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| 1 | Air quality monitoring using mobile microscopy and machine learning显示文摘Rapid,accurate and high-throughput sizing and quantification of particulate matter(PM)in air is crucial for monitoring and improving air quality.In fact,particles in air with a diameter of≤2.5μm have been classified as carcinogenic by the World Health Organization.Here we present a field-portable cost-effective platform for high-throughput quantification of particulate matter using computational lens-free microscopy and machine-learning.This platform,termed c-Air,is also integrated with a smartphone application for device control and display of results.This mobile device rapidly screens 6.5 L of air in 30 s and generates microscopic images of the aerosols in air.It provides statistics of the particle size and density distribution with a sizing accuracy of~93%.We tested this mobile platform by measuring the air quality at different indoor and outdoor environments and measurement times,and compared our results to those of an Environmental Protection Agency–approved device based on beta-attenuation monitoring,which showed strong correlation to c-Air measurements.Furthermore,we used c-Air to map the air quality around Los Angeles International Airport(LAX)over 24 h to confirm that the impact of LAX on increased PM concentration was present even at 47 km away from the airport,especially along the direction of landing flights.With its machinelearning-based computational microscopy interface,c-Air can be adaptively tailored to detect specific particles in air,for example,various types of pollen and mold and provide a cost-effective mobile solution for highly accurate and distributed sensing of air quality. | Yi-Chen Wu Ashutosh Shiledar Yi-Cheng Li Jeffrey Wong Steve Feng Xuan Chen Christine Chen Kevin Jin Saba Janamian Zhe Yang Zachary Scott Ballard Zoltán Göröcs Alborz Feizi Aydogan Ozcan | 2017 | Light(Science & Applications)2017，6，1： | 5 |
| 2 | Cigarette smoking, dietary habits and genetic polymorphisms in GSTT1, GSTM1 and CYP1A1 metabolic genes: A case-control study in oncohematological diseases显示文摘AIM To analyze the association between oncohematological diseases and GSTT1 /GSTM1 /CYP1A1 polymorphisms, dietary habits and smoking, in an argentine hospitalbased case-control study.METHODS This hospital-based case-control study involved 125 patients with oncohematological diseases and 310 control subjects. A questionnaire was used to obtain sociodemographic data and information about habits. Blood samples were collected, and DNA was extracted using salting out methods. Deletions in GSTT1 and GSTM1 (null genotypes) were addressed by PCR. CYP1A1 MspI polymorphism was detected by PCR-RFLP. Odds ratio(OR) and 95%CI were calculated to estimate the association between each variable studied and oncohematological disease.RESULTS Women showed lower risk of disease compared to men(OR 0.52, 95%CI: 0.34-0.82, P = 0.003). Higher levels of education(> 12 years) were significantly associated with an increased risk, compared to complete primary school or less(OR 3.68, 95%CI: 1.82-7.40, P < 0.001 adjusted for age and sex). With respect to tobacco, none of the smoking categories showed association with oncohematological diseases. Regarding dietary habits, consumption of grilled/barbecued meat 3 or more times per month showed significant association with an increased risk of disease(OR 1.72, 95%CI: 1.08-2.75, P = 0.02). Daily consumption of coffee also was associated with an increased risk(OR 1.77, 95%CI: 1.03-3.03, P = 0.03). Results for GSTT1, GSTM1 and CYP1A1 polymorphisms showed no significant association with oncohematological diseases. When analyzing the interaction between polymorphisms and tobacco smoking or dietary habits, no statistically significant associations that modify disease risk were found. CONCLUSION We reported an increased risk of oncohematological diseases associated with meat and coffee intake. We did not find significant associations between genetic polymorphisms and blood cancer. | María Belén Cerliani Walter Pavicic Juan Antonio Gili Graciela Klein Silvia Saba Silvina Richard | 2016 | World Journal of Clinical Oncology2016，7，5： | 1 |
| 3 | Developing a green building assessment tool for developing countries-Case of Jordan 显示文摘 | Hikmat HA Saba F A N | 2008 | Building and Environment2008，44，5： | 1 |
| 4 | Seven strategies for enabling faculty success in distance education显示文摘 | HOWELL S L SABA F LINDSAY N K WILLIAMS P B | 2004 | Internet and higher education2004，，7： | 1 |
| 5 | Beyond Borders : Building Global HealthPrograms at McGill University Faculty of Medicine 显示文摘 | Saba N Brewer TF | 2008 | AcademicMedicine2008，83，2： | 1 |
| 6 | From boutique to basic: a call for standardised medical education in global health 显示文摘 | Brewer T F Saba N Glair V | 2009 | Medical Education2009，43，： | 1 |
| 7 | Requirement for pectin methyl esterase and preference for fragmented over native pectins for wall-associated kinase-activted, EDS1/PAD4 - dependent stress response in Arabidopsis 显示文摘 | Kohorn B D Kohorn S L Saba N J Martinez V M | 2014 | Journal of Biological Chemistry2014，289，18： | 1 |
| 8 | Blood coagulation in patients with chronic heart failure: evidence for hypereoagulable state and potential for pharmacological intervention 显示文摘 | De Lorenzo F Saba N Kakkar VV | 2003 | Drugs2003，63，6： | 1 |
| 9 | Beyond borders:building global health pro-grams at McGill University Faculty of Medicine 显示文摘 | Saba N Brewer TF | 2008 | Acad Med2008，83，2： | 1 |
| 10 | Requirement for pectin methyl esterase and preference for fragmented over native pectins for wall associated kinase activated, EDS1/PAD4-dependent stress response in Arabidopsis显示文摘 | Kohorn B D Kohorn S L Saba N J | 2014 | Journal of Biological Chemistry2014，289，18： | 1 |
| 11 | Risk factors for rising incidence of esophageal and gastric cardia adenocarcinoma 显示文摘 | Carr JS Zafar SF Saba N | 2013 | J Gastroint- est Cancer2013，44，2： | 1 |
| 12 | High treatment-related mortalityin cardiac amyloid patients undergoing autologus stem cell trans-plant显示文摘 | Saba N Sutton D Ross H | 1999 | Bone Marrow Transplant1999，24，： | 1 |
| 13 | Blood coagulation in patients withchronic heart failure:evidence for hypercoagulable state and potentialfor pharmacological intervention显示文摘 | De Lorenzo F Saba N Kakkar V V | 2003 | Drugs2003，63，6： | 1 |
| 14 | Mammalian BarH1 confers commissural neuron identity on dorsal cells in the spinal cord显示文摘 | Saba R Nakatsuji N Saito T | 2003 | J Neurosci2003，23，6： | 1 |
| 15 | Bone marrow transplantation for nonmalignant diseases显示文摘 | Saba N Flaiq T | 2002 | J Hematother Stem Cell Res2002，11，2： | 1 |
| 16 | Lightning current observation of an altitude-triggered flash显示文摘 | Saba M M F O P Jr N N Solorzano | 2005 | Atmos Res2005，76，： | 1 |
| 17 | From boutique to basic:a callfor standardised medical education in global health 显示文摘 | Brewer TF Saba N Clair V | 2009 | MedEduc2009，43，10： | 1 |
| 18 | Blood coagulation in patients with chronic heart failure: evidence for hypercoagulable state and potential for pharmacological intervention显示文摘 | De Lorenzo F Saba N Kakkar VV | 2003 | Drugs2003，63，6： | 1 |
| 19 | Examining expression of folate receptor in squamous cell carcinoma of the head and neck as a target for a novel nanotherapeutic drug 显示文摘 | Saba N F Wang X Mtiller S | 2009 | Head Neck2009，31，47： | 1 |
| 20 | Lightning current observation of an altitude-triggered flash显示文摘 | Saba M M F Pinto O Solorzano N N | 2005 | Atmospheric Research2005，76，14： | 1 |
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