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| 1 | Hemobilia as the initial manifestation of cholangiocarcinoma in a hemophilia B patient显示文摘Hemobilia is a rare manifestation of hemophilia and is usually iatrogenic following liver biopsy. There are only few reports of spontaneous hemobilia in hemophilia patients. Cholangiocarcinoma is a well-established cause of hemobilia. We describe a case of a 70-year-old male, with known haemophilia B and a past history of papillotomy, who presented with classical symptoms of hemobilia. The initial diagnostic work-up failed to demonstrate a potential cause of bleeding other than the coagulopathy. Three months later, he was readmitted to our hospital with a second episode of hemobilia. During the second work-up, a cholangiocarcinoma was diagnosed both by imaging studies and by a significant elevation of cancer antigen 19-9. Although hemobilia could be attributed to hemophilia, especially in a patient with previous papillotomy, an underlying malignancy of the biliary tree should be suspected. | Anastassios C Manolakis Andreas N Kapsoritakis Antonis D Tsikouras Fotis D Tsiopoulos Athanassios K Psychos Spyros P Potamianos | 2008 | World Journal of Gastroenterology2008，14，26： | 5 |
| 2 | Application of different analytical methods for determination of volatile chlorination by-products in drinking water 显示文摘 | Anastasia D Nikolaou Themistokles D Lekkas Spyros K Golfinopoulos | 2002 | Talanta2002，56，4： | 1 |
| 3 | Comparison of methods for determination of volatile organic coinpounds in drinking water显示文摘 | Spyros K Golllnopoulos Themistokles D Lekkas Anastasia D Nikolaou | 2001 | Chemosphere2001，45，3： | 1 |
| 4 | Chlorination by-products and canca:Meta-Analgsis显示文摘 | Morrio R D Spyros K G George B A | 1992 | Am J Public Health1992，80，： | 1 |
| 5 | Determination of haloacetic acids in water by acidic methanol esterification - GC - ECD method显示文摘 | ANASTASIA D N SPYROS K G MARIA N | 2002 | Water Res2002，36，： | 1 |
| 6 | Notch Signaling:Cell Fate Control and Signal Integration in Development显示文摘 | Spyros Artavanis-Tsakonas Matthew D Rand Robert J Lake | 1999 | Scinence1999，4，30： | 1 |
| 7 | Notch signaling:cell fate control and signal integration in development显示文摘 | Spyros A T Matthew D R Robert | 1999 | Science1999，284，： | 1 |
| 8 | Organochlorine pesticides in the surface waters of Northern Greece 显示文摘 | Spyros K G Anastasia D N Maria N K | 2003 | Chemosphere2003，50，4： | 1 |
| 9 | Dynam-ic light scattering vs 1H NMR investigation of pH-re-sponsive diblock copolymers in water显示文摘 | Vamvakaki M Palioura D Spyros A | | Macromole-cules0，39，： | 1 |
| 10 | Double-loop suture repair for acute acromioclavicular joint disruption显示文摘 | Panayotis D Andreas P Spyros AS | 2006 | The American Journal of Sports Medicine2006，34，7： | 1 |
| 11 | Deterministic and stochastic analyses of a nonlinear system with a Biot visco-elastic element显示文摘 | Pol D Spanos Spyro Tsavachidis | 2001 | J Earthquake Engng Struct Dyn2001，30，： | 1 |
| 12 | Behavioral and neuro chemical effects induced by chronic mild stress applied to two different rat strains 显示文摘 | Stathis B Katerina A Spyros D | 2005 | Behav Brain Res2005，161，1： | 1 |
| 13 | Determination of haloacetic acids in water byacidic methanol esterification- GC-ECD method 显示文摘 | Anastasia D N Spyros K G Maria N K | 2002 | Water Research2002，36，： | 1 |
| 14 | Organochlorine Pesticides in Surface Waters of Northern Greece 显示文摘 | SPYROS K G ANASTASIA D N MARIA N K | 2003 | Chemo-sphere2003，50，4： | 1 |
| 15 | Organo-chlorine Pesticides in the Surface Waters of Northern Greece显示文摘 | Spyros K G Anastasia D N Maria N K | 2003 | Chemosphere2003，50，4： | 1 |
| 16 | Organochlorine Pesticides in the Surface Water of Northern Greece显示文摘 | Spyros K G Anastasia D N Maria N K | 2003 | Chemosphere2003，50，4： | 1 |
| 17 | Behavioural and neurochemical effects induced by chronic mild stress applied to two different rat strains 显示文摘 | STATHIS B KATERINA A SPYROS D | 2005 | Behavioural Brain Research2005，161，1： | 1 |
| 18 | Early ileocolonoscopy with biopsy for the evaluation of persistent post-transplantation diarrhea显示文摘AIM: To investigate the signifi cance of ileocolonoscopy with histology in the evaluation of post-transplantation persistent diarrhea (PD). METHODS: We retrospectively reviewed all records of renal transplant patients with PD, over a 3-year period. All patients were referred for ileocolonoscopy with biopsy, following a negative initial diagnostic work up. Clinical and epidemiological data were compared between cases with infectious or drug-induced diarrhea. RESULTS: We identif ied 30 episodes of PD in 23 renaltransplant patients (1-3 cases per patient). There were 16 male patients and the mean age at the time of PD was 51.4 years. The average time from transplantation to a PD episode was 62.3 ± 53.2 mo (range 1-199 mo). Ileocolonoscopy detected mucosal abnormalities in 19 cases, whereas the intestinal mucosa appeared normal in 11 cases. Histological examination achieved a specific diagnosis in 19/30 cases (63.3%). In nine out of 11 cases (82%) with normal endoscopic appearance of the mucosa, histological examination of blinded biopsies provided a specif ic diagnosis. The etiology of PD was infectious in 11 cases (36.6%), drug-related in 10 (33.3%), of other causes in three (10%), and of unknown origin in six cases (20%). Infectious diarrhea occurred in significantly longer intervals from transplantation compared to drug-related PD (85.5 ± 47.6 mo vs 40.5 ± 44.8 mo, P < 0.05). Accordingly, PD due to drug-toxicity was rarely seen after the f irst year post-transplantation. Clinical improvement followed therapeutic intervention in 90% of cases. Modif ication of immunosuppressive regimen was avoided in 57% of patients. CONCLUSION: Early ileocolonoscopy with biopsies from both affected and normal mucosa is an important adjunctive tool for the etiological diagnosis of PD in renal transplant patients. | Giorgos Bamias John Boletis Theodoros Argyropoulos Chrysanthi Skalioti Spyros I Siakavellas Ioanna Delladetsima Irene Zouboulis-Vafiadis George L Daikos Spiros D Ladas | 2010 | World Journal of Gastroenterology2010，16，30： | 1 |
| 19 | Toxicity and biodegradability screening of nonionic surfactants using sediment derived methanogenic consortia 显示文摘 | Daniel H Yeh Kurt D Pennell Spyros G Paviostathis | 1998 | Water Science and Technology1998，38，7： | 1 |
| 20 | Biogas production from anaerobic co-digestion of agroindustrial wastewaters under mesophilic conditions in a two-stage process显示文摘 | Margarita A D Spyros N D Katerina S | 2009 | Desalination2009，248，13： | 1 |
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