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    题名 作者 年代 出处 被引量
1Pineal clock gene oscillation is disturbed in Alzheimer's disease, due to functional disconnection from the "master clock"显示文摘Wu YH Fischer DF Kalsbcck A Garidou-Boof ML van der Vliet J van Heijningen C Liu RY Zhou JN Swaab DE 2006中国生物学文摘2006,20,9:7
2Quanti?cation of Tyrosine Hydroxylase and Erb B4 in the Locus Coeruleus of Mood Disorder Patients Using a Multispectral Method to Prevent Interference with Immunocytochemical Signals by Neuromelanin显示文摘The locus coeruleus(LC) has been studied in major depressive disorder(MDD) and bipolar disorder(BD). A major problem of immunocytochemical studies in the human LC is interference with the staining of the immunocytochemical end-product by the omnipresent natural brown pigment neuromelanin. Here, we used a multispectral method to untangle the two colors: blue immunocytochemical staining and brown neuromelanin.We found significantly increased tyrosine hydroxylase(TH) in the LC of MDD patients—thus validating the method—but not in BD patients, and we did not find significant changes in the receptor tyrosine-protein kinase ErbB4 in the LC in MDD or BD patients. We observed clear co-localization of ErbB4, TH, and neuromelanin in the LC neurons. The different stress-related molecular changes in the LC may contribute to the different clinical symptoms in MDD and BD.Lei Guo Jochem StormmesAND Zheng Fang Qingbin Zhu Rawien Balesar Joop van Heerikhuize Arja Sluiter Dick Swaab Ai-Min Bao 2019Neuroscience Bulletin2019,35,2:2
3Progress in Human Brain Banking in China显示文摘Human brain banks collect,preserve,and distribute postmortem and biopsied brain samples for histological,pathological,and molecular research.Different from the western countries,human brain banking in China has remained preliminary over decades.However,joint efforts during the past few years have substantially promoted this key frontier of neuroscience in China.This special topic brings together review and perspective articles on the ethical,administrative,and practical issues of brain banking.Several original studies report molecular and pathological characterizations based on banked human brain samples.Chao Ma Ai-Min Bao Xiao-Xin Yan Dick F. Swaab 2019Neuroscience Bulletin2019,35,2:2
4Psychiatric characteristics in a self-selected sample of boys with Klinefeher syndrome 显示文摘Bruining H Swaab H Kas M 2009Pediatrics2009,123,5:1
5Activation of vasopressin neurons in the human supraoptic and paraventricular nucleus in senescence and senile dementia显示文摘Hoogendijk JE Fliers E Swaab DF 1985J Neurol Sci1985,69,:1
6Changes in estrogen receptor-alpha andbeta in the infundibular nucleus of the human hypothalamus are related to the occurrence of Alzheimer s disease neuropathology显示文摘Hestiantoro A Swaab D F 2004Journal of Clinical Endocrinology&Metabolism2004,89,4:1
7Reduced neuronal activity and reactivation in Alzheimer's disease 显示文摘 Lucassen PJ Salehi A 1998Prog Brain Res1998,117,:1
8查看详情显示文摘van Rijn S Aleman A Swaab H 0,,06:1
9The vasopressin and oxytocin neurons in the human supraoptic and paraventricular nucleus changes with aging and in senile dementi显示文摘Fliers E Swaab DF Pool CW 1985Brain Res1985,342,:1
10The sexually dimorphic nucleus of the preoptic area in the human brain: a comparative morphometrie study 显示文摘Hofman MA Swaab DF 1989J Anat1989,164,:1
11Alterations in the hypothalamic paraventricular nucleus and its oxytocin neurons(putative satiety cells)in Prader-Willi syndrome:a study of five cases显示文摘SWAAB D F PURBA J S HLFMAN M A 1995Journal of Clinical Endocrinology & Metabolism1995,80,:1
12Reactivation of atrophic neurons in Alzheimers disease显示文摘Swaab DF 2003Neurol Res2003,25,6:1
13查看详情显示文摘Bruining H Swaab H Kas M 0,,05:1
14Disturbance and strategies forreactivation of the circadian rhythm system in aging andAlzheimer's disease显示文摘Wu YH Swaab DF 2007Sleep Med2007,8,6:1
15The human pineal gland and melatonin inaging and Alzheimer's disease显示文摘Wu YH Swaab DF 2005J Pineal Res2005,38,3:1
16Pain processing in dementia and its relation to neuropathology 显示文摘Scherder E J Sergeant JA Swaab DF 2003Lancet Neurol2003,2,:1
17Estrogen receptor-alpha splice variants in the human brain 显示文摘Ishunina TA Swaab DF 2008Gynecol Endocfinol2008,24,2:1
18The stress system in depres- sion and neurodegeneration:focus on the human hypothala- mus显示文摘Bao AM Meynen G Swaab DF 2008Brain Res Rev2008,57,2:1
19Social influence in small groups- An interactive model of social identity formation 显示文摘Postmes T Haslam S A Swaab R 2005European Review of Social Psychology2005,16,1:1
20Effects of transcutaneous electrical nerve stimulation (TENS) on memory in elderly with mild cognitive impairment显示文摘 Swaab DF Sergeant JA 2005Behav Brain Res2005,,2:1
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