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| 1 | Mitigating osteonecrosis of the jaw(ONJ) through preventive dental care and understanding of risk factors显示文摘It is well established that alterations in phosphate metabolism have a profound effect on hard and soft tissues of the oral cavity. The present-day clinical form of osteonecrosis of the jaw(ONJ) was preceded by phosphorus necrosis of the jaw, ca. 1860. The subsequent removal of yellow phosphorus from matches in the early 20 th century saw a parallel decline in 'phossy jaw' until the early 2000 s, when similar reports of unusual jaw bone necrosis began to appear in the literature describing jaw necrosis in patients undergoing chemotherapy and concomitant steroid and bisphosphonate treatment. Today, the potential side effect of ONJ associated with medications that block osteoclast activity(antiresorptive) is well known, though the mechanism remains unclear and the management and outcomes are often unsatisfactory. Much of the existing literature has focused on the continuing concerns of appropriate use of bisphosphonates and other antiresorptive medications, the incomplete or underdeveloped research on ONJ, and the use of drugs with anabolic potential for treatment of osteoporosis. While recognizing that ONJ is a rare occurrence and ONJ-associated medications play an important role in fracture risk reduction in osteoporotic patients, evidence to date suggests that health care providers can lower the risk further by dental evaluations and care prior to initiating antiresorptive therapies and by monitoring dental health during and after treatment. This review describes the current clinical management guidelines for ONJ, the critical role of dental-medical management in mitigating risks, and the current understanding of the effects of predominantly osteoclast-modulating drugs on bone homeostasis. | Jason TWan Douglas MSheeley Martha JSomerman Janice SLee | 2020 | Bone Research2020，8，1： | 3 |
| 2 | Executioner caspase-3 ,-6, and -7 perform distinct, non-redundant roles during the demolition phase of apoptosiss显示文摘 | Slee EA Adrain C Maitin SJ | 2000 | Journal of Biological Chemistry2000，276，： | 1 |
| 3 | Sex and Age Differences in Victimi-zation and Conflict Resolution among Adolescents in a SouthAustralian School显示文摘 | Owens L Daly A Slee P | 2005 | Aggressive Behavior2005，31，： | 1 |
| 4 | Ordering the cytochrome c-initiated caspase cascade:hineratchical activation of caspases-2,-3,-6,-7,-8,and -10 in a caspase-9-dependent manner显示文摘 | Slee E A Harte M T Kluck R M | 1999 | J Cell Biol[J]1999，144，： | 1 |
| 5 | Serial killers:Ordering Caspase activation events in apoptosis显示文摘 | Slee EA Adrain C martin SJ | | 0，，： | 1 |
| 6 | The ASPP family:deciding between life and death after DNA damage显示文摘 | Slee EA Lu X | | 0，，2： | 1 |
| 7 | Cleavage of BID during cytotoxic drug and UV radiation-induced apoptosis occurs downstream of the point of Bcl-2 action and is catalysed by Caspase-3:a potential feedback loop for amplification of apoptosis-associated mitochondrial cytochrome c release显示文摘 | Slee E Keogh S Martin S | 2000 | Cell Death Differ2000，7，6： | 1 |
| 8 | 不同电池宽度半透明光伏窗天然采光分析显示文摘为了模拟不同太阳电池宽度对半透明光伏窗采光性能的影响,提出将非透光电池和透光玻璃间隙分开模拟的新方法,并使用实验数据验证新方法和模型的准确性。通过与实验结果的差异分析,采用新方法模拟所得到的照度和眩光可能性(DGP)的准确性均明显优于传统方法。采用新方法对太阳电池覆盖率相同但电池宽度分别为2.5、5.0以及7.5 mm的3种半透明光伏窗的天然采光特性进行模拟研究,并采用全天然采光时间百分比(DA)、有效天然采光照度(UDI)、天然光眩光指数(DGI)、眩光可能性(DGP)等指标对不同电池宽度光伏窗的采光和眩光性能进行对比分析。结果表明,随着电池宽度增加,室内平均DA和UDI逐渐减小,产生眩光的可能性增加,室内视觉舒适度下降。该文提出的方法使得研究不同电池宽度条件下半透明光伏窗的采光和眩光性能变为可能,且利用该方法得出相同电池覆盖率下最佳的电池宽度。 | 高静 彭晋卿 王韬宁 薛鹏 罗伊默 Eleanor SLee | 2022 | 太阳能学报2022，43，3： | 1 |
| 9 | A syndrome of leukonychia totalis and multiple sebaceous cysts显示文摘 | Slee JJ Wallman IS Goldblatt J | 1997 | Clin Dysmorphol1997，6，3： | 1 |
| 10 | Oxazolidinones,a new class of synthetic antibacterial agents:in vitro and in vivo activities of DuP 105 and DuP 721显示文摘 | Slee A M Wuonola M A McRipley R J | 1987 | Antimicrob Agents Chemother1987，31，11： | 1 |
| 11 | LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development 显示文摘 | GONG Y SLEE R B FUKAI N | 2001 | Cell2001，107，4： | 1 |
| 12 | Actin realignment and cofilin regulation are essential for barrier integrity during shear stress显示文摘 | Slee JB Lowe-Krentz LJ | 2013 | J Cell Biochem2013，，4： | 1 |
| 13 | The distribution of polycyclic aromatic hydrocarbons in surficial sediments of Sydney harbor,Australia显示文摘 | MCCREADY S SLEE D J BIRCH GF | | 0，，11： | 1 |
| 14 | Variations in exposure to mitomycin Clinan in vitro Colony-forming assay显示文摘 | SLEE PH TH J DE BRUIJIN EA | 1987 | Br J Cancer1987，54，： | 1 |
| 15 | LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development显示文摘 | Gong Y Slee RB Fukai N | 2001 | Cell2001，107，： | 1 |
| 16 | To die or not to die:how does p53 decide? 显示文摘 | SLEE E A O'CONNOR D J LU X | 2004 | Oncogene2004，23，16： | 1 |
| 17 | Cognitive-behavioural intervention for self-harm: Randomised controlled trial 显示文摘 | Slee N Garnefski N van der Leeden R | 2008 | Br J Psychiatry2008，192，3： | 1 |
| 18 | LDL receptor-related protein 5 (LRPS) affects bone accrual and eye development显示文摘 | Gong Y Slee RB Fukai N | 2001 | Cell2001，107，： | 1 |
| 19 | Ordering the cytochrome C-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner 显示文摘 | Slee EA Harte MT Kluck RM | 1999 | J Cell Biol1999，144，2： | 1 |
| 20 | The N-terminus of a novel isoform of human iASPP is required for its cytoplasmic localization显示文摘 | Slee E A Gillotin S Bergamaschi D | 2004 | Oncogene2004，23，56： | 1 |
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