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| 1 | 无位置传感器开关磁阻电机初始位置检测方法显示文摘以开关磁阻电机(switched reluctance machine,SRM)的非线性模型为仿真平台,给出一种用于检测SRM转子初始角位置的新方法,向电机各相注入一定幅值的方波电压,利用相电流峰值及其与转子角位置之间的解析关系式求出转子的初始角位置,从而实现转子处于任何位置时的快速无反转起动。同时,对该位置检测方法的鲁棒性进行了研究,得到了预估相的选取原则。以一台三相6/4极SRM为对象进行了相关实验,实验结果验证了该位置检测方法的可行性及预估相选取原则的正确性。 | 刘卫国 宋受俊 Uwe Schafer | 2009 | 中国电机工程学报2009，29，24： | 21 |
| 2 | Redundant CAMTA Transcription Factors Negatively Regulate the Biosynthesis of Salicylic Acid and N-Hydroxypipecolic Acid by Modulating the Expression of SARD1 and CBP60g显示文摘Two signal molecules, salicylic acid (SA) and N-hydroxypipecolic acid (NHP), play critical roles in plant immunity. The biosynthetic genes of both compounds are positively regulated by master immune-regulating transcription factors SARD1 and CBP60g. However, the relationship between the SA and NHP pathways is unclear. CALMODULIN-BINDING TRANSCRIPTION FACTOR 1 (CAMTA1), CAMTA2, and CAMTA3 are known redundant negative regulators of plant immunity, but the underlying mechanism also remains largely unknown. In this study, through chromatin immunoprecipitation and electrophoretic mobility shift assays, we uncovered that CBP60g is a direct target of CAMTA3, which also negatively regulates the expression of SARD1, presumably via an indirect effect. The autoimmunity of camta3-1 is suppressed by sard1 cbp60g double mutant as well as ald1 and fmo1, two single mutants defective in NHP biosynthesis. Interestingly, a suppressor screen conducted in the camta1/ 2/ 3 triple mutant background yielded various mutants blocking biosynthesis or signaling of either SA or NHP, leading to nearly complete suppression of the extreme autoimmunity of camta1/ 2/ 3, suggesting that the SA and NHP pathways can mutually amplify each other. Together, these results reveal that CAMTAs repress the biosynthesis of SA and NHP by modulating the expression of SARD1 and CBP60g, and that the SA and NHP pathways are coordinated to optimize plant immune response. | Tongjun Sun Jianhua Huang Yan Xu Vani Verma Beibei Jing Yulin Sun Alberto Ruiz Orduna Hainan Tian Xingchuan Huang Shitou Xia Laurel Schafer Reinhard Jetter Yuelin Zhang Xin Li | 2020 | Molecular Plant2020，13，1： | 5 |
| 3 | 脂肪乳对内毒素诱导急性肺损伤小鼠的干预作用显示文摘目的比较以橄榄油为主的脂肪乳Clinoleic20%○R和豆油为主的脂肪乳Lipoven20%○R对脂多糖(LPS)诱导急性肺损伤(ALI)小鼠炎症反应的作用。方法雄性Balb/C小鼠按随机数字表法分为生理盐水(NaCl)、Clino和Lipo3组。用微量泵分别向3组小鼠泵入质量分数为0.9%的NaCl、20%Clinoleic和20%Lipoven,并在进行取血和肺泡灌洗前8h和24h向气管内喷洒LPS制备ALI模型。观察3组小鼠LPS诱导8h和24h时的存活率、肺组织湿/干重比、支气管肺泡灌洗液(BALF)中白细胞计数、肿瘤坏死因子-α(TNF-α)、巨噬细胞炎性蛋白-2(MIP-2)、肺组织髓过氧化物酶(MPO)活性及血清花生四烯酸(AA)、油酸、亚油酸含量。结果LPS诱导后可引起BALF中白细胞计数、TNF-α、MIP-2,肺组织MPO活性、W/D比例及血清AA水平显著升高。Lipoven显著降低ALI小鼠24h后的存活率(P均<0.01),而Clino组与NaCl组之间差异无显著性;肺组织MPO活性在24h后两个脂肪乳组明显高于NaCl组(P均<0.01),而两个脂肪乳之间差异无显著性。注射ALI8h后,Lipo组BALF中MIP-2和血清AA均较NaCl组和Clino组升高,24h后BALF中白细胞、TNF-α、AA水平也均显著高于NaCl组和Clino组(P均<0.01);而肺组织水肿程度和油酸、亚油酸含量在3组间比较差异均无显著性。结论Lipoven20%加重ALI小鼠的炎症反应,降低实验动物的存活率,可能与其增加AA产生有关;而Clinoleic20%对炎症反应的影响较轻。 | 毕铭华 王宝恩 Martina Schafer Konstantin Mayer 张淑文 李敏 王惠吉 | 2006 | 中国危重病急救医学2006，18，12： | 5 |
| 4 | Thermal Reversion of Plant Phytochromes显示文摘Phytochromes are red/far-red reversible photoreceptors essential for plant growth and development.Phytochrome signaling is mediated by the physiologically active far-red-absorbing Pfr form that can be inactivated to the red-absorbing Pr ground state by light-dependent photoconversion or by light-independent thermal reversion,also termed dark reversion.Although the term“dark reversion”is justified by historical reasons and frequently used in the literature,“thermal reversion”more appropriately describes the process of light-independent but temperature-regulated Pfr relaxation that not only occurs in darkness but also in light and is used throughout the review.Thermal reversion is a critical parameter for the light sensitivity of phytochrome-mediated responses and has been studied for decades,often resulting in contradictory findings.Thermal reversion is an intrinsic property of the phytochrome molecules but can be modulated by intra-and intermolecular interactions,as well as biochemical modifications,such as phosphorylation.In this review,we outline the research history of phytochrome thermal reversion,highlighting important predictions that have been made before knowing the molecular basis.We further summarize and discuss recent findings about the molecular mechanisms regulating phytochrome thermal reversion and its functional roles in light and temperature sensing in plants. | Cornelia Klose Ferenc Nagy Eberhard Schafer | 2020 | Molecular Plant2020，13，3： | 4 |
| 5 | 脂肪乳肠外营养在危重症患者中的应用显示文摘 | 毕铭华 李敏 王惠吉 张淑文 王宝恩 Martina Schafer Konstantin Mayer | 2006 | 中国危重病急救医学2006，18，10： | 4 |
| 6 | The peroxisome proliferator-activated receptor-α (PPAR-α) agonist, AVE8134, attenuates the progression of heart failure and increases survival in rats显示文摘 | Wolfgang LINZ Paulus WOHLFART Manuel BAADE Kristin BREITSCHOPF EugenFALK Hans-Ludwig SCHAFER Martin GERL Werner KRAMER Hartmut RUTTEN | 2009 | Acta Pharmacologica Sinica2009，30，7： | 3 |
| 7 | 斜元件在三峡水轮发电机设计中的应用显示文摘重点介绍了斜元件设计与传统结构的不同特点 ,并详细叙述三峡项目水轮发电机定子机座、转子支架和上。 | 刘公直 李志和 Axel Fuerst Daniel Schafer | 2002 | 中国三峡建设2002，9，3： | 3 |
| 8 | 根管冲洗显示文摘在根尖周炎的病例中.微生物定植根管系统。目前.通过机械的方法尚不能将根管内的所有微生物彻底清除。因此.要想根除根管内的感染,冲洗是十分必要的。本文对最常用的冲洗剂的不同作用以及它们之间的相互作用进行了讨论.并对临床提出指导性建议。要减少根管内的微生物.至少应用两种不同的冲洗剂才能获得最好的效果。 | Edgar Schafer 刘洋(译) 岳林(审) | 2010 | 中国口腔医学继续教育杂志2010，13，4： | 3 |
| 9 | 持续微型化:紧凑空间内使用力传感器系统保证质量显示文摘压电式力传感器的紧凑设计、高精度、高过载和宽范围的测量能为制造商提供100%的质量保证,从而在这竞争激烈,不断微型化的市场脱引而出。 | Stefan Schafer | 2016 | 电子产品世界2016，23，2： | 3 |
| 10 | Degradation of intestinal mRNA:A matter of treatment显示文摘AIM: To characterize the influence of location, species and treatment upon RNA degradation in tissue samples from the gastrointestinal tract. METHODS: The intestinal samples were stored in different medium for different times under varyingconditions: different species(human and rat), varying temperature(storage on crushed ice or room temperature), time point of dissection of the submucous-mucous layer from the smooth muscle(before or after storage), different rinsing methods(rinsing with Medium, PBS, RNALater or without rinsing at all) and different regions of the gut(proximal and distal small intestine, caecum, colon and rectum). The total RNA from different parts of the gut(rat: proximal and distal small intestine, caecum, colon and rectum, human: colon and rectum) and individual gut layers(muscle and submucosal/mucosal) was extracted. The quality of the RNA was assessed by micro capillary electrophoresis. The RNA quality was expressed by the RNA integrity number which is calculated from the relative height and area of the 18 S and 28 S RNA peaks. From rat distal small intestine q PCR was performed for neuronal and glial markers.RESULTS: RNA obtained from smooth muscle tissue is much longer stable than those from submucosal/mucosal tissue. At RT muscle RNA degrades after one day, on ice it is stable at least three days. Cleaning and separation of gut layers before storage and use of RNALater, maintains the stability of muscle RNA at RT for much longer periods. Different parts of the gut show varying degradation periods. RNA obtained from the submucosal/mucosal layer always showed a much worse amplification rate than RNA from muscle tissue. In general RNA harvested from rat tissue, either smooth muscle layer or submucosal/mucosal layer is much longer stable than RNA from human gut tissue, and RNA obtained from smooth muscle tissue shows an increased stability compared to RNA from submucosal/mucosal tissue. At RT muscle RNA degrades after one day, while the stability on ice lasts at least three days. Cleaning and separation of gut layers before storage and use of RNALater, maintains the stability of muscle RNA at RT for much longer periods. Different parts of the gut show varying degradation periods. The RNA from muscle and submucosal/mucosal tissue of the proximal small intestine degrades much faster than the RNA of distal small intestine, caecum or colonwith rectum. RNA obtained from the submucosal/mucosal layer always showed a much more reduced amplification rate than RNA from muscle tissue [β-Tubulin Ⅲ for muscle quantification cycle(Cp): 22.07 ± 0.25, for β-Tubulin Ⅲ submucosal/mucosal Cp: 27.42 ± 0.19].CONCLUSION: Degradation of intestinal m RNA depends on preparation and storage conditions of the tissue. Cooling, rinsing and separating of intestinal tissue reduce the degradation of m RNA. | Sabine Heumüller-Klug Carsten Sticht Karin Kaiser Elvira Wink Cornelia Hagl Lucas Wessel Karl-Herbert Schafer | 2015 | World Journal of Gastroenterology2015，21，12： | 2 |
| 11 | 球铁升降机铸件铸造工艺计算机模拟优化设计显示文摘通过对用湿砂型生产的球铁升降机铸件凝固组织和固相转变的模拟,预测了其凝固过程、组织和性能情况,并通过计算机模拟对原工艺方案进行了优化。新工艺只有一个内浇道、两个发热冒口,并且没有采用冷铁,生产出的铸件没有缩孔、缩松和夹渣缺陷,工艺出品率也从最初的50%提高到了65%。 | Richard hagaard Wilfried Schafer Erik Hepp Christian Kleeberg Jan Franke 余永吉 | 2010 | 现代铸铁2010，30，2： | 2 |
| 12 | 用于脂肪移植及脂肪干细胞分离获取与处理技术的对比显示文摘背景与目的脂肪获取和处理技术的差异可能会影响脂肪移植的成功率。本研究利用裸鼠模型,对比不同处理方法获取的脂肪移植物的性质,并评估移植脂肪组织中存活组织的体积。方法第一阶段,通过负压吸引辅助脂肪抽吸或超声辅助脂肪抽吸2种方式获取脂肪,并利用2种孔隙尺寸的筛网进行过滤。对移植材料的如下方面进行分析:平均团块大小,油脂、脂肪和水溶性成分的构成比,以及基质血管细胞群(stromalvascularfraction,SVF)的产量。将过滤物及滤液注入无胸腺的裸鼠皮下。第二阶段,将仅通过负压吸引吸脂术中获取脂肪抽吸物,进行离心、纱布摇匀或过滤处理,然后利用相似的规范进行研究。结果与负压吸引脂肪抽吸术相比,超声辅助的脂肪抽吸术获取的脂肪在SVF含量和脂肪移植体内研究成活量情况均相似。通过超声辅助的脂肪抽吸术仅比负压脂肪抽吸术产生稍微多的油脂;通过500μm或800μm孔径的滤网进行过滤均可有效去除液体和油脂。利用纱布法处理的脂肪,其体内移植成活率和SVF产量均最高。对所有移植物的组织学分析均显示为完整的脂肪组织。结论通过超声辅助及负压吸引行脂肪抽吸术获取的脂肪,其在异种移植模型中具有相似的成活率。对于少量填充移植而要求最佳成活率的身体敏感区域而言,利用纱布摇匀的处理方式可能是用于美容性脂肪移植的最佳方法。过滤法和离心法均可有效去除液体成分,其处理过的脂肪具有相似的移植成活率,当所需移植体积较大时,这2种方法均可行。 | Christine Fisher Tara L. Grahovac Mark E. Schafer Ron D. Shippert Kacey G. Marra J. Peter Rubin 魏峰 高景恒 张晨 | 2014 | 中国美容整形外科杂志2014，25，4： | 2 |
| 13 | Guest Editorial for Special Issue on Time Series Classification显示文摘TIME series classification research and applications have recently received a lot of attention.With the rapid advancement of technological devices,time series data are being collected by a wide variety of devices,resulting in a wide range of research and applications.Various fields of studies,ranging from healthcare to weather readings,require time series classification.Activity and action recognition using time series data from fitness trackers are commonly being practiced.Today,a new generation of algorithms and techniques are being used to classify time series data that are extensively available to the research community.For example,recently deep learning techniques that utilize convolutions and recurrent neural networks are being used to classify epileptic seizures from EEG recordings made available at the University of California-Irvine data repository. | Houshang Darabi Georgiana Ifrim Patrick Schafer Diego Furtado Silva | 2019 | IEEE/CAA Journal of Automatica Sinica2019，6，6： | 2 |
| 14 | Review: The Direct Strength Method of cold-formed steel member design显示文摘 | B.W. Schafer | 2008 | Journal of Constructional Steel Research2008，，7： | 2 |
| 15 | Toward a consistent design of structural concrete 显示文摘 | Schlaich J Schafer K Jennewein M | 1987 | Journal of the Prestressed Concrete Institute1987，32，3： | 1 |
| 16 | Polyurethane/polystyrene one- shot interpenetrating polymer networks with good damping ability:Transition broadening through cross-linking, internetwork grafting and compatibilization 显示文摘 | Douglas H J Schafer F U | 1996 | Polymer Advanced Technology1996，7，4： | 1 |
| 17 | PGE1 accelerate thrombolysis by tissue plasminogen activator 显示文摘 | Plavin SR Schafer AI | 1989 | Blood1989，73，： | 1 |
| 18 | Observations on high-anisotropy single crystals using a combined Kerr /magnetic force microscopy显示文摘 | Zueco E Schafer R | 1998 | J Magn Magn Mater1998，，： | 1 |
| 19 | Design and detailing of structural concrete using strut-and-tie models 显示文摘 | Schlaich J Schafer K | 1991 | The Structural Engineer1991，69，6： | 1 |
| 20 | Prognostic factors in adult patients up to 60 years old with acute myeloid leukemia and translocations of chromosome band I lq23: individual patient data-based meta-analysis of the German Acute Myeloid Leukemia Intergroup显示文摘 | Krauter J Wagner K Schafer 1 | 2009 | J Clin Oncol2009，27，18： | 1 |
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