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| 1 | Single center experience of capsule endoscopy in patients with obscure gastrointestinal bleeding显示文摘AIM:To identify optimum timing to maximize diagnostic yield by capsule endoscopy (CE) in patients with obscure gastrointestinal bleeding (OGIB).METHODS:We identified patients who underwent CE at our institution from August 2003 to December 2009.Patient medical records were reviewed to determine type of OGIB (occult,overt),CE results and complications,and timing of CE with respect to onset of bleeding.RESULTS:Out of 385 patients investigated for OGIB,284 (74%) had some lesion detected by CE.In 222 patients (58%),definite lesions were detected that could unequivocally explain OGIB.Small bowel ulcer/erosions secondary to Crohn's disease,tuberculosis or non-steroidal anti-inflammatory agent use were the commonest lesions detected.Patients with overt GI bleeding for < 48 h before CE had the highest diagnostic yield (87%).This was significantly greater (P < 0.05) compared to that in patients with overt bleeding prior to 48 h (68%),as well as those with occult OGIB (59%).CONCLUSION:We established the importance of early CE in management of OGIB.CE within 48 h of overt bleeding has the greatest potential for lesion detection. | Mahesh Kumar Goenka Shounak Majumder Sanjeev Kumar Pradeepta Kumar Sethy Usha Goenka | 2011 | World Journal of Gastroenterology2011,17,6: | 39 |
| 2 | Non-invasive means of measuring hepatic fat content显示文摘Hepatic steatosis affects 20% to 30% of the general adult population in the western world. Currently, the technique of choice for determining hepatic fat deposition and the stage of fibrosis is liver biopsy. However, it is an invasive procedure and its use is limited, particularly in children. It may also be subject to sampling error. Non-invasive techniques such as ultrasound, computerised tomography (CT), magnetic resonance imaging (MRI) and proton magnetic resonance spectroscopy (1H MRS) can detect hepatic steatosis, but currently cannot distinguish between simple steatosis and steatohepatitis, or stage the degree of fibrosis accurately. Ultrasound is widely used to detect hepatic steatosis, but its sensitivity is reduced in the morbidly obese and also in those with small amounts of fatty infiltration. It has been used to grade hepatic fat content, but this is subjective. CT can detect hepatic steatosis, but exposes subjects to ionising radiation, thus limiting its use in longitudinal studies and in children. Recently, magnetic resonance (MR) techniques using chemical shift imaging have provided a quantitative assessment of the degree of hepatic fatty infiltration, which correlates well with liver biopsy results in the same patients. Similarly, in vivo 1H MRS is a fast, safe, non-invasive method forthe quantification of intrahepatocellular lipid (IHCL) levels. Both techniques will be useful tools in future longitudinal clinical studies, either in examining the natural history of conditions causing hepatic steatosis (e.g. non-alcoholic fatty liver disease), or in testing new treatments for these conditions. | Sanjeev R Mehta E Louise Thomas Jimmy D Bell Desmond G Johnston Simon D Taylor-Robinson | 2008 | World Journal of Gastroenterology2008,14,22: | 21 |
| 3 | 下肢动脉64层CT血管成像两种成像方法图像质量的比较显示文摘目的探讨小剂量团注试验技术多层螺旋CTA(MSCTA)在周围动脉闭塞性疾病(PAOD)的应用价值。方法回顾性分析44例PAOD患者,其中,触发组18例,采用自动触发扫描技术,用64层CT行CTA;试验组26例,采用2次小剂量(对比剂各15ml)团注试验法行CTA,根据T12椎体动态扫描达峰时间(TAO)及膝关节水平的动态扫描达峰时间(TPOP)确定CTA的扫描延时点及扫描持续时间。每组CTA图像由2名有经验的高年资主治医师对下列5个方面独立进行评价:(1)显示血管的最远分支级别;(2)动脉边缘光滑度;(3)静脉干扰情况;(4)动脉狭窄级别;(5)4个动脉节段的CT值,比较2组患者的CTA图像质量。对2名评价者的评分计算Kappa值。对2组患者的动脉分支级别、血管边缘、静脉干扰评分和测量的CT值应用t检验,对2组患者动脉狭窄分级的构成比应用单项有序资料χ^2检验。结果试验组2次小剂量团注试验显示,对比剂到达腹主动脉的峰值时间(TAO)为12.0~22.0s,平均(17.1±2.6)s;腹主动脉.胭动脉的通过时间(T1)为8.0—24.0s,平均(14.8±5.5)s,个体差异较大。试验组患者膪动脉以下及足部动脉CTA的图像质量较触发组高(P〈0.05)。对于试验组的CTA图像,2名医师评价结果显示了很好的一致性(K值均〉0.80);在触发组胭动脉以下的CTA图像,静脉干扰及狭窄级别评价的一致性较差(K分别为0.60及0.50)。胭动脉以下及足动脉狭窄级别评分,触发组病例明显高于试验组(〈值分别为30.55及22.41,P〈0.01)。结论2次小剂量团注试验法MSCTA考虑到了PAOD患者腹主动脉到胭动脉通过时间的个体差异,在膝关节以下动脉图像质量较团注触发法MSCTA高。 | 崔磊 胡春洪 Sanjeev PS 方向明 胡晓云 张庆华 王艾丽 | 2009 | 中华放射学杂志2009,43,3: | 19 |
| 4 | 不同入路冠状动脉介入治疗术围手术期周围血管并发症发生率的对比显示文摘目的:比较经股动脉和桡动脉入路冠状动脉介入治疗(percutaneous coronary intervention,PCI)术中周围血管并发症的发生率,为其临床诊治提供参考。方法:分析2014年7月至2016年12月在我院心血管介入治疗中心进行冠状动脉造影及介入治疗的780例患者的临床资料,比较周围血管并发症发生情况。结果:经股动脉途径471例,经桡动脉途径309例。经股动脉途径总体并发症发生率13.2%,高于经桡动脉途径的4.5%,差异有统计学意义(P<0.001)。经股动脉途径出血并发症发生率为7.9%,高于经桡动脉途径2.6%,差异有统计学意义(P=0.002)。经股动脉途径患者重大并发症(后腹膜血肿、假性动脉瘤、动静脉瘘、动脉夹层形成)发生率高于经桡动脉途径(2.1%vs 0%),但差异无统计学意义。结论:经股动脉途径冠状动脉介入治疗术围手术期周围血管并发症发生率高于经桡动脉途径,临床入路选择时需综合考虑。 | 张树清 崔磊 祁荣兴 SANJEEV KUMAR P S 黄胜 葛莉 钱澄 | 2017 | 中国临床医学2017,24,5: | 11 |
| 5 | Novel anticancer agents from plant sources显示文摘植物仍然是新药,新药领先和新化学实体的重要来源。植物基于的药发现主要导致了 anticancer 和反传染的代理人的发展,并且继续在临床的试用贡献新领先。自然产品药在药品的照顾起一个主导的作用。几导出植物的混合物成功地当前在癌症治疗被采用。有为药的进一步的改进和开发学习的导出植物的细胞毒素的自然产品的许多类。从关于植物 antitumor 代理人的研究导出的新 anticancer 药将连续地被发现。这评论的基本目的是从药用的植物探索最新发现的 anticancer 混合物的潜力,作为为 anticancer 药开发的领先。在地球附近为研究人员和科学家从他们探索植物并且为新药发现的药用的价值将是有用的。 | Shah Unnati Shah Ripal Acharya Sanjeev Acharya Niyati | 2013 | 中国天然药物2013,11,1: | 9 |
| 6 | Risk of New-Onset Atrial Fibrillation in Elderly Patients with the Overlap Syndrome: A Retrospective Cohort Study显示文摘Background Co-existence of obstructive sleep apnea (OSA) and chronic obstructive pulmonary disease (COPD) is referred to as overlap syndrome. Overlap patients have greater degree of hypoxia and pulmonary hypertension than patients with OSA or COPD alone. Studies showed that elderly patients with OSA alone do not have increased risk of atrial fibrillation (AF) but it is not known if overlap patients have higher risk of AF. Objective To determine whether elderly patients with overlap syndrome have an increased risk of AF. Methods In this single center, community-based retrospective cohort analysis, data were collected on 2,873 patients > 65 years of age without AF, presenting in the year 2006. Patients were divided into OSA group (n = 60), COPD group (n = 416), overlap syndrome group (n = 28) and group with no OSA or COPD(n = 2369). The primary endpoint was incidence of new-onset AF over the following two years. Logistic regression was performed to adjust for heart failure (HF), coronary artery disease, hypertension (HTN), cerebrovascular disease, cardiac valve disorders, diabetes mellitus, hyperlipidemia, chronic kidney disease (CKD) and obesity. Results The incidence of AF was 10% in COPD group, 6% in OSA group and 21% in overlap syndrome group (P < 0.05). After adjusting for age, sex, HF, CKD, and HTN, patientswith overlap syndrome demonstrated a significant association with new-onset AF (OR = 3.66, P = 0.007). HF, CKD and HTNwere also significantly associated with new-onset AF (P < 0.05). Conclusion Among elderly patients, the presence of overlap syndrome is associatedwith a marked increase in risk of new-onset AF as compared to the presence of OSA or COPDalone. | Harsha V. Ganga Sanjeev U. Nair Venkata K. Puppala Wayne L. Miller | 2013 | Journal of Geriatric Cardiology2013,10,2: | 9 |
| 7 | Characterization of hepatic progenitors from human fetal liver using CD34 as a hepatic progenitor marker显示文摘AIM: To enrich putative hepatic progenitors from the developing human fetal liver using CD34 as a marker. METHODS: Aborted fetuses of 13-20 wk were used for the isolation of liver cells. The cells were labeled with anti CD34; a marker used for isolating progenitor population and the cells were sorted using magnetic cell sorting. The positive fractions of cells were assessed for specific hepatic markers. Further, these cells were cultured in vitro for long term investigation. RESULTS: Flow cytometric and immunocytochemical analysis for alphafetoprotein (AFP) showed that the majority of the enriched CD34 positive cells were positive for AFP. Furthermore, these enriched cells proliferated in the long term and maintained hepatic characteristics in in vitro culture. CONCLUSION: The study shows that aborted human fetal liver is a potential source for isolation of hepatic progenitors for clinical applications. The study also demonstrates that CD34 can be a good marker for the enrichment of progenitor populations. | Parveen Nyamath Ayesha Alvi Aejaz Habeeb Sanjeev Khosla Aleem A Khan CM Habibullah | 2007 | World Journal of Gastroenterology2007,13,16: | 9 |
| 8 | Pediatric hepatocellular carcinoma显示文摘Pediatric hepatocellular carcinoma (HCC) is the second common malignant liver tumor in children after hepato-blastoma. It differs from the adult HCC in the etiological predisposition, biological behavior and lower frequency of cirrhosis. Perinatally acquired hepatitis-B virus, hepa-torenal tyrosinemia, progressive familial intrahepatic cho-lestasis, glycogen storage disease, Alagille's syndrome and congenital portosystemic shunts are important predis-posing factors. Majority of children (87%) are older than 5 years of age. Following mass immunization against hepatitis-B, there has been a drastic fall in the incidence of new cases of pediatric HCC in the Asia-Pacific region. Management is targeted on complete surgical removal either by resection or liver transplantation. There is a trend towards improving survival of children transplanted for HCC beyond Milan criteria. Chemotherapeutic regi-mens do not offer good results but may be helpful for down-staging of advanced HCC. Surveillance of children with chronic liver diseases with ultrasound and alpha-fetoprotein may be helpful in timely detection, intervention and overall improvement in outcome of HCC. | Rajeev Khanna Sanjeev Kumar Verma | 2018 | World Journal of Gastroenterology2018,24,35: | 9 |
| 9 | Synergistic effects of biochar/microbial inoculation on the enhancement of pig manure composting显示文摘With the aim to comparatively investigate the effect of the addition of additives such as biochar(BC),microbial inoculation(MI)and biochar/microbial inoculation(BCMI)on composting enhancement,nitrogen conservation,greenhouse gas emissions,the quality improvement of pig manure compost were comparatively investigated in a 42-day aerobic pig manure composting experiment.The results showed that the duration of the thermophilic stage,the degradation of organic matter and the detoxification of the compost were enhanced in the BC,MI and BCMI treatments compared with those in the control(without additive).Moreover,the content of total Kjeldahl nitrogen in the BC,MI and BCMI treatments was increased by 38.1,48.9 and 59.0%,respectively,through the reduction of NH_(3) volatilization and N_(2)O production,which were higher than those of the control(31.8%).A reduction in CH_(4) release during composting was not observed with the MI and BCMI treatments.Following 42 days of composting,the final product of the three treatments exhibited acceptable potential for use as a fertilizer in agriculture;the BCMI treatment showed an especially synergistic effect on pig manure composting enhancement. | Zhineng Tu Xiuna Ren Junchao Zhao Sanjeev Kumar Awasthi Quan Wang Mukesh Kumar Awasthi Zengqiang Zhang Ronghua Li | 2019 | Biochar2019,1,1: | 8 |
| 10 | Anti-HBc screening in Indian blood donors:Still an unresolved issue显示文摘AIM:To study the seroprevalence of antibody to hepatitis B core antigen (anti-HBc) in healthy blood donors negative for HBsAg and to evaluate whether anti-HBc detection could be adopted in India as a screening assay for HBV in addition to HBsAg. METHODS: A total of 1700 serum samples collected from HBsAg-negative healthy blood donors were tested for the presence of anti-HBc antibody (IgM + IgG). All samples reactive for anti-HBc antibody were then investigated for presence of anti-HBs and for liver function tests (LFTs). One hundred serum samples reactive for anti-HBc were tested for HBV DNA by PCR method. RESULTS: Out of 1700 samples tested, 142 (8.4%) blood samples were found to be reactive for anti-HBc. It was signif icantly lower in voluntary (6.9%) as compared to replacement donors (10.4%, P = 0.011). Seventy- two (50.7%) anti-HBc reactive samples were also reactive for anti-HBs with levels > 10 mIU/mL and 70 (49.3%) samples were non-reactive for anti-HBs, these units were labeled as anti-HBc-only. These 142 anti-HBc reactive units were also tested for liver function test. HBV DNA was detected in only 1 of 100 samples tested. CONCLUSION: Keeping in view that 8%-18% of donor population in India is anti-HBc reactive, inclusion of anti- HBc testing will lead to high discard rate. Anti-HBs as proposed previously does not seem to predict clearance of the virus. Cost effectiveness of introducing universalanti-HBc screening and discarding large number of blood units versus considering ID NAT (Individual donor nuclic acid testing) needs to be assessed. | Hari Krishan Dhawan Neelam Marwaha Ratti Ram Sharma Yogesh Chawla Beenu Thakral Karan Saluja Sanjeev Kumar Sharma Manish K Thakur Ashish Jain | 2008 | World Journal of Gastroenterology2008,14,34: | 8 |
| 11 | Dynamic response of concrete pavement structure with asphalt isolating layer under moving loads显示文摘A three-dimensional finite element model(3D FEM) is built using ABAQUS to analyze the dynamic response of a concrete pavement structure with an asphalt isolating layer under moving loads.The 3D model is prepared and validated in the state of no asphalt isolating layer.Stress and deflection at the critical load position are calculated by changing thickness,modulus of isolating layer and the combination between the isolating layer and concrete slab.Analysis result shows that the stress and deflection of the concrete slab increase with the increase of thickness.The stress and deflection of the concrete slab decrease with the increase of combination between the isolating layer and concrete slab.The influence of changing the isolating layer modulus to the stress and deflection of the concrete slab is not significant.From the results,asphalt isolating layer design is suggested in concrete pavement. | Jianmin Wu Jiaping Liang Sanjeev Adhikari | 2014 | Journal of Traffic and Transportation Engineering(English Edition)2014,1,6: | 7 |
| 12 | 能谱CT在鉴别直径≤2 cm肺炎性结节与肺癌中的价值显示文摘目的 探讨能谱CT在鉴别直径≤2 cm的肺炎性结节和肺癌中的作用。方法 回顾性分析43例经病理证实的直径≤2 cm的孤立性肺结节(SPN)患者的资料,其中炎性结节13例,肺癌30例,均已行宝石能谱成像(GSI)扫描。测量2组结节动静脉期碘浓度(IC)、40 keV和90 keV对应的CT值,计算动静脉期标准化碘浓度(NIC),动静脉期标准化碘浓度差值(ICD),动静脉期能谱曲线斜率(40~90 keV)。对2组结节的上述指标进行独立样本t检验及受试者工作特征曲线(ROC曲线)分析。结果 炎性SPN动脉期NIC(0.12±0.02)<肺癌(0.17±0.03)(P<0.01),炎性SPN静脉期NIC(0.46±0.02)>肺癌(0.37±0.09)(P〈0.01)。炎性SPN ICD(0.34±0.03)>肺癌 (0.19±0.08)(P<0.01),NIC和ICD均有统计学意义(P<0.01)。两者动静脉期能谱曲线斜率(λHU)均无统计学意义(P>0.05)。鉴别两者的最佳定量参数值是ICD,其阈值0.29鉴别两者的敏感性和特异性分别为84.0%、100%。其次为动脉期NIC,其阈值0.15鉴别两者的敏感性和特异性分别为72.0%、100%。结论 能谱CT IC多参数分析对鉴别直径≤2 cm炎性SPN与肺癌的诊断价值较大,ICD和动脉期NIC具有较高的敏感度与特异度。 | 朱慧 郁义星 Sanjeev kumar PS 包捷 王希明 胡春洪 | 2018 | 实用放射学杂志2018,34,11: | 7 |
| 13 | Salt Tolerance Mechanisms and Approaches:Future Scope of Halotolerant Genes and Rice Landraces显示文摘All rice plant developmental stages are severely affected by soil salinity. Salinity-induced ionic and osmotic stresses affect stomata closure and gaseous exchange, and reduce transpiration and the rate of carbon assimilation, and hence decrease plant yield. Understanding the response of rice plants toward salinity stress at the genetic level and developing salt-tolerant varieties are the vital mandates for its effective management. This review described the present status of salt-tolerance achieved in rice by various mechanisms including the ion homeostasis(Na^+/H^+, OsNHX antiporters), compatible organic solutes(glycine betaine and proline), antioxidative genes(OsECS, OsVTE1, OsAPX and OsMSRA4.1), salt responsive regulatory elements(transcription factors, cis-acting elements and miRNAs) and genes ecoding protein kinases(MAPKs, SAPKs and STRKs). Further, the future perspective of developing salt-tolerant varieties lies in exploring halotolerant gene homologs from rice varieties, especially the landraces. Genetic diversity among rice landraces can serve as a valuable resource for future studies toward variety improvement through breeding and genome editing. Further, identification, multiplication, preservation and utilization of biodiversity among landraces are the urgent buffers to be saved as a heritage for future generations to come. | Tarun Bhatt Aditi Sharma Sanjeev Puri Anu Priya Minhas | 2020 | Rice science2020,27,5: | 6 |
| 14 | Differential Sensitivity of Macrocarpa and Microcarpa Types of Chickpea (Cicer arietinum L.) to Water Stress: Association of Contrasting Stress Response with Oxidative Injury显示文摘Chickpea (Cicer arietinum L.) 是特别地敏感的在它的繁殖阶段浇应力并且在水应力的条件下面,将放弃花和豆荚,因此减少收益潜力。有 chickpea 的二种类型:(i) Macrocarpa (Kabuli ) 它有大,击打塑造头的、轻棕色的种子;并且(ii ) Microcarpa (Desi ) 它有小、尖、黑暗褐的种子。相对说, Kabuli 被报导了更敏感比 Desi 浇应力。与对比敏感流水联系的内在的机制在新陈代谢的水平强调井没被理解。我们假设了一个原因因为在 chickpea 的二种类型的形成对照的水压力敏感可以是在氧化损害的一个变化。在现在的学习,两种类型的植物是为 14 d 在繁殖舞台强调的水。由于压力, Kabuli 类型与为 Desi 类型观察的 64% 减小相比在控制上在种子产量展出了 80% 减小。在叶水潜力(w) 的减少与 Desi 类型相比在 Kabuli 是更快的。在水压力时期的结束, w 被归结为 ? 2.9 并且 ? 分别地,没有他们之间的任何重要差别,在 Desi 和 Kabuli 的 3.1 MPa 打字。在应力的最后一天, Kabuli 比 Desi 经历了 20% 更多的膜损害。叶绿素内容和光合的率与 Kabuli 相比在 Desi 是显著地更大的。malondialdehyde 和 H2O2 内容与 Desi 相比在在 Kabuli 的水压力的结束是显著地更高的,显示在前者的更大的氧化应力。抗氧化剂的层次例如维生素酸和谷胱甘肽,比 Kabuli 在 Desi 是显著地更高的。, Superoxide dismutase 和过氧化氢酶活动没在第 10 天, ascorbate peroxidase 的活动, dehydroascorbate reductase,和谷胱甘肽 reductase 在 chickpea 的二种类型之间显著地不同在 Desi 是更高的。这些调查结果显示在 Desi 类型的更大的应力公差可以被归功于到它维持更好的水地位的优异能力,它导致更少的氧化损坏。另外,实验室研究由使 chickpea 的两种类型遭到到聚乙烯的类似的层次进行了导致乙二醇的水应力并且到 10 .mol/L abscisic,酸显示了 Desi 类型的一个更大的能力比 Kabuli 类型处理氧化应力。 | Harsh Nayyar Smita Singh Satwinder Kaur Sanjeev Kumar Hari D. Upadhyaya | 2006 | Journal of Integrative Plant Biology2006,48,11: | 6 |
| 15 | Image analysis of aggregate,mastic and air void phases for asphalt mixture显示文摘The shape characterization and spatial distribution of aggregate,mastic and air void phases for asphalt mixture were analyzed.Three air void percentage asphalt mixtures,4%,7% and 8%,respectively,were cut into cross sections and polished.X-ray scanning microscope was used to capture aggregate,mastic,air void phase by the image.The average of polygon diameter was chosen as a threshold to determine which aggregates would be retained on a given sieve.The aggregate morphological image from scanned image was utilized by digital image processing method to calculate the gradation of aggregate and simulate the real gradation.Analysis result shows that the air void of asphalt mixture has influence on the correlation between calculation gradation and actual gradation.When comparing 4.75 mm sieve size of 4%,7% and 8% air void asphalt mixtures,7% air void asphalt mixture has 55% higher than actual size gradation,8% air void asphalt mixture has 8% higher than actual size gradation,and 4% air void asphalt mixture has 3.71% lower than actual size gradation.4% air void asphalt mixture has the best correlation between calculation gradation and actual gradation comparing to other specimens.The air void percentage of asphalt mixture has no obvious influence on the air void orientation,and three asphalt mixtures show the similar air orientation along the same direction. | ADHIKARI Sanjeev YOU Zhan-ping HAO Pei-wen WANG Hai-nian | 2013 | 交通运输工程学报2013,13,2: | 6 |
| 16 | 嗜曙红血球过多: 在童年的动脉的血栓和 cardioembolic 击的稀罕原因显示文摘 Eosinophilia has been reported as a very rare cause of stroke in children.The thrombotic event may be either due to cardiac damage induced by eosinophils and their granular protein,that is,the major basic protein,or the systemic hypercoagulable state induced by eosinophilia.We report here a case of eosinophilia whose initial presentation was recurrent strokes and cardiac and arterial thrombosis. | Sanjeev Kumar Sharma Suman Kumar Tulika Seth Pravas Mishra Manoranjan Mahapatra | 2012 | World Journal of Cardiology2012,4,4: | 5 |
| 17 | 原发性眼附属器淋巴瘤的诊断及鉴别诊断显示文摘目的搜集原发性眼附属器淋巴瘤患者的影像资料,进行影像学分析,总结其影像特点,从而提高对该疾病的认识。方法回顾性分析经手术病理证实的19例原发性眼附属器淋巴瘤患者的CT及MRI特点,其中CT检查18例,MRI检查12例,同时进行CT及MRI检查者11例。结果 19例分别位于眼睑(n=10)、泪腺(n=5)、泪囊(n=3),眼外肌(n=1)。CT表现为眼附属器高密度软组织占位,CT值50~56HU,病灶无包膜,呈匍匐铸型生长,MRI呈等T1WI、等或稍长T2WI信号,增强扫描后明显强化。CT及MRI均可显示肿瘤与周围结构的关系,眼环受累(n=3),眼外肌受累(n=6)、泪腺受累(n=4),同时累及泪腺、眼环及眼外肌(n=2),以包绕为主,占位效应不明显。结论原发性眼附属器淋巴瘤较少见,临床工作中需不断总结经验,提高认识,以减少误诊。 | 苗焕民 胡粟 Sanjeev Kumar P.S 刘钊 叶爱华 | 2018 | 医学影像学杂志2018,28,7: | 5 |
| 18 | Role of advanced magnetic resonance imaging in the assessment of malignancies of the mediastinum显示文摘In the new era of functional magnetic resonance imaging(MRI), the utility of chest MRI is increasing exponentially due to several advances, including absence of ionizing radiation, excellent tissue contrast and high capability for lesion characterization and treatment monitoring. The application of several of these diagnostic weapons in a multiparametric fashion enables to better characterize thymic epithelial tumors and other mediastinal tumoral lesions, accurate assessment of the invasion of adjacent structures and detection of pathologic lymph nodes and metastasis. Also, 'do not touch lesions' could be identified with the associated impact in the management of those patients. One of the hotspots of the multiparametric chest MR is its ability to detect with acuity early response to treatment in patients with mediastinal malignant neoplasms. This has been related with higher rates of overall survival and progression free survival.Therefore, in this review we will analyze the current functional imaging techniques available(18 F-Fluorodeoxiglucose positron emission tomography/computed tomography, diffusion-weighted imaging, dynamic contrast-enhanced MRI, diffusion tensor imaging and MR spectroscopy) for the evaluation of mediastinal lesions, with a focus in their correct acquisition and post-processing. Also, to review the clinical applications of these techniques in the diagnostic approach of benign and malignant conditions of the mediastinum. | Jordi Broncano Ana María Alvarado-Benavides Sanjeev Bhalla Antonio álvarez-Kindelan Constantine A Raptis Antonio Luna | 2019 | World Journal of Radiology2019,11,3: | 4 |
| 19 | A near infrared optical reflector using one-dimensional photonic crystal structure containing chalcogenide glasses显示文摘The reflectivity of one-dimensional chalcogenide photonic crystal(CGPC) structure with the first order reflection band in near infrared(NIR) region is theoretically studied.Sb-Se and Ge-S chalcogenide glasses are used as high and low refractive index layers respectively,because these materials have zero absorption in NIR region.The transfer matrix method(TMM) is employed to calculate the reflective spectra of the proposed structure.The theoretical results of reflective spectra of bulk chalcogenide materials with the composition of Sb40Se60 and Ge30S70 for 4,8,12 and 15 layers and thicknesses of 117 nm and 183 nm respectively,at normal incidence,are close agreement with the experimental results.Furthermore,by increasing the number of layers of Sb40Se60 and Ge30S70,the reflection bands can be enhanced in the wider range of the NIR region for the polarization at different angles and thus the broadband omnidirectional reflector can be designed. | Sanjeev K.Srivastava S K Awasthi S K Srivastava S.P.Ojha | 2010 | Optoelectronics Letters2010,6,6: | 4 |
| 20 | Blockchain-Based Secured IPFS-Enable Event Storage Technique With Authentication Protocol in VANET显示文摘In recent decades,intelligent transportation systems(ITS)have improved drivers’safety and have shared information(such as traffic congestion and accidents)in a very efficient way.However,the privacy of vehicles and the security of event information is a major concern.The problem of secure sharing of event information without compromising the trusted third party(TTP)and data storage is the main issue in ITS.Blockchain technologies can resolve this problem.A work has been published on blockchain-based protocol for secure sharing of events and authentication of vehicles.This protocol addresses the issue of the safe storing of event information.However,authentication of vehicles solely depends on the cloud server.As a result,their scheme utilizes the notion of partially decentralized architecture.This paper proposes a novel decentralized architecture for the vehicular ad-hoc network(VANET)without the cloud server.This work also presents a protocol for securing event information and vehicle authentication using the blockchain mechanism.In this protocol,the registered user accesses the event information securely from the interplanetary file system(IPFS).We incorporate the IPFS,along with blockchain,to store the information in a fully distributed manner.The proposed protocol is compared with the state-of-the-art.The comparison provides desirable security at a reasonable cost.The evaluation of the proposed smart contract in terms of cost(GAS)is also discussed. | Sanjeev Kumar Dwivedi Ruhul Amin Satyanarayana Vollala | 2021 | IEEE/CAA Journal of Automatica Sinica2021,8,12: | 4 |