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| 1 | Biomarkers for hepatocellular cancer显示文摘Hepatocellular carcinoma(HCC)is the third leading cause of cancer-related deaths worldwide.If diagnosed early,curative treatment options such as surgical resection,loco-regional therapies,and liver transplantation are available to patients,increasing their chances of survival and improving their quality of life.Unfortunately,most patients are diagnosed with late stage HCC where only palliative treatment is available.Therefore,biomarkers which could detect HCC early with a high degree of sensitivity and specificity,may play a crucial role in the diagnosis and management of the disease.This review will aim to provide an overview of the different biomarkers of HCC comprising those used in the diagnosis of HCC in at risk populations,as well as others with potential for prognosis,risk predisposition and prediction of response to therapeutic intervention. | Gurjot Singh Eric M Yoshida Sahaj Rathi Vladimir Marquez Peter Kim Siegfried R Erb Baljinder S Salh | 2020 | World Journal of Hepatology2020，12，9： | 1 |
| 2 | Extrapulmonary small cell carcinoma of lymph node: Pooled analysis of all reported cases显示文摘AIM: To study clinical outcomes and management of lymph nodes extrapulmonary small cell carcinoma(LNEPSCC). METHODS: Herein, we perform a systematic search of published literature in the PubMed and EMBASE databases for studies describing LNEPSCC. For uniformity of reporting, LNEPSCC was staged as limited if it involved either single lymph node station or if surgery with curative intent had been undertaken. The disease was staged extensive if it involved two or more lymph node regions.RESULTS: The systematic literature review yielded eight descriptions(n = 14) involving cervical, submandibular and inguinal lymph nodes. Eleven(64.7%) patients had limited disease(LD) and six(35.3%) had extensive disease(ED) at presentation. Chemotherapy(n = 6, 35.3%) or surgery(n = 4, 23.5%) were the most common form of treatment given to these patients. Complete response was achieved in 12(70.6%) of the patients. Median(interquartile range) progression free survival and overall survival was 15(7-42) mo and 22(12.75-42) mo respectively. Of the three illustrative cases, two patients each had ED at presentation and achieved complete remission with platinum based combination chemotherapy.CONCLUSION: LNEPSCC is a rare disease with less than 15 reported cases in world literature. Surgical resection with curative intent is feasible in those with LD while platinum based combination chemoradiation is associated with favorable outcomes in patients with ED. Prognosis of LNEPSCC is better than that of small cell lung cancer in general. | Inderpaul Singh Sehgal Harpreet Kaur Sahajal Dhooria Amanjit Bal Nalini Gupta Digambar Behera Navneet Singh | 2016 | World Journal of Clinical Oncology2016，7，3： | 1 |
| 3 | A simulation study on optimal IMC based PI/PID controller for mean arterial blood pressure显示文摘 | Sahaj Saxena Yogesh V. Hote | 2012 | Biomedical Engineering Letters2012，，4： | 1 |
| 4 | Areview of arsenic poisoning and its effects on human health显示文摘 | SahaJ C Dikshit AK Bamdyophyayn et a1 | | 0，，： | 1 |
| 5 | 横荡激励下矩形缩比罐中的液体晃动力学显示文摘The present paper presents the sloshing oscillation behaviour and sloshing force in three different tanks of model scales of 1:86,1:57 and 1:43.The rectangular tank is mounted on shake table,to study the scale effect of sloshing with sway excited motion.The tests are carried out for the aspect ratio(hs/l,where hs liquid depth and l is the length of the tank)of 0.1625,0.325,and 0.4875 which represents 25%,50%and 75%of liquid fill levels,respectively.Seventeen excitation frequencies ranging from 0.4566 Hz to 1.9757 Hz are considered,which covers up to the fifth sloshing mode.The sloshing oscillations occurs in the longitudinal axis when subjected to sway excitations.An experimental setup is designed and devised to measure sloshing force by the concept of ballast mass.The inertia forces are measured by load cells and sloshing oscillation time histories are measured by capacitance probes.It is found that violent sloshing is experienced for 50%filled condition irrespective of scaled tanks,excitation amplitudes and excitation frequencies.The sloshing force is maximum in 1:43 scaled tank than other scaled sloshing tanks irrespective of the excitation frequency and amplitude for 50%fill level.Based on the experimental observations and analysis of results,it is concluded that proportionate volume of water and tank size decides the severity of sloshing in the partially filled tanks. | Sahaj K V Shwetha Shri Nasar T | 2023 | 哈尔滨工程大学学报(英文版)2023，22，2： | 0 |
| 6 | Knowledge,attitude,and practice regarding COVID-19 among COVID-19 patients and their correlation with the outcomes:A cross-sectional study显示文摘Objective:To assess the knowledge,attitude,and practice(KAP)regarding COVID-19 among COVID-19 patients and their relation with the outcomes.Methods:This cross-sectional study was carried out among COVID-19 patients(18-year-old or older)consecutively admitted to a dedicated COVID-19 hospital located in northwest Rajasthan,India.Data regarding socio-demographic parameters,KAP,and primary composite outcome(admission to intensive care unit,mechanical ventilation,or in-hospital death)were collected.KAP scores were compared between different demographic variables and primary composite outcomes.Association between different demographic variables,primary composite outcomes,and KAP scores were determined through multivariate linear regression.Besides,the correlation among KAP scores was analyzed.Results:Out of the total 222 patients,most of them(65.76%)had average KAP scores towards COVID-19.The mean scores for knowledge were 7.88,with an overall correct rate of 71.63%;the mean attitude scores were 2.42,with an overall correct rate of 60.50%;the mean practice scores were 5.12,with an overall correct rate of 64.00%.Patients who met the primary composite outcomes had higher knowledge scores,but lower attitude and practice scores.The result showed a significant positive correlation between the level of education,socioeconomic class,and knowledge,attitude,and practice towards COVID-19.Knowledge towards COVID-19 was significantly associated with a positive attitude and good practice.Conclusions:Our findings show that adult COVID-19 patients have average KAP towards COVID-19 among COVID-19 patients.Poor attitude and practice towards COVID-19 are associated with adverse outcomes,so it is suggested to strengthen attitude and practice towards COVID-19 to improve the outcomes. | Hardeva Ram Nehara Kritika Khanna Atma Ram Chhimpa Sahaj Agrawal Avadusidda Arakeri Pramendra Sirohi | 2021 | Journal of Acute Disease2021，10，4： | 0 |
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