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| 1 | Histological and biochemical alterations in early-stage lobar ischemia-reperfusion in rat liver显示文摘AIM:To investigate the structural and biochemical changes in the early stage of reperfusion in the rat livers exposed to lobar ischemia-reperfusion (IR).METHODS: The median and left lobes of the liver were subjected to 60 min ischemia followed by 5, 10, 30, 45, 60 and 120 min reperfusion. Blood samples were taken at different time intervals to test enzyme activities and biochemical alterations induced by reperfusion. At the end of each reperfusion period, the animals were killed by euthanasia and tissue samples were taken for histological examination and immunohistochemistry. RESULTS: Cell vacuolation, bleb formation and focal hepatitis were the most important changes occur during ischemia. While some changes including bleb formation were removed during reperfusion, other alterations including portal hepatitis, inflammation and the induction of apoptosis were seen during this stage. The occurrence of apoptosis, as demonstrated by apoptotic cells and bodies, was the most important histological change during reperfusion. The severity of apoptosis was dependent on the time of reperfusion, and by increasing the time of reperfusion,the numbers of apoptotic bodies was significantly enhanced. The amounts of lactate dehydrogenase, alanine aminotransferase, aspartate aminotransferase, creatinine and urea were significantly increased in serum obtained from animals exposed to hepatic IR.CONCLUSION: Inflammation and subsequent apoptotic cell death were the most important changes in early-stage hepatic reperfusion injury, and the number of apoptotic bodies increased with time of reperfusion. | Hossein Ali Arab Farhang Sasani Mohammad Hossein Rafiee Ahmad Fatemi Abbas Javaheri | 2009 | World Journal of Gastroenterology2009，15，16： | 16 |
| 2 | Dynamic lumbar pedicle screw-rod stabilization:two-year follow-up and comparison with fusion显示文摘 | Ozer AF Crawford NR Sasani M | 2010 | Open Orthop J2010，4，： | 1 |
| 3 | Dynamic lumbar pedicle screw-rod stabilization:two-year follow-up and comparison with fusion显示文摘 | Ozer AF Crawford NR Sasani M | 2010 | Open Orthop J2010，4，： | 1 |
| 4 | Preserving the ligameneum flavum in lumber discectomy:a new technique that prevents scar tissue formation in the frist 6 months postsurgery显示文摘 | Ozer AF Oktenoglu T Sasani M | 2006 | Neurosurgery2006，59，1： | 1 |
| 5 | Dynamic lumbar pedicle screw-rod stabilization:two-year follow-up and comparison with fusion显示文摘 | OZER A F CRAWFORD N R SASANI M | | 0，，： | 1 |
| 6 | Synthesis and characterization of Anatase and Ruffle TiOz nanorods by template-sssisted method显示文摘 | Sadeghzadeh Attar A Sasani Ghamsari M Hajies- maeilbaigi F | 2008 | J Mater Sci2008，43，： | 1 |
| 7 | Progressive collapse analysis of an RC structure 显示文摘 | Sasani M Kropelnicki J | 2007 | The Structural Design of Tall and Special Buildings2007，17，4： | 1 |
| 8 | Progressive collapse resistance of hotel San Diego 显示文摘 | Sasani M Sagiroglu S | 2008 | Journal of Structural Engineering2008，134，3： | 1 |
| 9 | Response of a Reinforced Concrete In- filled-frame Structure to Removal of Two Adjacent Columns 显示文摘 | SASANI M | 2008 | Engineering Structures2008，30，9： | 1 |
| 10 | Single-stage posterior corpectomy and expandable cage placement for treatment of thoracic or lumbar burst fractures显示文摘 | Sasani M Ozer AF | 2009 | Spine2009，3，4： | 1 |
| 11 | Synthesis of TiO2 nanoparticles by hydrolysis and peptization of titanium isopropoxide solution显示文摘 | MAHSHID S ASKARI M SASANI GHAMSARI M | 2007 | Journal of Materials Processing Technology2007，189，23： | 1 |
| 12 | Total disc replacement inthe treatment of lumbar discogenic pain with discherniation:a pro-spective clinical study显示文摘 | Sasani M Oktenoglu T Tuncay K | 2009 | Turk Neurosurg2009，19，2： | 1 |
| 13 | A short history ofposterior dynamic stabilization 显示文摘 | Gomleksiz C Sasani M Oktenoglu T | 2012 | Adv Orthop2012，2012，62： | 1 |
| 14 | Damping in shear beam structures and estimation of drift response 显示文摘 | Sasani M Makris N Bolt B A | 2006 | Journal of Engineering Mechanics2006，132，8： | 1 |
| 15 | Preparation and characterization of ZnO nanoparticles by a novel sol gel route显示文摘 | VAFAEE M SASANI GHAMSARI M | 2007 | Materials Letters2007，61，： | 1 |
| 16 | Progressive Collapse Resistance of Hotel San Diego显示文摘 | Mehrdad Sasani | 2008 | Journal of Structural Engineering2008，134，3： | 1 |
| 17 | Seismic fragility of RC structural walls: displacement approach 显示文摘 | Sasani M Kiureghian A D | 2001 | Journal of Structural Engineering2001，127，2： | 1 |
| 18 | Preparation and characterization of ZnO nanoparticles by a novel sol - gel route显示文摘 | VAFAEE M SASANI G M | 2006 | Materials Letters2006，61，1415： | 1 |
| 19 | Percutaneous endoscopic discec- tomy for far lateral lumbar disc heriations: prospective study and outcome of 66 patients显示文摘 | Sasani M Ozer AF Oktenoglu T | 2007 | Minim Invas Neurosurg2007，50，： | 1 |
| 20 | Minimum two-year follow-up of cases with recurrent disc herniation treated with microdiscectomy and posterior dynamic transpedicular stabilisation 显示文摘 | Kaner T Sasani M Oktenoglu T | 2010 | Open Orthop J2010，4，： | 1 |
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