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| 1 | Processing of porous ceramics显示文摘 | Saggio W Scott J Minnear W P | 1992 | J Am Ceram Soc Bull1992，71，11： | 2 |
| 2 | Chemoimmunotherapy in the treatment of metastatic gastric cancer显示文摘 | Recchia F Saggio G Candeloro G | 2007 | Anticancer Drugs2007，18，5： | 1 |
| 3 | CNTF variants with increased biological potency and receptor selectivity define a functional site of receptor interaction显示文摘 | Saggio I Gloaguen I Poiana G | 1995 | EMBO1995，14，13： | 1 |
| 4 | Gsα^(R201C)and estrogen reveal different subsets of bone marrow adiponectin expressing osteogenic cells显示文摘The Gsα/cAMP signaling pathway mediates the effect of a variety of hormones and factors that regulate the homeostasis of the post-natal skeleton.Hence,the dysregulated activity of Gsαdue to gain-of-function mutations (R201C/R201H)results in severe architectural and functional derangements of the entire bone/bone marrow organ.While the consequences of gain-of-function mutations of Gsαhave been extensively investigated in osteoblasts and in bone marrow osteoprogenitor cells at various differentiation stages,their effect in adipogenically-committed bone marrow stromal cells has remained unaddressed.We generated a mouse model with expression of Gsα^(R201C) driven by the Adiponectin(Adq)promoter.Adq-Gsα^(R201C) mice developed a complex combination of metaphyseal,diaphyseal and cortical bone changes.In the metaphysis,Gsα^(R201C) caused an early phase of bone resorption followed by bone deposition.Metaphyseal bone formation was sustained by cells that were traced by Adq-Cre and eventually resulted in a high trabecular bone mass phenotype.In the diaphysis,Gsα^(R201C),in combination with estrogen,triggered the osteogenic activity of Adq-Cre-targeted perivascular bone marrow stromal cells leading to intramedullary bone formation.Finally,consistent with the previously unnoticed presence of Adq-Cre-marked pericytes in intraosseous blood vessels,Gsα^(R201C) caused the development of a lytic phenotype that affected both cortical(increased porosity)and trabecular(tunneling resorption)bone.These results provide the first evidence that the Adq-cell network in the skeleton not only regulates bone resorption but also contributes to bone formation,and that the Gsα/cAMP pathway is a major modulator of both functions. | Biagio Palmisano Rossella Labella Samantha Donsante Cristina Remoli Emanuela Spica Ilenia Coletta Giorgia Farinacci Michele Dello Spedale Venti Isabella Saggio Marta Serafini Pamela Gehron Robey Alessandro Corsi Mara Riminucci | 2022 | Bone Research2022，10，4： | 1 |
| 5 | Muhicentre phase lI study of bifractionated CPT-I 1 with bimonthly leucovorin and 5-fluorouracil in patients with metastatic colorectal cancer pretreated with FOLFOX显示文摘 | Recchia F Saggio G Nuzzo A | 2004 | Br J Cancel2004，91，8： | 1 |
| 6 | Fibrous Dysplasia as a Stem Cell Disease显示文摘 | Riminucci M Saggio I Robey GP | 2007 | J Bone Miner Res2007，21，： | 1 |
| 7 | Multicenter phase Ⅱ study of CPT-11 fractionated over two days with bi- monthly leucovorin and 5-fluorouracil in patients with metastatic colorectal cancer显示文摘 | Recchia F Nuzzo A Lalli A Di Lullo L De Filippis S Saggio G Di Blasio A Rea S | 2002 | Anticancer Research2002，23，： | 1 |
| 8 | A real time FFT- based impedance meter with bias compensation显示文摘 | ACCATYATIS A SAGGIO G GIANNINI F | 2011 | Measurement2011，44，4： | 1 |
| 9 | Multicenter phase 2 study of interleukin-2 and 13-cis retinoic acid as maintenance therapy in advanced non-small-cell lung cancer显示文摘 | Recchia F Saggio G Nuzzo A | 2006 | Immunother2006，29，1： | 1 |
| 10 | Chemo- immunotherapy in the treatment of metastatic gastric cancer 显示文摘 | Recchia F Saggio G Candeloro G | 2007 | Anticancer Drugs2007，18，5： | 1 |
| 11 | Multicentre phase Ⅱ study of bifractionated CPT-11 with bimonthly leucovorin and 5-fluorouracil in patients with metastatic colorectal cancer pretreated with FOLFOX显示文摘 | RECCHIA F SAGGIO G NUZZO A | 2004 | Br J Cancer2004，91，8： | 1 |
| 12 | Gonadotropin-releasing hormone analogues added to adjuvant chemotherapy protect o- varian function and improve clinical outcomes in young women with early breast carcinoma显示文摘 | Recchia F Saggio G Amiconi G | 2006 | Cancer2006，106，： | 1 |
| 13 | Self-Renewing Osteoprogenitors in Bone Marrow Sinusoids Can Organize a Hematopoietic Microenvironment显示文摘 | Benedetto Sacchetti Alessia Funari Stefano Michienzi Silvia Di Cesare Stefania Piersanti Isabella Saggio Enrico Tagliafico Stefano Ferrari Pamela Gehron Robey Mara Riminucci Paolo Bianco | 2007 | Cell2007，，2： | 1 |
| 14 | 显示文摘 | Jeannine Saggio - Woyansky Curtis E Scott Minnear W P | 1992 | Anierican Ceramics Society Bulletin1992，71，： | 1 |
| 15 | Muhicenter phase Ⅱ study of chemo-immunotherapy in the treatment of metastatic renal cell carcinoma 显示文摘 | Recchia F Saggio G Amiconi G | 2007 | J Immunother2007，30，4： | 1 |
| 16 | Modelling basin scale waves in a stratified lake 显示文摘 | HODGES B R IMBERGER J SAGGIO A | 2000 | Limnology and Oceanography2000，45，7： | 1 |
| 17 | Macrodactyly,syndactyly,and localized gigantism of the forefoot A case report显示文摘 | Saggio ME | 2005 | Chir Organi Mov2005，90，4： | 1 |
| 18 | Modeling basin-scale internal waves in a stratified lake显示文摘 | HODGES B R IMBERGER J SAGGIO A | 2000 | Limnology and Oceanography2000，45，7： | 1 |
| 19 | Phase I study of liposomal Doxorubicin and Oxaliplatin as salvage chemotherapy in advanced ovarian cancer显示文摘 | Recchia F De Filippis S Saggio G | 2003 | Anticanc Drugs2003，14，8： | 1 |
| 20 | CNTF variants with increased biological potency and receptor selectivity define a functional site of receptor interaction显示文摘 | Saggio I Gloaguen I Poiana G | 1995 | EMBO J1995，14，： | 1 |
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