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| 1 | BCL-XL regulates TNF-α-mediated cell death independently of NF-κB, FLIP and IAPs显示文摘 | Raffaella Gozzelino Carme Sole Nuria Llecha Miguel F Segura Rana S Moubarak Victoria Iglesias-Guimarais M Jose Perez-Garcia Stephanie Reix Jisheng Zhang Nahuai Badiola Daniel Sanchis Jose Rodriguez-Alvarez Ramon Trullas Victor J Yuste Joan X Comella | 2008 | Cell Research2008,18,10: | 4 |
| 2 | Clinical and prognostic implications of delirium in elderly patients with non–ST-segment elevation acute coronary syndromes显示文摘Background Elderly patients with non-ST-segment elevation acute coronary syndromes(NSTE-ACS)may present delirium but its clinical relevance is unknown.This study aimed at detennining the clinical associated factors,and prognostic implications of delirium in old-aged patients admitted for NSTE-ACS.Methods LONGEVO-SCA is a prospective multicenter registry including unselected patients with NSTE-ACS aged>80 years.Clinical variables and a complete geriatric evaluation were assessed during hospitalization.The association between delirium and 6-month mortality was assessed by a Cox regression model weighted for a propensity score including the potential confounding variables.We also analysed its association with 6-month bleeding and cognitive or functional decline.Results Among 527 patients included,thirty-seven(7%)patients presented delirium during the hospitalization.Delirium was more frequent in patients with dementia or depression and in those from nursing homes(27.0%vs.3.1%,24.3%vs.11.6%,and 11.1%V5.2.2%,respectively;all P<0.05).Delirium was significantly associated with in-hospital infections(27.0%vs.5.3%,P<0.001)and usage of diuretics(70.3%vs.49.8%,P=0.02).Patients with delirium had longer hospitalizations[median 8.5(5.5-14)vs.6.0(4.0-10)days,P=0.02]and higher incidence of 6-month bleeding and mortality(32.3%vs.10.0%and 24.3%vs.10.8%,respectively;both P<0.05)but similar cognitive or functional decline.Delirium was independently associated with 6-month mortality(HR=1.47,95%CI:1.02-2.13,P=0.04)and 6-month bleeding events(OR=2.87;95%CI:1.98-4」6,P<0.01).Conclusions In-hospital delirium in elderly patients with NSTE-ACS is associated with some preventable risk factors and it is an independent predictor of 6-month mortality. | Miquel Vives-Borras Manuel Martinez-Selles Albert Ariza-Sole Maria T.Vidan Francesc Formiga Hector Bueno Juan Sanchis Oriol Alegre Albert Duran-Cambra Ramon Lopez-Palop Emad Abu-Assi Alessandro Sionis LONGEVO-SCA Investigators | 2019 | Journal of Geriatric Cardiology2019,16,2: | 3 |
| 3 | A study of loculated tuberculous pleural effusions treated with intrapleural urokinase显示文摘 | Enrique Cases Viedma María José Lorenzo Dus Andrés González-Molina José Luis Sanchis Aldás | 2006 | Respiratory Medicine2006,,11: | 2 |
| 4 | Invasive strategy in elderly patients with acute coronary syndrome in 2018: close to the truth?显示文摘Elderly population constitutes an increasingly larger proportion of patients admitted for acute coronary syndromes(ACS).The optimal management of ACS in these patients is still a challenge due to their clinical peculiarities and the paucity of specific data,and they have been traditionally managed more conservatively mainly based on subjective criteria.In ST^segment elevation acute myocardial infarction urgent reperfusion is the standard of care and there is no upper age limit.In non-ST segment elevation acute myocardial infarction evidence is controversial,incomplete and mainly focused on chronological age.While a strict conservative strategy should be avoided,routine invasive strategy may reduce the occurrence of myocardial infarction and need for revascularization at follow-up with no established benefit in terms of mortality.Clinical characteristics associated with aging,such as comorbidities and frailty,further discriminate patient's risk beyond age.Evidence is scarce,but it suggests that these features may modulate the benefit of invasive strategy in this population.Ongoing trials should clarify the optimal management of ACS based on these parameters. | Sergio García-Blas Clara Bonanad Juan Sanchis | 2019 | Journal of Geriatric Cardiology2019,16,2: | 2 |
| 5 | ST段未偏移、肌钙蛋白浓度正常的急性胸痛患者的新风险评分:与TIMI风险评分的对比研究 | Sanchis J. Bod V. Núez J. 武俊平 | 2005 | 世界核心医学期刊文摘(心脏病学分册)2005,0,12: | 2 |
| 6 | lntegrin-assist- ed drug delivery of nano-scaled polymer therapeutics bear- ing paclitaxel显示文摘 | Eldar-Boock A Miller K Sanchis J | 2011 | Biomaterials2011,32,1: | 1 |
| 7 | Wind turbines based on doubly fed induction generator under asymmetrical voltage dips显示文摘 | Lopez J Gubia E Sanchis P | | 0,,01: | 1 |
| 8 | Control of three-phase stand-alone photovoltaic systems with unbalanced loads 显示文摘 | SANCHIS P URSUA A GUBIA E | 2005 | IEEE ISIE2005,20,23: | 1 |
| 9 | Periapical surgery of 31 lower molars based on the ultrasound technique and retrograde filling with silver amalgam显示文摘 | Penarrocha Diago M Sanchis Bielsa JM Gay Escoda C | 2001 | Med Oral2001,6,5: | 1 |
| 10 | Ride through of wind turbines with doubly fed induction generator under symmetrical voltage dips 显示文摘 | Lopez J Guba E Sanchis P | 2009 | IEEE Transactions on Industrial Electronics2009,56,10: | 1 |
| 11 | Design of silicon-based slot waveguide configu - rations for optimum nonlinear performance 显示文摘 | SANCHIS P | 2007 | IEEE J Light Technol2007,25,: | 1 |
| 12 | Prognostic usefulness of white blood cell count on admission and one-year outcome in patients with non-ST-segment elevation acute chest pain显示文摘 | Sanchis J Bodi V Nunez J | 2006 | Am J Cardiol2006,98,7: | 1 |
| 13 | Characterization of the surface changes and the aging effects of low-pressure nitrogen plasma treatment in a polyurethane film 显示文摘 | SANCHIS M R CALVO O FENOLLAR O | 2008 | Polymer Testing2008,27,1: | 1 |
| 14 | Improvements in the quantitation of patulin in apple juice by high-performance liquid chromatography 显示文摘 | Rovira R Ribera F Sanchis V | 1993 | J Agric Food Chem1993,41,2: | 1 |
| 15 | Dynamic behavior of thedoubly fed induction generator during three-phasevoltage dips显示文摘 | Lopez J Sanchis P Roboa X | 2007 | IEEE Trans on Energy Conversion2007,22,3: | 1 |
| 16 | Recent advances and applications of hyperspectral imaging for fruit and vegetable quality assessment显示文摘 | LORENTE D ALEIXOS N SANCHIS J G | 2012 | Food and Bioprocess Technology2012,5,4: | 1 |
| 17 | Prognostic value of leukocytosis in acute coronary syndromes : the cinderella of the inflammatory markers 显示文摘 | Nu?ez J Nu?ez E Sanchis J | 2006 | Curr Med Chem2006,13,18: | 1 |
| 18 | Transformerless inverter for single-phase photovoltaic systems显示文摘 | Gonzalez R Lopez J Sanchis P Marroyo L | 2007 | IEEE Transaction on Power Electr onics2007,22,2: | 1 |
| 19 | Wind turbines basedon doubly fed induction generator under asymmetricalvoltage显示文摘 | Lopez J Gubia E Sanchis P | 2008 | IEEE Trans on Energy Conversion2008,23,1: | 1 |
| 20 | Wind turbines basedon doubly fed induction generator under asymmetricalvoltage dips显示文摘 | Lopez J Sanchis P Roboam X | 2008 | IEEE Trans on Energy Conversion2008,23,1: | 1 |