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| 1 | Impact of antiretroviral therapy on lipid metabolism of human immunodeficiency virus-infected patients: Old and new drugs显示文摘For human immunodeficiency virus(HIV)-infected patients, the 1990s were marked by the introduction of highly active antiretroviral therapy(HAART) representing a new perspective of life for these patients. The use of HAART was shown to effectively suppress the replication of HIV-1 and dramatically reduce mortality and morbidity, which led to a better and longer quality of life for HIV-1-infected patients. Apart from the substantial benefits that result from the use of various HAART regimens, laboratory and clinical experience has shown that HAART can induce severe and considerable adverse effects related to metabolic complications of lipid metabolism, characterized by signs of lipodystrophy, insulin resistance, central adiposity, dyslipidemia, increased risk of cardiovascular disease and even an increased risk of atherosclerosis. New drugs are being studied, new therapeutic strategies are being implemented, and the use of statins, fibrates, and inhibitors of intestinal cholesterol absorption have been effective alternatives. Changes in diet and lifestyle have also shown satisfactory results. | Joel da Cunha Luciana Morganti Ferreira Maselli Ana Carolina Bassi Stern Celso Spada Sérgio Paulo Bydlowski | 2015 | World Journal of Virology2015，4，2： | 9 |
| 2 | Antioxidant activity of the flavonoid hesperidin in chemical and biological systems显示文摘 | WILMSEN P K SPADA D S SALVADOR M | 2005 | Agric Food Chem2005，53，12： | 1 |
| 3 | Selectively-infective phage (SIP):a mechanistic dissection of a novel in vivo selection for protein-ligand interations显示文摘 | Krebber C Spada S Desplancq D | 1997 | J Mol Bio11997，268，： | 1 |
| 4 | Cancer precursor lesions in intact stomach Helicobacter pylori gastritis and in reected stomach gastritis显示文摘 | GIULIANI A SPADA S CORONA M | 2003 | J Exp Clin Cancer Res2003，22，3： | 1 |
| 5 | I disturbi del sonno in eta avanzata显示文摘 | Zanocchi M Ponzetto M Spada S | 1999 | Minerva Med1999，90，1112： | 1 |
| 6 | Selectively-infective phage (SIP): A mechanistic dissection of a novel in vivo selection for protein-ligand interactions 显示文摘 | Krebber C Spada S Desplancq D | 1997 | J Mol Biol1997，268，3： | 1 |
| 7 | Antioxidant activity of theflavonoid hesperidin in chemical and biological systems显示文摘 | Wilmsen P K Spada D S Salvador M | 2005 | Journal of Agricultural and Food Chemistry2005，53，12： | 1 |
| 8 | Pro up regulation: a diagn illicit use of oestrog ens in adult beef cattle显示文摘 | Divari S Mulasso C Spada F De Maria R gesterone receptor ostic tool for the Uslenghi F Cannizzo FT Brina N Biolatti B | 2011 | Tumour Biol2011，28，12： | 1 |
| 9 | Biliary dilatation secondary to lithiasis in a child affected by Langerhans' cell histiocytosis显示文摘 | Caruso S Miraglia R Spada M | 2009 | J Clin Ultrasound2009，37，： | 1 |
| 10 | Ischemic stroke and fibrinogen in the elderly显示文摘 | Spada RS Toscano G Chiarenza S | 2004 | Arch Gerontol Geriatr Suppl2004，，9： | 1 |
| 11 | Electrontransfer Photooxidation 3 : Detection of Radicalion Intermediates in the Cyanoaromatic sensitized Photooxidation of Transand Cisstilbene 显示文摘 | Lonnie T Spada Christopher S Foote | 1980 | J Am Chem Soc1980，102，1： | 1 |
| 12 | Ischemic stroke and fibrinogen in the elderly显示文摘 | Spada RS Toscano G Chiarenza S | 2004 | Arch Gerontol Geriatr Suppl2004，，9： | 1 |
| 13 | Antioxidant activity of the flavonoid hesperidin in chemical and biological systems显示文摘 | Wilmsen P K Spada D S Salvador M | 2005 | Agric Food Chem2005，53，12： | 1 |
| 14 | Antioxidant activity of the flavonoid hesperidin in chemical and biological systems显示文摘 | Wilmsen P K Spada D S Salvador M | 2005 | Journal of Agricultural and Food Chemistry2005，53，12： | 1 |
| 15 | Ischemic stroke and fibrinogen in the elderly显示文摘 | Spada RS Toscano G Chiarenza S | 2004 | Arch Gerontol Geriatr2004，9，4： | 1 |
| 16 | Antioxidant activity of the flavonoid hesperidin in chemical and biological systems显示文摘 | Wilmsen P K Spada D S Salvador M | 2005 | J Agric Food Chem2005，53，12： | 1 |
| 17 | Sleep disorders in the aged 显示文摘 | Zanocch iM Ponzetto M spada S | 1999 | Minerva Med1999，90，1112： | 1 |
| 18 | Ischemic stroke and fibrinogen in the elderly显示文摘 | Spada RS Toscano G Chiarenza S | 2004 | Arch Gerontol Geriatr2004，9，1： | 1 |
| 19 | Ischemic stroke and fibrinogen in the elderly显示文摘 | Spada RS Toscano G Chiarenza S | 2004 | Arch Gerontol Geriatr Suppl2004，，9： | 1 |
| 20 | Functional changes of human quadriceps muscle injured by eccentric exercise显示文摘 | Serrao F V Foerster B Spada S | 2003 | Braz J Med Biol Res2003，36，6： | 1 |
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