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90篇 您的检索式:作者名="SCHAFFNER P"
    题名 作者 年代 出处 被引量
1被激光损伤软骨释放的凋亡因子诱导软骨细胞凋亡的研究显示文摘目的探讨组织损伤后凋亡信号怎样促进细胞的死亡进程。方法在激光照射后猪软骨块置培液中,在不同时间(3、6、9、12、24 h)收集的培液,即实验条件培养液(TCM),从未经激光照射的软骨块培液取得的为对照条件培养液(CCM)。软骨块继续培养28 d,用聚焦显微镜评价其受损区的进展。分离的软骨细胞单层放于 TCM、CCM 或正常培养液(NM)培养,阳性对照组单层细胞经紫外线照射10 min 后继续用正常培养液培养,培养24 h 后,收集细胞并用荧光标记物染色,经流式细胞仪分析。结果所有经 TCM 培养的细胞显现半胱氨酸蛋白水解酶(caspase)-3阳性、CMXRos 和一氧化氮信号减少或失去;经 CCM 或 NM 培养的细胞显现 caspase-3阴性、CMXRos 和一氧化氮信号完好;阳性对照组细胞显现 Caspase-3和 CMXRos 均阳性、一氧化氮信号减少或失去,代表处于凋亡早期的细胞。不同 TCM 浓度(100%、50%、25%、12.5%)和时间(0.5、1、3、9、12 h)对细胞作用后,所有细胞均呈现 caspase-3阳性、CMXRos 和一氧化氮信号减少或失去。结论激光照射受损软骨释放凋亡因子,可诱导单层细胞死亡。郑敏 Grogan SP Schaffner T Mainil-Varlet P 2007中华医学杂志2007,87,21:3
2Early and late outcome of operated and non-operated acute dissection of the descending aorta显示文摘Gysi J Schaffner T Mohaesi P 1997Eur J Cardiothorac Surg1997,11,6:1
34-Nonylphenol in sewage sludge: accumulation of toxic metabolites from nonionie surfaetants显示文摘GIGER W BRUNNER P H SCHAFFNER C 1984Science1984,225,4662:1
4Regulated expression of platelet factor 4 in human monocytes-role of PARs as a quantitatively important monocyte activation pathway 显示文摘SCHAFFNER A RHUN P SCHOEDON G 2005J Leukoc Biol2005,78,1:1
5Predictive microbiology: where are we, and where are we going 显示文摘SCHAFFNER D W LABUZA T P 1997Food Technol1997,51,4:1
6Dental erosion in a population of Swiss adults显示文摘Lussi A schaffner M Hotz P 1991Community of Dentistry and Oral Epidemiology1991,19,:1
7Comparison of diester waste treatment by conventional and bipolar electrodialysis显示文摘Schaffner F Pontaher P Y Sanchez V 2004Desalination2004,170,2:1
8Porcine dendritic cells generated in vitro: morphological, phenotypic and functional properties 显示文摘Carrasco C P Rigden R C Schaffner R 2001Immunology2001,104,:1
9Phosphine-catalyzed synthesis of,6-substituted,2-pyrones:Manifestation of E/Z-isomerism in the zwitterionic intermediate显示文摘Zhu X F Schaffner A P Li R C Kwon O 0,,:1
10Acetylcholine receptor ag-gregation at nerve-muscle contacts in mammalian cul-tures:induction by ventral spinal cord neurons is specif-ic to axons显示文摘Dutton E K Uhm C S Samuelsson S J Schaffner A E Fitzgerald S C Daniels M P 1995J Neurosci1995,15,:1
11Structure and function of RGD peptides involved in bone biology 显示文摘Schaffner P Dard MM 2003Cell Mol Life Sci2003,60,1:1
12Differ-ential effects of Aureococcus anophagefferens isolates ( ' browntide” ) in unialgal and mixed suspensions on bivalve feeding显示文摘BRICEU V M MACQUARRIE S P SCHAFFNER R A 2001Marine Biology2001,139,4:1
13Early and late outcome of operated and non-operated acute dissection of the descending aorta显示文摘Gysi J Schaffner T Mohacsi P 1997Eur J of Cardo-thoracic Surgery1997,11,6:1
14Early and late outcome of operatedand non-operated acute dissection of the descending aorta 显示文摘Gysi J Schaffner T Mohacsi P 1997Euro J Cardiothorao Surg1997,11,61:1
15The influence of DISI engine operating parameters on particle number emissions显示文摘SABATHIL D KOENIGSTEIN A SCHAFFNER P 2011SAE Paper2011,,:1
16Comparison of dlester waste treatment by conventional andbipolar electrodialysis 显示文摘Schaffner F Pontalier P Y Sanchez V 2004Desalination2004,170,2:1
17Early and late outcome of operated and non-operated acute dissection of the descending aorta显示文摘Gysi J Schaffner T Mohacsi P 1997Eur J Cardiothorac Surg1997,11,6:1
18Comparison of diester waste treatment by conventional and bipolar electrodialysis 显示文摘Schaffner F Pontalier P Y Sanehez V 2004Desalination2004,170,2:1
19Genomic surveillance elucidates Ebola virus origin and transmission during the 2014outbreak显示文摘Gire S K Goba A Andersen K G Sealfon R S Park D J Kanneh L Jalloh S Momoh M Fullah M Dudas G Wohl S Moses L M Yozwiak N L Winnicki S Matranga C B Malboeuf C M Qu J Gladden A D Schaffner S F Yang X Jiang P P Nekoui M Colubri A Coomber M R Fonnie M Moigboi A Gbakie M Kamara F K Tucker V Konuwa E Saffa S Sellu J Jalloh A A Kovoma A Koninga J Mustapha I Kargbo K Foday M Yillah M Kanneh F Robert W Massally J L Chapman S B Bochicchio J Murphy C Nusbaum C Young S Birren B W Grant D S Scheiffelin J S Lander E S Happi C Gevao S M Gnirke A Rambaut A Garry R F Khan S H Sabeti P C 2014Science2014,345,6202:1
20Endocarditis in intravenous drug addicts and HIV infcted patients:possibilities and limitatious of surgical treatment显示文摘Carrel T Schaffner A Vogt P 1993J Heart Valve Dis1993,2,2:1
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