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| 1 | Fatty liver in hepatitis C patients post-sustained virological response with direct-acting antivirals显示文摘AIM To determine steatosis and fibrosis prevalence in hepatitis C patients after a sustained virological response achieved with direct-acting antivirals.METHODS Transient elastography with controlled attenuation parameter(CAP) was used to assess hepatic steatosis post-sustained virological response(SVR);the CAP technology was not available in the United States at study initiation.Liver stiffness/fibrosis was measured before and 47 wk after treatment completion.Patients with genotype 3 and patients with cirrhosis were excluded.RESULTS One hundred and one patients were included in the study.Post-SVR there were decreases from baseline in alanine aminotransferase(ALT)(63.1 to 17.8 U/L),aspartate aminotransferase(51.8 to 21.5 U/L) and fibrosis score(7.4 to 6.1 k Pa)(P < 0.05).Post-SVR,48 patients(47.5%) had steatosis on CAP;of these,6.25% had advanced fibrosis.Patients with steatosis had higher body mass index(29.0 vs 26.1 kg/m2),glucose(107.8 vs 96.6 mg/d L),ALT(20.4 vs 15.3 mg/d L),CAP score(296.3 vs 212.4 d B/m) and fibrosis score(7.0 vs 5.3 k Pa);P < 0.05.Interestingly,compared to baseline,both patients with and without steatosis had change in fibrosis score post-SVR(7.7 k Pa vs 7.0 k Pa and 7.0 k Pa vs 5.3 k Pa);alternatively,(P < 0.05) and therefore patients with steatosis continued to have clinically significant stiffness(≥ 7 k Pa).CONCLUSION Fatty liver is very common in hepatitis C virus(HCV) patients post-SVR.These patients continue to have elevated mean fibrosis score(≥ 7 k Pa) compared to those without fatty liver;some have advanced fibrosis.Long term follow up is needed to assess steatosis and fibrosis in HCV patients post-SVR. | Mazen Noureddin Micaela M Wong Tsuyoshi Todo Shelly C Lu Arun J Sanyal Edward A Mena | 2018 | World Journal of Gastroenterology2018，24，11： | 6 |
| 2 | A Novel Defected Ground Structure for Planar Circuits 显示文摘 | Mandal M K Sanyal S | 2006 | IEEE Microwave and Wireless Components Letters2006，16，2： | 1 |
| 3 | Liquid chromato- graphy tandem mass spectrometry assay for the simultaneous determination of venlafaxine and O- desmethylvenlafaxine in human plasma and its application to a bioequivalence study显示文摘 | PATEL BN SHARMA N SANYAL M et ol | 2008 | J Pharm Biomed Anal2008，47，3： | 1 |
| 4 | Varied presentations of Sheehan's syndrome at diagnosis: A review of 18 patients 显示文摘 | Sanyal D Raychaudhuri M | 2012 | Indian J Endocr Metab2012，16，2： | 1 |
| 5 | A high throughput and selective method for the estimation of valproic acid an antiepileptic drug in human plasma by tandem LC-MS/MS显示文摘 | Jain DS Subbaiah G Sanyal M | 2007 | Talanta2007，72，1： | 1 |
| 6 | Rules ofengagement:factors that regulate activity-dependent synapticplasticity during neural network development显示文摘 | Stoneham E T Sanders E M Sanyal M Dumas T C | 2010 | Biol Bull2010，219，： | 1 |
| 7 | LC-MS-ESI for the determination of loratadine and descarboethoxyloratadine in hu- man plasma显示文摘 | PATEL BN SHARMA N SANYAL M | 2010 | J Chromatogr Sci2010，48，1： | 1 |
| 8 | Managing Total Circulation Losses With Crossflow While Drilling: Case History of Practical Solution显示文摘 | Suyan K M Dasgupta D Sanyal D | | SPE0，，： | 1 |
| 9 | Three-dimensional simulation of bubble column flows with bubble coalescence and breakup显示文摘 | Chen P Dudukovic M P Sanyal J | 2005 | AIChE J2005，51，3： | 1 |
| 10 | The one-step Pickering emulsion polymerization route for synthesizing organic-inorganic nanoeomposite particles显示文摘 | Ma H Luo M X Sanyal S | 2010 | Materials2010，3，2： | 1 |
| 11 | Adsorption/desorption of mono - and diblock copolymers on surfaces using specific hydrogen bonding interaetions 显示文摘 | Sanyal A Norsten T B Uzun O Rotello V M | 2004 | Langmuir2004，20，： | 1 |
| 12 | Study of thin film multilayers using X-ray refleetivity and scanning probe microscopy 显示文摘 | BANERJEE S DATrA A SANYAL M K | 2001 | Vacuum2001，60，4： | 1 |
| 13 | High throughput and sensitive determination of trazodone and its primary metabolite,m-chlorophenylpiperazine,in human plasma by liquid chromatography-tandem mass spectrometry显示文摘 | PATEL B N SHARMA N SANYAL M | 2008 | Journal of Chromatography B2008，871，1： | 1 |
| 14 | Three dimensional simulation of bubble column flows with bubble coales- cence and breakup显示文摘 | Chen P Dudukovic M P Sanyal J | 2005 | AIChE J2005，51，3： | 1 |
| 15 | Low insertion loss, wideband bandpass filters with sharp rejection characteristics显示文摘 | Mandal M K Mondal P Sanyal S | 2010 | IET Microwaves Antennas & Propagation2010，4，1： | 1 |
| 16 | Seawater pH control on the boron isotopic composition of calcite: evidence from inorganic calcite precipitation experiments显示文摘 | Sanyal A Nugent M Reeder R J | 2000 | Geochimica et Cosmochimica Acta2000，64，9： | 1 |
| 17 | Three-dimensional simulation of bubble column flows with bubble coalescence and breakup显示文摘 | CHEN P DUDUKOVIC M P SANYAL J | 2005 | AIChE J2005，51，3： | 1 |
| 18 | Localization of nitric oxide synthase in human trophoblast cells: role of nitric oxide in trophoblast proliferation and differentiation 显示文摘 | SANYAL M NAY T C DAS C | 2000 | Am J Reprod Immunol2000，43，2： | 1 |
| 19 | Hepatic Lidocaine Metabolism and Liver Histology in Patients with Chronic Hepatitis and Cirrhosis显示文摘 | SHIFFMAN M L LUKETIC V A SANYAL A J | 1994 | Hepatology1994，19，6： | 1 |
| 20 | Study of thin film multilayers using X-ray reflectivity and scanning probe microscopy显示文摘 | BANERJEE S DATTA A SANYAL M K | 2001 | Vacuum2001，60，4： | 1 |
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