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61篇 您的检索式:作者名="SOLIT DB"
    题名 作者 年代 出处 被引量
1Pulsatile administration of the epidermal growth factor receptor inhibitor gefitinib is significantly more effective than continuous dosing for sentitizing tumors to paclitaxel显示文摘Solit DB She Y Lobe J 2005clin cancer Res2005,11,:1
2In- hibition of heart shock protein in 90 function down-regulates Akt kinase and sensitizes tumors to taxol显示文摘Solit DB Basso AD Olshen AB 2003Cancer Res2003,62,9:1
3HsP90:a novel target for cancer therapy显示文摘Solit DB Rosen N 2006Curr Top Med Chem2006,6,11:1
4BRAF mutation predicts sensitivity to MEK inhibition 显示文摘Solit DB Garraway LA Pratilas CA 2006Nature2006,439,7074:1
5Akt forms an intracellular comJplex with heat shock Protein 90 (HSP90) and Cdc37 andis destabilized by Inhibitors of HSP90 funCtion 显示文摘Basso AD Solit DB Chiosis G 2002Biol Chem2002,277,39:1
6KRAS and BRAF:drug targets and predictive biomarkers显示文摘Vakiani E Solit DB 0,,02:1
7Development and application oi Hsp90 inhibitors显示文摘Solit DB Chiosis G 2008Drug Discov Today2008,13,12:1
8Inhibition of heat shock protein 90 function downregulatesAkt kinase and sensitizes tumors to Taxol 显示文摘Solit DB Basso AD Olshen AB 2003Cancer Res2003,63,:1
9A phase Ⅰ trial of intermittent high-dose gefitinib and fixed-dose docetaxel in patients with advanced solid tumors显示文摘Fury MG Solit DB Su YB 2007Cancer Chemother Pharmacol2007,59,:1
10KRAS and BRAF: drug targets and predictive biomarkers 显示文摘Vakiani E Solit DB 2011J Pathol2011,223,2:1
11Inhibition of heat shock protein 90 function down-regnlates Akt kinase and sensitizes tumors to Taxol显示文摘 Basso AD Olshen AB 2003Cancer Res2003,63,9:1
12T he BAD protein integrates survival signaling by egfr/mapk and PI 3 K/akt kinase pathways in pten-deficient tumor ceils 显示文摘She QB Solit DB Ye Q 2005Cancer Cell2005,8,4:1
13Phase 1I trial of 17- allylamino-17-demethoxygeldanamycin in patients with me-tastatic melanoma 显示文摘Solit DB Osman I Polsky D et ol 2008Clin Cancer Res2008,14,24:1
14KRAS and BRAF:drug targets and predic- tive biomarkers 显示文摘Vakiani E Solit DB 2011J Pathol2011,223,2:1
15Inhibition of heat shock protein 90 function down-regulates Akt kinase and sensitizes tu- mors to Taxol显示文摘Solit DB Basso AD Olshen AB Scher HI Rosen N 2003Cancer Res2003,,:1
16KRAS and BRAF: drug targets and predictive biomarkers显示文摘Vakiani E Solit DB 2011J Pathol2011,223,2:1
1717-Allylamino-17- demethoxy-geldanamycin induces the degradation of androgen receptor and HER-2/neu and inhibitor growth of prostate cancer xcnografts显示文摘Solit DB Zheng FF Drobnjak M 2002Clin Cancer Res2002,8,:1
18Therapeutic strategies for inhibiting oncogenic BRAF signaling显示文摘Halilovic E Solit DB 2008Curr Opin Pharmacol2008,8,4:1
19BRAF mutation predicts sensitivity to MEK inhibition显示文摘Solit DB Garraway LA Pratilas CA 2006Nature2006,439,7074:1
20Targeting the mitogen-activated pro- tein kinase pathway: physiological feedback and drug response 显示文摘PRATILAS CA SOLIT DB 2010Clin Cancer Res2010,16,:1
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