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| 1 | Ultrasound-assessed non-culprit and culprit coronary vessels differ by age and gender显示文摘AIM: To investigate age-and gender-related differences in non-culprit versus culprit coronary vessels assessed with virtual histology intravascular ultrasound (VH-IVUS). METHODS: In 390 patients referred for coronary angiography to a single center (Luzerner Kantonsspital, Switzerland) between May 2007 and January 2011, 691 proximal vessel segments in left anterior descending, circumflex and/or right coronary arteries were imaged by VH-IVUS. Plaque burden and plaque composition(fibrous, fibro-fatty, necrotic core and dense calcium volumes) were analyzed in 3 age tertiles, according to gender and separated for vessels containing non-culprit or culprit lesions. To classify as vessel containing a culprit lesion, the patient had to present with an acute coronary syndrome, and the VH-IVUS had to be performed in a vessel segment containing the culprit lesion according to conventional coronary angiography. RESULTS: In non-culprit vessels the plaque burden increased significantly with aging (in men from 37% ± 12% in the lowest to 46% ± 10% in the highest age tertile, P < 0.001; in women from 30% ± 9% to 40% ± 11%, P < 0.001); men had higher plaque burden than women at any age (P < 0.001 for each of the 3 age tertiles). In culprit vessels of the lowest age tertile, plaque burden was significantly higher than that in non- culprit vessels (in men 48% ± 6%, P < 0.001 as compared to non-culprit vessels; in women 44% ± 18%, P = 0.004 as compared to non-culprit vessels). Plaque burden of culprit vessels did not significantly change during aging (plaque burden in men of the highest age tertile 51% ± 9%, P = 0.523 as compared to lowest age tertile; in women of the highest age tertile 49% ± 8%, P = 0.449 as compared to lowest age tertile). In men, plaque morphology of culprit vessels became increasingly rupture-prone during aging (increasing percentages of necrotic core and dense calcium), whereas plaque morphology in non-culprit vessels was less rupture-prone and remained constant during aging. In women, necrotic core in non-culprit vessels was very low at young age, but increased during aging resulting in a plaque morphology that was very similar to men. Plaque morphology in culprit vessels of young women and men was similar. CONCLUSION: This study provides evidence that age-and gender-related differences in plaque burden and plaque composition significantly depend on whether the vessel contained a non-culprit or culprit lesion. | Andreas W Schoenenberger Nadja Urbanek Stefan Toggweiler Andreas E Stuck Thérèse J Resink Paul Erne | 2013 | World Journal of Cardiology2013，5，3： | 7 |
| 2 | Ego depletion and aggressive behavior: Is the inhibition of aggression a limited resource? 显示文摘 | Stucke T S Baumeister R F | 2006 | European Journal of Social Psychology2006，，： | 1 |
| 3 | Advanced intermetallic alloys-beyond gamma titanium aluminides显示文摘 | SUBRAMANIAN P R MENDIRATTA M G DIMIDUK D M STUCKE M A | 1997 | Mater Sci Eng A1997，，： | 1 |
| 4 | Mortality risk of Charcot arthropathy compared with that of diabetic foot ulcer and diabetes alone显示文摘 | Sohn M W Lee T A Stuck R M | 2009 | Diabetes Care2009，32，5： | 1 |
| 5 | Raising the priority of preventing chronic diseases: a political process显示文摘 | Geneau R Stuck|er D Stachenko S | 2010 | Lancet2010，，369： | 1 |
| 6 | Influence of cultivars and pesticides on pea aphid, spotted alfalfa aphid, and associated arthropod taxa in a Minnesota alfalfa ecosystem显示文摘 | Radcliffe E B Weires R W Stuck er R E | 1976 | Environmental Entomology1976，5，6： | 1 |
| 7 | Strong improvement of diffusion length by phosphorus and aluminum gettering显示文摘 | Loghmarti M Stuck R Muller J C | 1993 | Applied Physics Letters1993，62，9： | 1 |
| 8 | Diag- nostic accuracy of existing methods for identifying diabetic foot ulcers from inpatient and outpatient datasets 显示文摘 | Sohn M W Budiman-Mak E Stuck R M | 2010 | J Foot Ankle Res2010，3，： | 1 |
| 9 | Mortality risk of Char- cot arthropathy compared with that of diabetic foot ulcer and di- abetes alone 显示文摘 | Sohn M W Lee T A Stuck R M et aI | 2009 | Diabetes Care2009，32，5： | 1 |
| 10 | Properties of Vapour Phase Grown Mercuric Iodide Single Crystal Detectors显示文摘 | Ponpon J P Stuck R Siffert P | 1975 | IEEE Transaction Nuclear Science1975，22，1： | 1 |
| 11 | Stabilization of RuO2 by IrO2 for anodic oxygen evolution in acid media 显示文摘 | KOTZ R STUCK/ S | 1986 | Electrochim Acta1986，31，： | 1 |
| 12 | Intraoperative cone beam compu- ted tomography in the management of facial fractures 显示文摘 | Stuck BA Hulse R Barth TJ | 2012 | Int J Oral Maxillofac Surg2012，41，10： | 1 |
| 13 | Strong improvement of diffusion length by phosphorus and aluminum gettering显示文摘 | Loghmarti M Stuck R Muller J C | 1993 | Applied Physics Letters1993，62，： | 1 |
| 14 | Results of a Prospective Randomised Open Label Phase Ill Study Comparing Rituximab Plus Mitoxantrone, Chlorambucile, Prednisolone Chemotherapy (R-MCP) Versus MCP Alone in Untreated Advanced Indolent Non-Hodgkin' s Lymphoma (NHL) and Mantle-Cel-Lymphoma (MCL) 显示文摘 | Herold M Pasold R Stuck S | 2004 | Blood2004，104，： | 1 |
| 15 | Nonlinear stability problem of an open conical sandwich shell under external pressure and compression 显示文摘 | Stuck R | 1984 | International Journal of Non-Linear Mechanics1984，19，3： | 1 |
| 16 | Strong improve-ment of diffusion length by phosphorus and aluminum gette- ring显示文摘 | Loghmarti M Stuck R Muller J C | 1993 | Appl Phys Lett1993，62，9： | 1 |
| 17 | Advanced intermetallic alloys-Beyond gamma titanium aluminides 显示文摘 | Subramanian P R Mendiratta M G Dimiduk D M Stucke M A | 1997 | MateriaLs Science and Engineering A1997，，： | 1 |
| 18 | Advanced intermetallic alloys-beyond gamma titanium aluminides 显示文摘 | Subramanian P R Mendiratta M G Dimiduk D M Stucke M A | 1997 | Materials Science and Engineering A1997，，2： | 1 |
| 19 | Advanced intermetallic alloys-beyond gamma titanium aluminides 显示文摘 | Subramanian P R Mendiratta M G Dimiduk D M Stucke M A | 1997 | Materials Science and Engineering: A1997，239，： | 1 |
| 20 | Strong improvement of diffusion length by phosphorus and aluminum gettering显示文摘 | LOGHMARTI M STUCK R MULLER J C | 1993 | Appl Phys Lett1993，62，： | 1 |
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