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	题名	作者	年代	出处	被引量
1	Association of homocysteine and smoking with cerebral microemboli in patients with mechanical heart valves:a transcranial Doppler study显示文摘Objectives Microembolic signals(MES)on transcranial Doppler(TCD)predict stroke and cognitive decline.Plasma levels of total homocysteine(tHcy),a prothrombotic factor,are higher in patients with microemboli in carotid stenosis and in patients with paradoxical embolism.In this study we assessed the association between the level of tHcy and the number of MES in patients with mechanical heart valves(MHVs).Methods TCD monitoring was performed to detect MES before and after breathing 100% oxygen and repeated every 2-4 weeks up to six times.results Twenty-five patients with MHVs(mean age:63.60±10.15 years)participated in this study;15 were men(66.47±7.25 years)and 10 were women(59.30±12.60 years).In total,there were 126 study visits.In multiple regression,higher tHcy was associated with more MES in both preoxygenation(OR 1.34(95%CI 1.07 to 1.68,P=0.009))and postoxygenation(OR 1.40(95% CI 1.07 to 1.83,P=0.01))phases.Current smoking and the length of time between the operation and monitoring also correlated with a higher number of MES before and after breathing oxygen,particularly in women.conclusions Higher tHcy and smoking were associated with a higher MES count in both preoxygenation and postoxygenation phases.Because smoking can be stopped and hyperhomocysteinaemia is treatable,these are clinically important findings.	Alicia Mattia M Reza Azarpazhooh Claudio Munoz Chrysi Bogiatzi Mackenzie A Quantz J David Spence	2017	Stroke & Vascular Neurology2017，2，4：	2
2	The Forgotten Stakeholder? Ethics and Social Respon- sibility in Relation to Competitors 显示文摘	Spence L J Coles A Harris L	2001	Business and Society Review2001，106，4：	1
3	Bi-metal CRA- lined pipe employed for north sea field development显示文摘	Spence M A Roscoe C V	1999	Oil& Gas Journal1999，97，18：	1
4	Job market signaling 显示文摘	Spence A M	1973	Quarterly Journal of Economics1973，87，3：	1
5	Measurement of carotid plaque volume by 3-dimensional ultrasound显示文摘	Landry A Spence JD Fenster A	2004	Stroke2004，35，4：	1
6	Intracranial stenosis predicts higher risk of vascular events in Caucasians with asymptomatic carotid stenosis显示文摘	Tamayo A Spence JD	2005	Stroke2005，36，：	1
7	A mi- crofabricated device for sizing and sorting DNA mol- ecules 显示文摘	Chou Hou-pu Spence C Scherer A	1999	Proceedings of the National Academy of Sciences of the United States of America1999，96，1：	1
8	A microfabricated fluorescence-activated cell sorter 显示文摘	FU A Y SPENCE C SCHERER A	1999	Nature Biotechnology1999，17，11：	1
9	Acupuncture increases nocturnal melatonin secretion reduces insomnia and anxiety:a preliminary report显示文摘	Spence DW Kayumov L Chen A	2004	Neuropsychiatry Clin Neurosci2004，16，1：	1
10	Job Market Signaling显示文摘	Spence A	1973	Quarterly Journal of Economics1973，87，3：	1
11	Job Market Signaling 显示文摘	Spence A M	1973	The Quarterly Journal of Economics1973，，1：	1
12	Resistance of species of theDrosophilamelanogaster subgroupto environmental extremes显示文摘	StanleyS M Parsons P A Spence G E	1980	Australian Journalo{ Zoology1980，28，：	1
13	Characterizing the thermal regime of cold vents at the northern Cascadiamargin from bottom-simulating reflector distributions, heat-probe measurements and borehole temperature data显示文摘	Riedel M Tréhu A Spence G		0，，1：	1
14	IL-27 promotes IL-10 production by effector Thl CD4 ~ T cells : a critical mechanism for protection from severe immunopathology during malaria infection 显示文摘	FREITAS DO ROSARIO A P LAMB T SPENCE P	2012	J Inu-nunol2012，188，3：	1
15	Exercise and vascu- lar adaptation in asymptomatic humans显示文摘	GREEN I) J SPENCE A HALLIWILL J R	2011	Experimental physiology2011，96，2：	1
16	Optimization studies of carbon additives to negative active material for the purpose of extending the life of VRLA batteries in high-rate partial-state-of-charge operation显示文摘	Boden D P Loosemore D V Spence M A	2010	Journal of Power Sources2010，195，14：	1
17	Velocity structure of a gas hydrate reflector显示文摘	Singh B C Minshull T A Spence G D	1993	Sicence1993，260，：	1
18	Acupuncture increases noctur- nal melatonin secretion and reduces insomnia and anxiety:a prelimina- ry report 显示文摘	Spence DW Kayumov L Chert A	2004	J Neuropsychiatry Clin Neurosci2004，16，1：	1
19	Suppressors of cytokine signaling 2 and 3 diametrically control macrophage polarization显示文摘	Spence S Fitzsimons A Boyd CR	2013	Immunity2013，38，1：	1
20	Acupuncture increases nocturnal melatonin secretion and reduces insomnia and anxiety: a preliminary report显示文摘	Spence DW Kayumov L Chen A	2004	J Neuropsychiatry Clin Neurosci2004，16，1：	1

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