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| 1 | Evolution of transanal total mesorectal excision for rectal cancer:From top to bottom显示文摘The gold standard for curative treatment of locally advanced rectal cancer involves radical resection with a total mesorectal excision(TME). TME is the most effective treatment strategy to reduce local recurrence and improve survival outcomes regardless of the surgical platform used. However, there are associated morbidities, functional consequences, and quality of life(QoL) issues associated with TME; these risks must be considered during the modern-day multidisciplinary treatment for rectal cancer. This has led to the development of new surgical techniques to improve patient, oncologic, and QoL outcomes. In this work, we review the evolution of TME to the transanal total mesorectal excision(TaTME) through more traditional minimally invasive platforms. The review the development, safety and feasibility, proposed benefits and risks of the procedure, implementation and education models, and future direction for research and implementation of the TaTME in colorectal surgery. While satisfactory short-term results have been reported, the procedure is in its infancy, and long term outcomes and definitive results from controlled trials are pending.As evidence for safety and feasibility accumulates,structured training programs to standardize teaching,training, and safe expansion will aid the safe spread of the TaTME. | Sameh Hany Emile F Borja de Lacy Deborah Susan Keller Beatriz Martin-Perez Sadir Alrawi Antonio M Lacy Manish Chand | 2018 | World Journal of Gastrointestinal Surgery2018，10，3： | 18 |
| 2 | Heparan sulfate/heparin oligosaccharides protect stromal cell-derived factor-1(SDF-1)/CXCL12 against proteolysis induced by CD26/dipeptidyl peptidase IV显示文摘 | Sadir R Imberty A Baleux F Lortat-Jacob H | 2004 | J Biol Chem2004，279，43： | 1 |
| 3 | The effect of delive- ring the chemokine SDF-1 alpha in a matrix-bound man- ner on myogenesis 显示文摘 | Dalonneau F Liu XQ Sadir R | 2014 | Biomaterials2014，35，15： | 1 |
| 4 | The efficacy of ozonc therapy in experimental caustic esophageal burn显示文摘 | Guven A Gundogdu G Sadir A | 2008 | J Pediatr Surg2008，43，9： | 1 |
| 5 | Oxidative stress levels in rats following exposure to oxygen at 3 arm for 0-120 min显示文摘 | OterS Topal T Sadir S | 2007 | Aviat Space Eniron Med2007，78，12： | 1 |
| 6 | Exposure time related oxidative action of hyperbaric oxygen in rat brain显示文摘 | Korkmaz A Oter S Sadir S | 2008 | Neurochem Res2008，33，： | 1 |
| 7 | Exposure time related oxidative action of hyperbaric oxygen in rat brain显示文摘 | Korkmaz A Oter S Sadir S | 2008 | Neurochem Res2008，33，1： | 1 |
| 8 | Down-regulation by progesterone of CFTR expression in endometrial epithelial cells:a study by competitive RT-PCR显示文摘 | MULARONI A BECK L SADIR R | 1995 | Biochem Biophy Res Commun1995，217，3： | 1 |
| 9 | Induction of a Protective Antibody Response to Foot and Mouth Disease Virus in Mice Following Oral or Parenteral Immunization with Alfalfa Transgenic Plants Expressing the Viral Structural Protein VP1显示文摘 | Andrés Wigdorovitz Consuelo Carrillo Mar??a J. Dus Santos Karina Trono Andrea Peralta Mar??a C. Gómez Raúl D. R??os Pascual M. Franzone Ana M. Sadir José M. Escribano Manuel V. Borca | 1999 | Virology1999，，2： | 1 |
| 10 | Exposure time related oxidative action of hyperbaric oxygen in rat brain 显示文摘 | Korkmaz A Oter S Sadir S | 2008 | Neurochem Res2008，33，1： | 1 |
| 11 | Detection of foot and mouth disease virus with DNA probes in bovine esophagealpharyngeal fluids 显示文摘 | Rossi M S Sadir A M Schudel A A | 1988 | Archives of Virology1988，99，12： | 1 |
| 12 | Repeated administration of al- monds increases brain acetylcholine levels and enhances memory function in healthy rats while attenuates memory deficits in animal model of amnesia显示文摘 | Batool Z Sadir S Liaquat L | 2015 | Brain Res Bull2015，120，： | 1 |
| 13 | Aberrant Crypt Foci 显示文摘 | Sadir J Alrawi M Robert E | 2006 | Anti- cancer Res2006，26，1： | 1 |
| 14 | Induction of a protective antibody response to foot and mouth disease virus in mice following oral or parenteral immunization with alfalfa transgenic plants expressing the viralstrural protin VP1显示文摘 | WIGDOROVITZ A CARRILLO C DUS SANTOS M J TRONO K PERALTA A GMEZ M C ROS R D FRANZONE P M SADIR A M ESCRIBANO J M BORCA M V | 1999 | Virology1999，255，2： | 1 |
| 15 | Protection of mice against challenge with foot and mouth disease virus (FMDV) by immunization with foliar extracts form plants infected with recombinant tobacco mosaic virus expressing the FMDV structural protin VP1显示文摘 | WIGDOROVITZ A PEREZ FILGUEIRA D M ROBERTSON N CARRILLO C SADIR A M MORRIS T J BORCA M V | 1999 | Virology1999，264，1： | 1 |
| 16 | Characterization of the stromal cell-derived factor-1a-heparin complex 显示文摘 | Sadir R Baleux F Grosdidier A | 2001 | J Biol Chem2001，276，11： | 1 |
| 17 | Oxidative stress levels in rats following exposure to oxygen at 3 for 0-120min 显示文摘 | Oter S Topal T Sadir S | 2007 | Aviat Space Environ Med2007，78，12： | 1 |
| 18 | Down-regulation by progesterone of CFTR expression in endometrial epithelial cells: a study by competitive RT-PCR显示文摘 | Mularoni A Beck L Sadir R | 1995 | Biochem Biophys Res Commun1995，217，3： | 1 |
| 19 | Foot-and-mouth disease virus (FMDV) experimental infection: Susceptibility and immune response of adult mice 显示文摘 | Fernandez F M Borca M V Sadir A M | 1986 | Veter Microbiol1986，12，： | 1 |
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