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| 1 | Adenoid cystic carcinoma of breast: Recent advances显示文摘Adenoid cystic carcinoma(ACC) of the breast is a rare special subtype of breast cancer characterized by the presence of a dual cell population of luminal and basaloid cells arranged in specific growth patterns. Most breast cancers with triple-negative, basal-like breast features(i.e., tumors that are devoid of estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 expression, and express basal cell markers) are generally high-grade tumors with an aggressive clinical course. Conversely, while ACCs also display a triple-negative, basal-like phenotype, they are usually low-grade and exhibit an indolent clinical behavior. Many discoveries regarding the molecular and genetic features of the ACC, including a specific chromosomal translocation t(6;9) that results in a MYB-NFIB fusion gene, have been made in recent years. This comprehensive review provides our experience with ACC of the breast, as well as an overview of clinical, histopathological, and molecular genetic features. | Kosuke Miyai Mary R Schwartz Mukul K Divatia Rose C Anton Yong Wook Park Alberto G Ayala Jae Y Ro | 2014 | World Journal of Clinical Cases2014，2，12： | 16 |
| 2 | Four-year follow-up of endoscopic gastroplication for the treatment of gastroesophageal reflux disease显示文摘AIM:To evaluate the long-term effect of Endocinch treatment for gastroesophageal reflux disease(GERD).METHODS:After unblinding and crossover,50 patients(32 males,18 females; mean age 46 years) with pH-proven chronic GERD were recruited from an initial randomized,placebo-controlled,single-center study,and included in the present prospective open-label follow-up study.Initially,three gastroplications using the Endocinch device were placed under deep sedation in a standardized manner.Optional retreatment was offered in the first year with 1 or 2 extra gastroplications.At baseline,3 mo after(re) treatment and yearly proton pump inhibitor(PPI) use,GERD symptoms,quality of life(QoL) scores,adverse events and treatment failures(defined as:patients using > 50% of their baseline PPI dose or receiving alternative antireflux therapy) were assessed.Intention-to-treat analysis was performed.RESULTS:Median follow-up was 48 mo [interquartile range(IQR):38-52].Three patients were lost to follow-up.In 44% of patients retreatment was done after a median of 4 mo(IQR:3-8).No serious adverse events occurred.At the end of follow-up,symptom scores and4 out of 6 QoL subscales were improved(all P < 0.01compared to baseline).However,80% of patients required PPIs for their GERD symptoms.Ultimately,64% of patients were classified as treatment failures.In 60% a post-procedural endoscopy was carried out,of which in 16% reflux esophagitis was diagnosed.CONCLUSION:In the 4-year follow-up period,the subset of GERD patients that benefit from endoscopic gastroplication kept declining gradually,nearly half opted for retreatment and 80% required PPIs eventually. | Matthijs P Schwartz J Rieneke C Schreinemakers André J P M Smout | 2013 | World Journal of Gastrointestinal Pharmacology and Therapeutics2013，4，4： | 4 |
| 3 | Subepicardial endothelial cells invade the embryonic ventricle wall to form coronary arteries显示文摘冠的动脉把血流动带到心肌肉。理解冠的动脉的发展程序提供卓见进冠的动脉疾病的治疗。多重来源被描述了为包括 proepicardium,湾穴 venosus (SV ) ,和心内膜贡献冠的动脉。然而,冠的容器的发展起源仍然在强烈学习下面。我们为学习冠的开发生产了一个新基因工具,一只 AplnCreER 老鼠在开发冠的容器明确地衬里 recombinase,它表示可诱导的 Cre。冠的开发和 AplnCreER 命运跟踪的预定正式就职的定量分析证明 subepicardial endothelial 房间(EC ) 的子孙两个都入侵紧缩的心肌层形成冠的动脉并且在表面上留下生产静脉。我们发现这些 subepicardial EC 是 intramyocardial 的主要来源在发展中的心的冠的容器。在 vitro 将生物的活组织移植于培养基中培养,试金显示这些 subepicardial EC 的多数从 SV 和中庭的心内膜,然而并非从室的心内膜产生。Apln 积极的房间的同种细胞的分析显示单个 subepicardial EC 同等地作出贡献到冠的动脉和静脉。一起,这些数据建议 subepicardial EC 是 intramyocardial 的主要来源在室的冠的动脉墙,和那冠的动脉和静脉在发展中的心有普通起源。 | Xueying Tian Tianyuan Hu Hui Zhang Lingjuan He Xiuzhen Huang Qiaozhen Liu Wei Yu Liang He Zhongzhou Yang Zhen Zhang Tao P Zhong Xiao Yang Zhen Yang Yan Yan Antonio Baldini Yunfu Sun Jie Lu Robert J Schwartz Sylvia M Evans Adriana C Gittenberger-de Groot Kristy Red-Horse Bin Zhou | 2013 | Cell Research2013，23，9： | 3 |
| 4 | 经验证的多基因风险评分对中青年人冠状动脉粥样硬化性心脏病长期风险的预测作用显示文摘本文旨在了解先前获得的多基因风险评分(polygenic risk scores, PRS)对冠状动脉粥样硬化性心脏病(冠心病)长期风险的预测效用及其超越传统危险因素的附加价值,为预防策略提供信息。方法:纳入Framingham后代研究(Framingham offspring study, FOS)和社区动脉粥样硬化风险(atherosclerosis risk in communities, ARIC)研究中年龄20~59岁无冠心病的成年人数据进行分析。 | Khan SS Page C Wojdyla DM Schwartz YY Greenland P Pencina MJ 刘青(译) 郑武洪(审校) | 2022 | 中华高血压杂志2022，30，12： | 2 |
| 5 | 'Reductiveozonolysis' via a new fragmentation of carbonyl oxides 显示文摘 | Schwartz C RaibleJ MottK etal | 2006 | Tetrahedron2006，62，10： | 1 |
| 6 | Robust Transient Signal Detection Using the Oversampled Gabor Representation显示文摘 | Lee N Schwartz S C | 1995 | IEEE Transactions on Signal Processing1995，43，6： | 1 |
| 7 | Specialization as strategy for business incubators: An assessment of the central german multi-media center 显示文摘 | SCHWARTZ M HORNYCH C | 2008 | Technovation2008，，2： | 1 |
| 8 | Wide band imped- ance matching: H∞ performance bounds显示文摘 | SCHWARTZ D F ALLEN J C | 2004 | IEEE Transactions on Circuit and Systems--II: Express Briefs2004，51，7： | 1 |
| 9 | Pluripotency of mesenchymal stem cells derived from adult marrow显示文摘 | Jiang Y Jahagirdar B N Reinhardt R L Schwartz R E Keene C D Ortiz Gonzalez X R | 2002 | Nature2002，418，： | 1 |
| 10 | Contribution of technical materials to the mobile fraction of metals in urban soils in Marrakech (Morocco) 显示文摘 | Khalil H E Schwartz C Elhamiani O | 2008 | Journal of Soils and Sediments2008，8，1： | 1 |
| 11 | 13C andl5N natural abundance of the soil microbial biomass显示文摘 | Dijkstra P Ishizu A Doucett R Hart S C Schwartz E Menyailo O V Hungate B A | 2006 | Soil Biology & Biochemistry2006，38，： | 1 |
| 12 | Identification of a long QT Syndrome molecular defect in drug induced torsade depointes显示文摘 | Napolitano C Priori SG Schwartz PJ | 1997 | Circulation1997，96，1： | 1 |
| 13 | Investment under uncertainty in information technology:acquisition and development projects显示文摘 | Schwartz E S Zozaya C | 2003 | Management Science2003，49，1： | 1 |
| 14 | Ubiquitin-mediated degradation of cellular proteins in health and disease显示文摘 | Aaron C Schwartz AL | 2002 | Hepatology2002，35，1： | 1 |
| 15 | A mutant form of maltose-binding protein of Escherichia coli deficient in its interaction with the bacteriophage lambda receptor protein显示文摘 | Bavoil P Wandersman C Schwartz M | 1983 | Bacteriology1983，155，： | 1 |
| 16 | Novel 3-dimensional placental measurements in early pregnancy as predictors of adverse pregnancy outcomes 显示文摘 | Schwartz N Coletta J Pessel C | 2010 | J Ultrasound Med2010，29，8： | 1 |
| 17 | A coarse grain modet for DNA显示文摘 | Knotts IV T A Rathore N Schwartz 9 C | 2007 | The Journal of chemical physics2007，126，08： | 1 |
| 18 | The Jervell and Lange-Nielsen syndrome: natural history, molecular basis, and clinical outcome显示文摘 | Schwartz PJ Spazzolini C Crotti L | 2006 | Circulation2006，113，6： | 1 |
| 19 | American Socie- ty o Clinical Oncology / College o显示文摘 | Wolff A C Hammond M E Schwartz J N | 2007 | Arch Pathol Lab Med2007，131，1： | 1 |
| 20 | Peptidase-deficient mutants of Escherichia coli显示文摘 | MILLER C G SCHWARTZ G | 1978 | Journal of Bacteriology1978，135，2： | 1 |
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