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| 1 | High-intensity focused ultrasound ablation:An effective bridging therapy for hepatocellular carcinoma patients显示文摘AIM:To analyze whether high-intensity focused ultrasound(HIFU) ablation is an effective bridging therapy for patients with hepatocellular carcinoma(HCC).METHODS:From January 2007 to December 2010,49 consecutive HCC patients were listed for liver transplantation(UCSF criteria).The median waiting time for transplantation was 9.5 mo.Twenty-nine patients received transarterial chemoembolization(TACE) as a bringing therapy and 16 patients received no treatment before transplantation.Five patients received HIFU ablation as a bridging therapy.Another five patients with the same tumor staging(within the UCSF criteria) who received HIFU ablation but not on the transplant list were included for comparison.Patients were comparable in terms of Child-Pugh and model for end-stage liver disease scores,tumor size and number,and cause of cirrhosis.RESULTS:The HIFU group and TACE group showed no difference in terms of tumor size and tumor number.One patient in the HIFU group and no patient in the TACE group had gross ascites.The median hospital stay was 1 d(range,1-21 d) in the TACE group and two days(range,1-9 d) in the HIFU group(P < 0.000).No HIFU-related complication occurred.In the HIFU group,nine patients(90%) had complete response and one patient(10%) had partial response to the treatment.In the TACE group,only one patient(3%) had response to the treatment while 14 patients(48%) had stable disease and 14 patients(48%) had progressive disease(P = 0.00).Seven patients in the TACE group and no patient in the HIFU group dropped out from the transplant waiting list(P = 0.559).CONCLUSION:HIFU ablation is safe and effective in the treatment of HCC for patients with advanced cirrhosis.It may reduce the drop-out rate of liver transplant candidate. | Tan To Cheung Sheung Tat Fan See Ching Chan Kenneth SH Chok Ferdinand SK Chu Caroline R Jenkins Regina CL Lo James YY Fung Albert CY Chan William W Sharr Simon HY Tsang Wing Chiu Dai Ronnie TP Poon Chung Mau Lo | 2013 | World Journal of Gastroenterology2013，19，20： | 23 |
| 2 | Estimating liver weight of adults by body weight and gender显示文摘瞄准:为了为估计接枝的足够估计标准肝重量,为癌症在主要肝切除术在实时施主肝移植和残余肝缩放。方法:在这研究,体重和身高的人体测量的数据在 159 个实时的肝施主为与肝重量的关联被测试包括中间的肝的静脉经历了施主权利肝切除术。肝重量从在背表格获得的正确脑叶接枝重量被计算,在计算断层摄影术上由正确脑叶的比例划分了。结果:这些题目,所有汉语,有 35.8+/-10.5 年,和女性的吝啬的年龄到 118:41 的男比率。正确脑叶的吝啬的体积是 710.14+/-131.46 mL 并且在计算断层摄影术上占据了整个肝的 64.55%+/-4.47% 。正确脑叶称了 598.90+/-117.39 g,估计的肝重量是 927.54+/-168.78 g。当体重和身高受到多重逐步的线性回归分析时,身高被发现不足道。一样的体重的女性有稍微更低的肝重量。一个公式基于体重和性被导出:估计的标准肝重量(g)= 218 + BW (kg ) x 12.3 + 性 x 51 (R2 = 0.48 )( 女 = 0,男 = 1 ) 。基于这 159 个题目,的人体测量的数据肝重量用在白种人,日语,朝鲜语,和汉语上从研究导出的以前出版的公式被计算。所有公式与这个公式相比过高估计肝重量。日本公式为成年人过高估计估计的标准肝重量(ESLW ) 不到 60 kg。结论:对中国男性和女性适用的一个公式是可得到的。为单个赛跑的一个公式显得必要。 | See Ching Chan Chi Leung Liu Chung Mau Lo Banny K Lam Evelyn W Lee Yik Wong Sheung Tat Fan | 2006 | World Journal of Gastroenterology2006，12，14： | 22 |
| 3 | Modulation of graft vascular inflow guided by flowmetry and manometry in liver transplantation显示文摘BACKGROUND:Survival of the partial graft after living donor liver transplantation owes much to its tremendous regenerative ability.With excellent venous outflow capacity,a graft within a wide range of graft-to-standard-liver-volume ratios can cope with portal hypertension that is common in liver transplant recipients.However,when the ratio range is exceeded,modulation of graft vascular inflow becomes necessary for graft survival.The interplay between graft-to-standard-liver-volume ratio and portal pressure,in the presence of portosystemic shunt or otherwise,requires individualized modulation of graft portal and arterial inflows.Boosting of portal inflow by shunt ligation can be guided by transonic flowmetry,whereas muting of portal inflow by splenic artery ligation can be monitored by portal electronic manometry.METHOD:We describe four cases to illustrate the above.RESULTS:One patient had hepatic artery thrombosis resulting from splenic artery steal syndrome which was the sequela of small-for-size syndrome.Emergency splenic artery ligation and re-anastomosis of the hepatic artery successfully muted the portal inflow and boosted the hepatic arterial inflow.Another patient with portal vein thrombosis underwent thrombendvenectomy.Portal inflow was boosted with ligation of portosystemic shunt,which is often present in these patients with portal hypertension.The coexistence of splenic aneurysm and splenorenal shunt required ligation of both in the third patient.The fourth patient,with portal pressure and flow monitoring,avoided ligation of a coronary vein which became a main portal inflow after portal thrombendvenectomy.CONCLUSION:Management of graft inflow modulation guided selectively by transonic flowmetry or portal manometry was described. | See Ching Chan Chung Mau Lo Kenneth SH Chok William W Sharr Tan To Cheung Simon HY Tsang Albert CY Chan Sheung Tat Fan | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，6： | 5 |
| 4 | High-intensity focused ultrasound ablation as a bridging therapy for hepatocellular carcinoma patients awaiting liver transplantation显示文摘The scarcity of liver grafts in Asia leads to a significant dropout of patients from liver transplant waiting lists, particularly patients with hepatocellular carcinoma and a low model for end-stage liver disease score. In order to reduce dropping out, different bridging therapies are employed. We report the use of high-intensity focused ultrasound ablation as a bridging therapy for a patient with hepatocellular carcinoma of stage two and an extremely low platelet count (20×10 9 /L). The ablation was successful. Blood tests showed that his liver function was similar before and after the treatment. No adhesion was encountered in the liver transplantation performed six months later. | Tan To Cheung Kenneth SH Chok Regina CL Lo William W Sharr See Ching Chan Ronnie TP Poon Sheung Tat Fan Chung Mau Lo | 2012 | Hepatobiliary & Pancreatic Diseases International2012，11，5： | 3 |
| 5 | 矿用防爆锂离子电池电源安全设计影响因素研究显示文摘锂离子电池潜在的热失控风险及其可能引发的叠加效应对大型锂离子电池电源的安全设计提出了巨大挑战,因此在某些特殊应用领域,如煤矿井下爆炸性环境,大容量锂离子电池电源的使用依然存在诸多限制,难以普及。根据现有针对锂离子电池热失控行为的研究结论,在不进行充分的气体热力学和动力学分析的前提下,仅采用传统隔爆外壳对大容量锂离子电池电源进行防爆保护,存在隔爆外壳内部压力积聚的安全隐患。在分析现有研究工作的基础上,选用不同电池制造商生产的容量在72~280 A·h范围内的磷酸铁锂电池进行了热失控试验研究,全面分析了锂离子电池热失控过程中电池表面以及释放气体的温度、气体释放速度、释放气体在容器内产生的压力和释放气体的成分等相关参数。在此基础上,根据气体动力学和热力学特性,系统阐述了适用于煤矿井下爆炸性环境用可移动设备和后备电源等设备的锂离子电池电源在设计和制造过程中需要重点考虑的2个因素:①锂离子电池电源外壳内部的自由空间,②锂离子电池电源内部单体电池发生热失控事故时针对所释放气体的处理方法,并提出了必要的设计依据。本研究成果有望对爆炸性特殊环境用锂离子电池电源的防爆保护设计和安全完整性评估提供新的重要参考依据。 | SEE K W 王运鹏 张勇 张能 臧才运 | 2020 | 煤炭科学技术2020，48，11： | 3 |
| 6 | Retrohepatic vena cava deroofing in living donor liver transplantation for caudate hepatocellular carcinoma显示文摘The removal of tumor together with the native liver in living donor liver transplantation for hepatocellular carcinoma is challenged by a very close resection margin if the tumor abuts the inferior vena cava.This is in contrast to typical deceased donor liver transplantation where the entire retrohepatic inferior vena cava is included in total hepatectomy.Here we report a case of deroofing the retrohepatic vena cava in living donor liver transplantation for caudate hepatocellular carcinoma.In order to ensure clear resection margins,the anterior portion of the inferior vena cava was included.The right liver graft was inset into a Dacron vascular graft on the back table and the composite graft was then implanted to the recipient inferior vena cava.Using this technique,we observed the no-touch technique in tumor removal,hence minimizing the chance of positive resection margin as well as the chance of shedding of tumor cells during manipulation in operation. | See Ching Chan William W Sharr Tan To Cheung Albert CY Chan Simon HY Tsang Kenneth SH Chok Kin Chung Leung Chung Mau Lo | 2013 | Hepatobiliary & Pancreatic Diseases International2013，12，5： | 2 |
| 7 | Technigalva and other developments in batch hot - dip galvanizing显示文摘 | Kennon N F See J B | 1992 | JOM1992，44，1： | 1 |
| 8 | Microlaser made of disordered media显示文摘 | XU J Y SEEING E W | 2000 | Appl Phys Lett2000，76，21： | 1 |
| 9 | Individually CAD-CAM technique designed,bioresorbable 3-dimensional polycaprolactone framework for experimental reconstruction of craniofacial defects in the pig显示文摘 | ROHNER D HUTMACHER D W SEE P | 2002 | Mund Kiefer Gesichtschir2002，6，3： | 1 |
| 10 | Risk assessment of exposure to indoor aerosols associated with Chinese cooking显示文摘 | See S W Balasubramanian R | 2006 | Environmental Research2006，102，2： | 1 |
| 11 | Protection against oxidative stress-in- duced insulin resistance in rat L6 muscle cells by micrcomolar concentrations of alpha-lipoic acid 显示文摘 | Maddux BA See W Lawrence JC Jr | 2001 | Diabetes2001，50，2： | 1 |
| 12 | Protection against oxidative stress- induced insulin resistance in rat E6 muscle cells by mircomolar concentrations of alpha-lipoic acid 显示文摘 | MADDUX B A SEE W LAWRENCE J C | 2001 | Diabetes2001，50，2： | 1 |
| 13 | Recovery of Stem Cells from Cryopreserved Periodontal Ligament显示文摘 | See B M Miura M Sonoyama W | 2005 | J Dent Res2005，84，： | 1 |
| 14 | Radiological prognosticators of hepatocellular carcinoma treated by hepatectomy显示文摘BACKGROUND: Hepatectomy is the main curative treatment for hepatocellular carcinoma (HCC), but postoperative long- term survival is poor. Preoperative radiological features of HCC displayed by computed tomography or magnetic resonance imaging could serve as additional prognostic factors. This study aimed to identify preoperative radiological features of HCC that may be of prognostic significance in hepatectomy. METHODS: Ninety-two patients who underwent hepatectomy for HCC were included in this study. Preoperative radiological features including tumor number, size, location (peripheral, middle, central), portal vein invasion, hepatic vein invasion, and presence of pseudo-capsule were analyzed in relation to survival. RESULTS: With a median follow-up period of 41.7 months, the 1-, 3- and 5-year overall survival rates were 85%, 65% and 58%, respectively. Univariate analysis showed that portal vein invasion and absence of pseudo-capsule were significant prognostic factors for overall survival, while all the examined radiological features were prognostic factors for disease-free survival. Multivariate analysis for overall survival found no significant factor. On multivariate analysis for disease-free survival, patients who had tumors with portal vein invasion had poorer survival with a hazard ratio of 2.26 (95% CI, 1.05-4.91; P=0.038) and patients with single nodular HCC or pseudo-capsulated HCC had better survival with a hazard ratio of 0.50 (95% CI, 0.27-0.94; P=0.032) and 0.38 (95% CI, 0.14-0.99; P=0.048), respectively. CONCLUSIONS: Demonstrable pseudo-capsule of HCC and solitary HCC on imaging and absence of portal vein invasionare features associated with better disease-free survival after hepatectomy. These features may guide treatment planning for HCC. | Kevin KW Chu See Ching Chan Sheung Tat Fan Kenneth SH Chok Tan To Cheung William W Sharr Albert CY Chan Chung Mau Lo | 2012 | Hepatobiliary & Pancreatic Diseases International2012，11，6： | 1 |
| 15 | Symptomatic coronary obstruction due to Kawasaki disease in an adult 显示文摘 | Codispoti C Boyd S Sees D Conner W | 2008 | Ann Thorac Surg2008，85，3： | 1 |
| 16 | Note, China' s Latest 'Threat' to the United States: The Failed CNOOC - UNO- CAL Merger and Its Implications for Exon - Florio and CFIUS 显示文摘 | See Casselman Joshua W | 2007 | Indiana International & Comparative Law Review2007，17，： | 1 |
| 17 | Chemical characteris-tics of fine particles emitted from different gas cooking meth-ods显示文摘 | SEE S W BALASUBRAMANIAN R | 2008 | Atmospheric Environment2008，42，39： | 1 |
| 18 | Characterization of fine particle emissions from incense burning显示文摘 | See S W Balasubramanian R | 2011 | Building and Environment2011，46，： | 1 |
| 19 | Subpixel microscopic deformation analysis using correlation and artificial neutral net- works 显示文摘 | P1TTER M C SEE C W SOMEKH M G | 2001 | Optics Express2001，8，6： | 1 |
| 20 | Risk assessment of exposure to indoor aerosols associated with Chinese cooking显示文摘 | See S W Balasubramanian R | | 0，，： | 1 |
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