flurox- ypyr in oil matrices显示文摘 | Muhamad H B Ai T Y Sahid I B | 2008 | Journal of Environmental Science and Health Part B-Pesticides Food Contaminants and Agricultural Wastes2008，43，2： | 1 |
| 3 | Allelopathic effect of Lantana (Lantana-Camara) and Siam weed (Chromolaena odorata) on selected crops显示文摘 | Sahid I B Sugau J B | 1993 | Weed Science1993，41，： | 1 |
| 4 | Study on resistant biotypes of Echinochloa crus-galli in Malaysia 显示文摘 | Rahman M M Bin Sahid 1 Juraimi A S | 2010 | Australian Journal of Crop Science2010，4，2： | 1 |
| 5 | Design of power stage and controller for DC-DC converter systems using PSPICE显示文摘 | MUHAMAD N D SAHID M R YATIM A H M | 2005 | Power Electronics and Drives Systems2005，，2： | 1 |
| 6 | Effect of oral glucocorticoid treatment on serum inflammatory markers in acute asthma 显示文摘 | Sahid EA Hogg CL Bungre JK | 2000 | Arch Dis Child2000，83，2： | 1 |
| 7 | Downward movement of chlorpyrifos in the soil of an oil palm plantation in sepang, Selangor, Malaysia显示文摘 | Muhamad H Ai T Y Sahid I | 2010 | Journal of Oil Palm Research2010，22，1： | 1 |
| 8 | Pesticide risk assess- ment:A study on inhalation and dermal exposure to 2,4-D and paraquat among Malaysian paddy farmers 显示文摘 | Baharuddin MR Sahid IB Noor MA | 2011 | J Environ Sci Health B2011，46，7： | 1 |
| 9 | Two novel point mutations localized upstream and downstream of the HMG box region of the SRY gene in three Indian 46,XY females with sex reversal and gonadal tumour formation显示文摘 | Sahid M Dhillion VS Jain N | 2004 | Mol Hum Reprod2004，10，7： | 1 |
| 10 | Cyclooxygenase-2 Inhibitors Suppress the Growth of Human Hepatocellular Carcinoma Implants in NudeMice显示文摘 | Michaelak Mirjams Sahid | 2004 | Carcinogenesis2004，25，7： | 1 |
| 11 | Effect of oral glucocorticoid treatment on serum inflammatory markers in acute asthma显示文摘 | Sahid El-Radhi A Hogg CL Bungre JK | 2000 | Arch Dis Child2000，83，： | 1 |
| 12 | Effect of oral glucocorticoid treatment on serum inflammatory markers in acute asthma显示文摘 | Sahid El-Radhi A Hogg CL Bungre JK | 2000 | Arch Dis Child2000，83，2： | 1 |
| 13 | Pesticide risk assessment:a study on inhalation and dermal exposure to 2,4-D and paraquat among Malaysian paddy farmers显示文摘 | Baharuddin MR Sahid IB Noor MA | | 0，，： | 1 |
| 14 | The Impulsivity and Drinking Motives as Predictor of the Alcohol Consumption in College Students显示文摘 | Diana Betancourt Ocampo Sahid Rafael Garcia Campos Jazmin Garcia Zarate Laura Alejandra Corona Guevara Alejandro Gonzalez-Gonzfilez | 2014 | Psychology Research2014，4，1： | 1 |
| 15 | Downward movement of chlorpyrifos in the soil of an oil palm plantation in sepang,Selangor, Malaysia 显示文摘 | Muhamad H Ai T Y Sahid I | 2010 | Journal of Oil Palm Re- search2010，22，： | 1 |
| 16 | Effect of oral glucocorticoid treatment on serum inflammatory markers in acute asthma显示文摘 | Sahid El Radhi A Hogg C L Bungre J K | 2000 | Arch Dis Child2000，83，2： | 1 |
| 17 | Speciationand Availability of Heavy Metals On Serpentinized Paddy Soiland Paddy Tissue 显示文摘 | Roslaili Abdul Aziz Sahibin Abd Rahim Ismail Sahid etc | 2015 | Procedia - Social and Behavioral Sciences2015，，195： | 1 |
| 18 | Design of power stage and controller for DC-DC converter systems using PSPICE 显示文摘 | MUHAMAD N D SAHID M R YATIM A H M | 2005 | Power Electronics and Drives Systems2005，，2： | 1 |
| 19 | Downward movement of chlorpyrifos in the soil of an oil palm plantation in Sepang, Se- langor, Malaysia显示文摘 | Muhamad H Ai T Y Sahid I | 2010 | Journal of Oil Palm Research2010，22，： | 1 |
| 20 | Effect of oral glucocor- ticoid treatment on serum inflammatory markers in acute asthma 显示文摘 | A Sahid E1-Radhi Claire L Hogg etal | 2000 | Arch Dis Child2000，83，： | 1 |
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