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| 1 | Vascular depression for radiology: A review of the construct,methodology,and diagnosis显示文摘Vascular depression(VD)as defined by magnetic resonance imaging(MRI)has been proposed as a unique subtype of late-life depression.The VD hypothesis posits that cerebrovascular disease,as characterized by the presence of MRIdefined white matter hyperintensities,contributes to and increases the risk for depression in older adults.VD is also accompanied by cognitive impairment and poor antidepressant treatment response.The VD diagnosis relies on MRI findings and yet this clinical entity is largely unfamiliar to neuroradiologists and is rarely,if ever,discussed in radiology journals.The primary purpose of this review is to introduce the MRI-defined VD construct to the neuroradiology community.Case reports are highlighted in order to illustrate the profile of VD in terms of radiological,clinical,and neuropsychological findings.A secondary purpose is to elucidate and elaborate on the measurement of cerebrovascular disease through visual rating scales and semi-and fully-automated volumetric methods.These methods are crucial for determining whether lesion burden or lesion severity is the dominant pathological contributor to VD.Additionally,these rating methods have implications for the growing field of computer assisted diagnosis.Since VD has been found to have a profile that is distinct from other types of late-life depression,neuroradiologists,in conjunction with psychiatrists and psychologists,should consider VD in diagnosis and treatment planning. | Sara N Rushia Al Amira Safa Shehab Jeffrey N Motter Dakota A Egglefield Sophie Schiff Joel R Sneed Ernst Garcon | 2020 | World Journal of Radiology2020，12，5： | 5 |
| 2 | Pressure distribution under a ball impacting a thin lubricant layer 显示文摘 | Safa M M A Gohar R | 1986 | Trans ASME Journal of Tribology1986，108，： | 1 |
| 3 | Inhibition of transforming growth factor beta prevents progression of liver fibrosis and enhances hepatocyte regeneration in dimethylnitrosamine-treated rats显示文摘 | Nakamura T Sakata R Ueno T Safa M Ueno H | | 0，，： | 1 |
| 4 | RNA helicase A in the MEF1 transcription factor complex up-regulates the MDR1 gene in multidrug-resistant cancer cells显示文摘 | ZHONG X SAFA A R | 2004 | J Biol Chem2004，279，17： | 1 |
| 5 | Oscillatory potentials and the b-wave: partial masking and interdependence in dark adaptation and diabetes in the rat显示文摘 | Layton C J Safa R Osborne NN | 2007 | Graefes Arch Clin Exp Ophthalmol2007，245，9： | 1 |
| 6 | Male breast cancer in the veterans affairs population: a comparative analysis 显示文摘 | Nahleh ZA Srikantiah R Safa M | 2007 | Cancer2007，109，8： | 1 |
| 7 | Down-regulation of apoptosis-related bcl-2 but not bcl-xL or bax proteins in multidrug-resistant MCF-7/Adr human breast cancer cells显示文摘 | OGRETMEN B SAFA A R | 1996 | Int J Cancer1996，67，5： | 1 |
| 8 | Malebrea stcancerin the veter- an saffair spopulation :acomparative analysis显示文摘 | Nahleh ZA Srikantiah R Safa M | 2007 | Cancer2007，109，： | 1 |
| 9 | Pressure Distribution Under a Bali Impacting a Thin Lubricant Layer 显示文摘 | Safa M M A Gohar R | 1986 | ASME Journal of Tribology1986，108，： | 1 |
| 10 | Malebrea stcancerin the veteransaffair spopulation : acomparativeanalysis 显示文摘 | Nahleh ZA Srikantiah R Safa M | 2007 | Cancer2007，109，： | 1 |
| 11 | Negative regulation of MDR1 promoter activity in MCF-7,but not in multidrug resistant MCF-7/ADR, cells by Cross-coup led NF-kappa B/p65 and c-Fostranscription factors and their interaction with the CAAT region显示文摘 | OGRETMEN B SAFA A R | 1999 | Biochemistry1999，38，7： | 1 |
| 12 | Vinblastine photoaffinity labeling of a high molecular weight surface membrane glycoprotein specific for multidrug-resistant cells 显示文摘 | Safa A R Glover C J Meyers M B | 1986 | J Biol Chem1986，261，14： | 1 |
| 13 | Male breast canc- er in the veterans affairs population: a comparative analysis 显示文摘 | Nahleh ZA Srikantiahm R Safa M | 2007 | Cancer2007，109，8： | 1 |
| 14 | c-FLIP(L) ,a master anti-apoptotic regulator显示文摘 | SAFA A R | 2012 | Exp Onco12012，34，3： | 1 |
| 15 | Cellular FLICE- like inhibitory protein( C-FLIP(L) ) :a novel target for cancer therapy显示文摘 | AHMAD R SAFA A R TRAVIS W D | 2008 | Current Cancer Drug Targets2008，8，： | 1 |
| 16 | Down-regulation of apoptosis-related bcl-2 but not bcl-xL or bax proteins in muhidrug-resistant MCF-7/Adr human breast cancer cells 显示文摘 | Ogretmen B Safa A R | 1996 | Int J Cancer1996，67，5： | 1 |
| 17 | c-FLIP,A MASTER ANTI-APOPTOTIC REGULATOR显示文摘 | Safa A R | 2012 | Experimental oncology2012，34，3： | 1 |
| 18 | Melatonin protects primary cultures of rat cortical neurones from NMDA excitotoxicity and hypoxia/reoxygenation显示文摘 | CAZEVIEILLE C SAFA R OSBOME N N | 1997 | Brain Res1997，768，12： | 1 |
| 19 | Increased expression of lung resistance related protein and multidrug resistance associated protein mRNA in childhood acute lymphoblastic leukemia显示文摘 | OGRETMEN B BARREDO J C SAFA A R | 2000 | Leukemia2000，22，1： | 1 |
| 20 | Cellular FLICE-like inhibitory protein (C-FLIP) : a novel target for cancer therapy 显示文摘 | Safa A R Day T W Wu C H | 2008 | CUff Cancer Drug Targets2008，8，1： | 1 |
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