维普中文期刊产品整合服务
170篇 您的检索式:作者名="SOSA S"
    题名 作者 年代 出处 被引量
1Adjuvant therapy sparing in rectal cancer achieving complete response after chemoradiation显示文摘AIM:To evaluate the long-term results of conventional chemoradiotherapy and laparoscopic mesorectal excision in rectal adenocarcinoma patients without adjuvant therapy.METHODS:Patients with biopsy-proven adenocarcinoma of the rectum staged cT3-T4 by endoscopic ultrasound or magnetic resonance imaging received neoadjuvant continuous infusion of 5-fluorouracil for five weeks and concomitant radiotherapy.Laparoscopic surgery was planned after 5-8 wk.Patients diagnosed with ypT0N0 stage cancer were not treated with adjuvant therapy according to the protocol.Patients with ypT1-2N0 or ypT3-4 or N+were offered 5-fluorouracil-based adjuvant treatment on an individual basis.An external cohort was used as a reference for the findings.RESULTS:One hundred and seventy six patients were treated with induction chemoradiotherapy and 170underwent total mesorectal excision.Cancer staging of ypT0N0 was achieved in 26/170(15.3%)patients.After a median follow-up of 58.3 mo,patients withypT0N0 had five-year disease-free and overall survival rates of 96%(95%CI:77-99)and 100%,respectively.We provide evidence about the natural history of patients with localized rectal cancer achieving a complete response after preoperative chemoradiation.The inherent good prognosis of these patients will have implications for clinical trial design and care of patients.CONCLUSION:Withholding adjuvant chemotherapy after complete response following standard neoadjuvant chemoradiotherapy and laparoscopic mesorectal excision might be safe within an experienced multidisciplinary team.Xabier García-Albéniz Rosa Gallego Ralf Dieter Hofheinz Gloria Fernández-Esparrach Juan Ramón Ayuso-Colella Josep Antoni Bombí Carles Conill Miriam Cuatrecasas Salvadora Delgado Angels Ginés Rosa Miquel Mario Pagés Estela Pineda Verónica Pereira Aarón Sosa Oscar Reig Iván Victoria Luis Feliz Antonio María de Lacy Antoni Castells Iris Burkholder Andreas Hochhaus Joan Maurel 2014World Journal of Gastroenterology2014,20,42:5
2Topicalanti-inflammatory activity of extracts and compoundsfrom hypericum perforatum L显示文摘SOSA S PACE R BORNANCIN A 2007Journal ofPharmacy and Pharmacology2007,59,:1
3Medullary thyroid cancer: early detection and novel treatments显示文摘Roman S Mehta P Sosa J A 2009Curr Opin Oncol2009,21,1:1
4Prognostic factors for squanaous cell cancer of the parotid gland: an analysis of 2104 pa- tients 显示文摘Chen M M Roman S A Sosa J A 2015Head Neck2015,37,1:1
5Extracts and constituents of Lavandula multifida with topical anti-inflammatory activity phytomedicine显示文摘Sosa S Altinier G Politi M 2005Phytomedicine2005,12,4:1
6The misalignment of product architecture and organizational structure in complex product development显示文摘Sosa M Eppinger S Rowles C 2004Management Science2004,50,12:1
7Icdar2003 robust reading competitions 显示文摘Lucas S M Panaretos A Sosa L 2003Pattern Recognition2003,36,:1
8Electrical and piezoresistive properties of multi-walled carbon nanotube/polymer composite films aligned by an electric field显示文摘Oliva-Avile's A I Avile's F Sosa V 2011Carbon2011,49,9:1
9Pulsed electromagnetic fields induced femoral metaphyseal bone thickness changes in the rat显示文摘Marquez-Gamino S Sotelo F Sosa M 2008Bioelectromagnetics2008,29,5:1
10Culex flavivirus isolates from mosquitoes in Gua- temala显示文摘Morales-Betoulle M E Monzon Pineda M L Sosa S M 2008J Med Entomol2008,45,:1
11Focal bacterial nephritis masquerading as renal cell carcinoma:case report显示文摘Custovi(c) Z Sosa S 0,,01:1
12Chronic back pain is associat- ed with decreased prefrontal and thalamic gray matter density显示文摘Apkarian A V Sosa Y Sonty S 2004J Neurosci2004,24,10:1
13Have 2006 ATA practice guidelines affected the treatment of differentiated thyroid cancer in the United States? 显示文摘GOFFREDO P ROMAN S A SOSA J A 2013Thyroid2013,24,3:1
14Prognosis of medullary thyroidcarcinoma 显示文摘Roman S Lin R Sosa JA 2006Cancer2006,107,9:1
15Prevention of gliotic scar for-mation by NeuroGel allows partial endogenous repair of transected cat spinal cord显示文摘 Doan VD Sosa N 2004J Neurosei Res2004,75,2:1
16Surgical treatment of right coronary arteries with anomalous origin and slit ostium显示文摘GARCIA-RINALDI R SOSA J OLMEDA S 2004Ann Thorac Surg2004,77,:1
17The Mis- alignment of Product Architecture and Organiza tional Structure in Complex Product Development 显示文摘SOSA M EPPINGER S ROWLES C 2004Management Science2004,50,12:1
18Prevention of gliotic scar formation by NeuroGel al ows partial endogenous repair of transected cat spinal cord显示文摘Woerly S Doan VD Sosa N 0,,02:1
19Chronic back pain is associated with decreased prefrontal and thalamic gray matter density 显示文摘Apkarian A V Sosa Y Sonty S 2004J Neurosci2004,24,10:1
20Prognosis of medullary thyroid carci- noma: demographic, clinical, and pathological predictors of sur- vival in 1252 cases 显示文摘Roman S Lin R Sosa JA 2006Cancer2006,107,:1
返回顶部 每页显示:
共9页 首页 上一页 第1页 下一页 末页 /9 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费