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| 1 | Feasibility and accuracy of coronary imaging in elderly patients using the 64-row multi-detector computed tomography: a correlation study with conventional coronary angiography显示文摘Background Elderly patients generally have higher occurrence of coronary calcification, increased heart rate and difficulty with prolonged breath-holding. The aim of our study was to investigate the feasibility and accuracy of using 64-row multi-detector computed tomography (MDCT) in the assessment of coronary artery stenoses in elderly patients. Methods One hundred and fifty two patients with suspected or known coronary artery disease were divided into 4 groups according to their age (Group A: 40-49 years,n=34; Group B: 50-59 years, n=57; Group C: 60-69 years, n=48; Group D: 70 years and above; n=13). Coronary CT angiography (CTA) using a 64-row MDCT was performed and the findings were compared with that of conventional coronary angiography (CCA).Using axial images, multi-planar reconstructions (MPR) and maximum intensity projections (MIP), coronary segments of lumen diameter = 1.5mm were analyzed for the presence of significant stenosis (= 50% ). Results Percentages of poor image quality from coronary CTA preventing reliable correlations with CCA were 21%, 14%, 19% and 62% in Groups A to D respectively. Patients in Group D had significantly higher calcium scores compared with the other groups (P<0.001). In patients where CTA images were of acceptable quality, percentages of accurate correlations with CCA were 89.8%, 93.4%, 86.6% and 78.0% for Groups A to D respectively.There were no significant difference in serum creatinine, heart rate and contrast volume between the 4 groups. Conclusions The 64-row MDCT coronary angiography was less accurate and feasible for patients aged 70 years or above due to heavy coronary calcification and inability to perform a satisfactory breath-hold. However, a high diagnostic accuracy with the MDCT is possible in patients aged less than 70 years. | Chee Khoon LIEW Sze Piaw CHIN Tiong Kiam ONG Seyfarth Tobias Yean Yip FONG Choon Kiat ANG Houng Bang LIEW Rapaee ANNUAR Kui Hian SIM | 2006 | Journal of Geriatric Cardiology2006，3，1： | 4 |
| 2 | Chromosomal damages by ethanol and acetaldehyde in saccharomyces gel electrophoresis显示文摘 | Ristow H Seyfarth A Lochmann ER | 1995 | Mutation research1995，326，： | 2 |
| 3 | Antimicrobial susceptibility of Haemophilus parasuis and Histophilus somni from pigs and cattle in Denmark显示文摘 | Frank M Aarestrup Anne Mette Seyfarth ?ystein Angen | 2004 | Veterinary Microbiology2004，，2： | 1 |
| 4 | Energetic and peakpower advantages of series elastic actuators in an actuated pros-thetic leg for walking and running 显示文摘 | Grimmer M Eslamy M Seyfarth A | 2014 | Actuators2014，3，1： | 1 |
| 5 | Effect of a high loading dose of clopidogrel on platelet function in patients undergoing coronary stent placement显示文摘 | Muller I Seyfarth M Rudiger S | 2001 | Heart2001，85，1： | 1 |
| 6 | Portopulmonary hypertension 显示文摘 | Halank M Ewart R Seyfarth H J | 2006 | J Gastroentero12006，41，9： | 1 |
| 7 | Antifungal effect of high- and low-molecular-weight chitosan hydrochloride, carboxymethyl chitosan, chitosan oligosaccharide and N-acetyl-D-glucosamine against Candida albicans, Candida krusei and Candida glabrata显示文摘 | SEYFARTH F SCHLIEMANN S ELSNER P | 2008 | Int J Pharm2008，353，： | 1 |
| 8 | Antifungal effect ofhigh and low-molecular-weight chitosan hydrochloride,carboxy-methyl chitosan,chitosan oligosaccharide and N-acetyl-D-glu-cosamine against Candida albicans,Candida krusei and Candidaglabrata显示文摘 | Seyfarth F Schliemann S Elsner P | 2008 | Int J Pharm2008，353，12： | 1 |
| 9 | Paraneoplas- tic erythrocytosis associated with an inactivating point mu- tation of the von Hippel-Lindau gene in a renal cell carci- noma显示文摘 | Wiesener MS Seyfarth M Wanaecke C | 2002 | Blood2002，99，10： | 1 |
| 10 | The involution of man- nosebinding lectin 显示文摘 | SEYFARTH J GARRED P MADSEN H O | 2005 | Hum Mol Genet2005，14，19： | 1 |
| 11 | Effect of a high dose of clopidogrel on platelet function in patients undergoing coronary stent placement显示文摘 | Seyfarth M Rudiger S | 2001 | Heart2001，85，1： | 1 |
| 12 | The distribution of grooming and related behaviors among adult females vervet monkeys显示文摘 | Seyfarth RM | 1980 | Anim Behav1980，28，： | 1 |
| 13 | Mannose-binding lectin and its genetic variants显示文摘 | Garred P Larsen F Seyfarth J | 2006 | Genes lmmun2006，7，2： | 1 |
| 14 | Computer-assisted detection of pul-monary nodules:performance evaluation of an expert knowledge-based detection system in consensus reading with experienced and inexperi-enced chest radiologists 显示文摘 | Marten K Seyfarth T Auer F | 2004 | European Radiology2004，14，： | 1 |
| 15 | Antimicrobial susceptibility of Haemophilus parasuis and Histophilus somni from pigs and cattle in Denmark显示文摘 | Aarestrup F M Seyfarth A M Angen Q | 2004 | Vet Microbiol2004，101，2： | 1 |
| 16 | Trichophyton species of Arthroderma benhamiae – a new infectious agent in dermatology显示文摘 | Pietro Nenoff Silke Uhrla? Constanze Krüger Marcel Erhard Uta‐Christina Hipler Florian Seyfarth Jürgen Herrmann Tino Wetzig Wieland Schroedl Yvonne Gr?ser | 2014 | JDDG: Journal der Deutschen Dermatologischen Gesellschaft2014，，7： | 1 |
| 17 | PlA polymorphism platelet of glycoprotein Ⅲa and risk of restenosis after coronary stent placement显示文摘 | Schornig A Seyfarth M | 1999 | Circulation1999，99，8： | 1 |
| 18 | Factors influencing breath condensate volume 显示文摘 | GESSNER C KUHN H SEYFARTH HJ | 2001 | Pneumologie2001，55，9： | 1 |
| 19 | Unmasking melon by a complementary approach employing electron diffraction,solidstate NMR spectroscopy,and theoretical calculationsstructural characterization of a carbon nitride polymer显示文摘 | Lotsch B Y Doeblinger M Sehnert J Seyfarth L Senker J Oeckler O Schnick W | 2007 | Chemistry A Europe Journal2007，13，17： | 1 |
| 20 | Effect of a high loading dose of clopidogrel on platelet function in patients undergoing coronary stent placement显示文摘 | MUller l Seyfarth M Riidiger S | 2001 | Heart2001，85，1： | 1 |
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