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| 1 | Isolation of the mucilages from Hibiscus rosasinensis linn.and Okra(Abelmoschus esculentus linn.) and studies of the binding effects of the mucilages显示文摘Objective:To isolate and evaluate comparatively the binding efficacy of the mucilages obtained from the plants of Hibiscus rosasinensis and Okra(Abelmoschus esculentus).Methods:Extraction of mucilages from the leaves of Hibiscus and pods of Okra(Ladies finger) was carried out by a cold maceration process.The extracted mucilages were subjected to various physicochemical properties for its suitability as an excipient in the formulation of tablet dosage form.Different concentrations(10,8,5,2 and 1%w/v) of binder solutions of Hibiscus and Okra were used for the formulation of tablets and the formulated tablets were evaluated by studying the standard parameters like diameter,thickness,weight variation,hardness,friability,disintegration and in vitro dissolution.Stability studies of the formulated tablets were conducted for four weeks. Results:The formulated tablets prepared using the mucilages of both Hibiscus and Okra had good appearance.The in vitro drug release profile of the tablets prepared using Okra mucilage had an optimum of 90%at a mucilage concentration of 1%w/v concentration mucilage itself within 4 h.Conclusions:According to the observations,the lower concentration levels of Okra can be used as an alternative binder to starch.The higher concentration levels of Okra mucilage show a slow and sustained release,and can be considered as an alternative natural excipient in the modified drug delivery systems.At the same time,the above natural excipient of Hibiscus mucilage could be used as a platform for prolonged release if its binder concentrations are increased. | Ameena K Dilip C Saraswathi R Krishnan PN Sankar C Simi SP | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，7： | 8 |
| 2 | Antimicrobial activity of cotton and silk fabric with herbal extract by micro encapsulation显示文摘Objective:To explore the antimicrobial activity of microcapsules encapsulated with mixture of herbs like neem,tulsi and turmeric,and its application on cellulosic fabric in the form of microcapsules.Methods:The microcapsules were prepared from the mixture of herbs by plain diffusion method,a natural encapsulation technique with yeast and applied on cotton and silk fabric by pad-dry-cure method.The microcapsules were fixed on cotton and silk fabric using the binder UF Silpure FBR-5(PA)B at 120℃.The antimicrobial activities of the finished fabric were assessed by using three types of bacteria including Staphylococcus aureus,Escherichia coli and Pseudomonas.Results:The results of antimicrobial activity from the tests including parallel streak method and disc diffusion method showed that activity of the mixture of herbs was very effective among the three types of bacteria selected,and the antimicrobial activity of prepared microcapsule against Pseudomonas was very good.Conclusions:The herbal microcapsule treated fabric could be applied in the field of medicine.The scanning electron microscope photographs ensure the fixing of the microcapsules firmly in the yarn structure of plain woven cotton and silk fabric. | Saraswathi R Krishnan PN Dilip C | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，2： | 3 |
| 3 | A Suevey on Con- tent based Medical Image Retrieval for Mri Brain Images 显示文摘 | Sharmila G Saraswathi D Ramkumar R | 2014 | International Journal of Research in Engineering and Technology2014，3，19： | 1 |
| 4 | Chemo-and regioselective conversion of epoxides to carbonyl compounds in 5 M lithium perchlorate-diethyl ether medium 显示文摘 | R Sudha K Malola Narasimhan Geetha Saraswathy | 1996 | J Org Chem1996，61，： | 1 |
| 5 | Formulation and evaluation of herbal gel of Pothos scandens Linn显示文摘Objective:To formulate Pothos scandens Linn(P.scandens) leaf extract in to a gel and investigate their burn wound healing activity.Methods:Ethanolic extract of dried leaves of P. scandens were subjected to priliminery phytochemical evaluation and wound healing activities studies.Different gel formulations of ethanolic extract of P.scandens(4%w/v) were prepared using polymers carbopol 934 and carbopol 940 bv varying their concentration.These formulations were evaluated for physical parameters,drug content.pH,viscosity,extrudability.spreadability. primary skin irritation,pharmacological activity and stability.Results:Wound healing studies of ethanolic extract revealed that P.scandens treated animals were found to epithelise in 22 days while the solvent control and the untreated rats epithelise within 35 and 40 days respectively. The formulation with 1.5%w/w carbopol 934 was found to be more promising as it shows better physicochemical characteristics,higher pharmacological activity and stability compared to other formulations.Conclusions:P.scandens alcoholic extract shows significant improvement in burn wound contraction and hence this is a promising candidate in burn wound healing. | Mohammed Haneefa KP Shahima Hanan K Saraswathi R Guru Prasad Mohanta Chandini Nayar | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，12： | 1 |
| 6 | Studies on the aspects of chloride ion determination in different types of concrete under macro-cell corrosion conditions显示文摘 | MURALIDHARAN S VEDALAKSHMI R SARASWATHI V | 2005 | Building and Environment2005，40，9： | 1 |
| 7 | Genotoxic assessment in peripheral blood lymphocytes of post- polio individuals using sister chromatid exchange analysis and micronucleus assay 显示文摘 | BHATFACHARYA S K SARASWATHY R SIVAKUMAR E | 2011 | Hum Exp Toxicol2011，30，7： | 1 |
| 8 | MTHFR C667T and factor V Leiden in recurrent pregnancy loss: a study among an endogamous group in Nor'th India显示文摘 | Mukhopadhyay R Saraswathy KN Ghost PK | 2009 | Genet Test Mol Biomarkers2009，13，： | 1 |
| 9 | Evaluation of a composite corrosion-inhibiting admixture and its performance in concrete under macrocell corrosion conditions 显示文摘 | SARASWATHY V MURALIDHARAN S KALYANASUNDARAM R M | 2001 | Cement and Concrete Research2001，，31： | 1 |
| 10 | Determination of diffusion coefficient of chloride in concrete using Warburg diffusion coefficient显示文摘 | VEDALAKSHMI R SARASWATHY V SONG H W | 2009 | Corros Sci2009，51，6： | 1 |
| 11 | Mycelial pelle! for- mation by penicillium ochrochloron species due to expo-sure to pyrene 显示文摘 | SARASWATHY A HALLBERG R | 2005 | Microbiological Research2005，160，4： | 1 |
| 12 | Evaluation of a composite corrosion-inhibiting admixture and its performance in concrete under macrocell corrosion conditions显示文摘 | Saraswathy V Muralidharan S Kalyanasundaram R M | 2001 | Cement and Concrete Research2001，31，： | 1 |
| 13 | Investigation ofoxygen reduction at platinum loaded poly ( o-phenylen-ediamine) electrode in acid medium 显示文摘 | Gajendran P Vijayanand S Saraswathi R | 2007 | J ElectroanalCAem2007，601，： | 1 |
| 14 | Chemoand Regioselective Conversion of Epoxides to Carbonyl Compounds in 5 M Lithium Perchlorate-Diethyl Ether Medium显示文摘 | Sudha R Malola K Narasimhan Geetha Saraswathy V | 1996 | J Org Chem1996，61，： | 1 |
| 15 | Stud- ies on the aspects of chloride ion determination in different types of concrete under macro-cell corrosion conditions 显示文摘 | Muralidharan S Vedalakshmi R Saraswathi V | 2005 | Building and Environment2005，40，9： | 1 |
| 16 | Inhibition of CC14-induced liver fibrosis by Piper longum Linn 显示文摘 | CHRISTINA A J M SARASWATHY G R HEISON ROBERT S J | 2006 | Phytomedicine2006，13，3： | 1 |
| 17 | Redox properties of poly(N- methylaniline)显示文摘 | SIVAKUMAR R SARASWATHI R | 2003 | Synthetic Metals2003，，138： | 1 |
| 18 | Investigation of oxygen reduction at platinum loaded poly ( o - phenylenediamine) electrode in acid medium 显示文摘 | Gajendran P Vijayanand S Saraswathi R | 2007 | Journal of Electroanalytical Chemistry2007，601，12： | 1 |
| 19 | Electrodeposition within zeolite membrane hosts 显示文摘 | SENTHILKUMAR S ADISA A SARASWATHI R | 2008 | Electrochemistry Communications2008，10，： | 1 |
| 20 | Characterization of poly (N-methylaniline) as a cathode active material in acqueous rechargeable batteries显示文摘 | Sivakkumar R Saraswathi R | 2002 | J Power Sources2002，104，： | 1 |
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