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50篇 您的检索式:作者名="SOLIT D"
    题名 作者 年代 出处 被引量
1Development and application of Hsp90 inhibitors显示文摘Solit D B Chiosis G 2008Drug Discov Today2008,13,12:1
2New Efficient Synthesis of ResorcJnylic Macrolides via Ynolides: Establishment of Cycloproparadicicol as Synthetically Feasible Preclinical Anticancer Agent Based on Hsp90 as the Target 显示文摘YANG Z GENG X SOLIT D 2004J Am Chem Soc2004,126,:1
3KRAS and BRAF: drug targets and pre- dictive biomarkers显示文摘Vakiani E Solit D B 2011J Pathol2011,223,2:1
4Inhibition of heat shock protein 90 function down-regulates Akt kinase and sensitizes tumors to Taxol显示文摘Solit D B Basso A D Olshen A B 2003Cancer Res2003,63,9:1
5Modulation of Hsp90 function by ansamycins sensitizes breast cance cells to chemotherapy-induced apoptosis in an RB-and schedule-dependent manner 显示文摘Munster PN Basso A Solit D 2001Clin Cancer Res2001,7,:1
6BRAF mutation predicts sensitivity to MEK inhibition 显示文摘SOLIT D B GARRAWAY L A PRATILAS C A 2005Nature2005,439,7074:1
7Inhi- bition of heat shock protein 90 function down-regu- lates Akt kinase and sensitizes rumors to taxol 显示文摘SOLIT D B BASSO A D OLSHEN A B 2003Cancer Res2003,63,9:1
8Akt forms an intracellular complex with heat shock protein 90(Hsp90)and Cdc37 and is destabilized by inhibitors of Hsp90 function显示文摘Basso A D Solit D B Chiosis G 2002J Biol Chem2002,277,39:1
9A phase I trial of intermittcnt high-dose gefitinib and fixed-dose docetaxel in patients with ad vanced solid tumors 显示文摘Fury M G Solit D B Su Y B 2007Cancer Chemother Pharmacol2007,59,4:1
10Phase 1I trial of 17- allylamino-17-demethoxygeldanamycin in patients with me-tastatic melanoma 显示文摘Solit DB Osman I Polsky D et ol 2008Clin Cancer Res2008,14,24:1
11Inhi- bition of heat shock protein 90 function down-regu- lates Akt kinase and sensitizes tumors to taxol 显示文摘SOLIT D B BASSO A D OLSHEN A B 2003Cancer Res2003,63,9:1
12BRAF mutation predicts sensitivity to MEK inhibition显示文摘SOLIT D B GARRAWAY L A PRATILAS C A 2005Nature2005,439,:1
13Pulsatile Administration of the Epi- dermal Growth Factor Receptor ]nhibitor Gditinib Is Significantly More Effective than Continuous Dosing for Sentitizing Tumors to Paclitaxel显示文摘Solit D B She Y Lobo J 2005Clin Cancer Res2005,11,5:1
14Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function显示文摘Basso A D Solit D B Chiosis G 2002J Biol Chem2002,277,39:1
15BRAF mutation predicts sensitivity to MEK inhibition 显示文摘SOLIT D B GARRAWAY L A PRATILAS C A 2005Nature2005,439,7074:1
16Inhibition of heat shock protein 90 function down-regulates Akt kinase and sensitizes tumors to Taxol显示文摘Solit D B Basso A D Olshen A B 2003Cancer Res2003,63,9:1
17BRAF mutation predicts sensitivity to MEK inhibition显示文摘Solit D B Garraway L A Pratilas C A 2005Nature2005,439,7074:1
18Imaging the pharmaeodynamics of HER2 degradation in response to Hsp90 inhibitors显示文摘SMITH-JONES P M SOLIT D B AKHURST T 2004Nature Biotechnology2004,22,6:1
19Drug discovery: How melanomas bypass new therapy 显示文摘Solit D Sawyers CL 2010Nature2010,468,7326:1
20Modulation of Hsp90 function by ansamycins sensitizes breast cancer cells to chemo therapy induced apoptosis in an RB- and schedule-dependent manner显示文摘MOnster PN Basso A Solit D 2001Clin Cancer Res2001,7,22:1
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