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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Influence of ceria on Pd activity for the CO + 02 reaction显示文摘 | GARCIA M F ARIAS A M SALAMANCA L N | 1999 | Joumal of Catalysis1999，187，2： | 1 |
| 3 | Bounds for the expected value of records from discree distributions显示文摘 | Lopez-Blazquez F Salamanca Mino B | 2006 | Journal of Statistical Planning and Inference2006，136，： | 1 |
| 4 | Bounds for the expected value of records from discree distributions显示文摘 | Lopez-Blazquez F Salamanca Mino B | 2006 | Journal of Statistical Planning and Inference2006，136，： | 1 |
| 5 | The role of the clinical research coordinator-data manager-in oncology clinical trials显示文摘 | Rico-Villademoros F Hernando T Sanz JL Lopez-Alonso A Salamanca O Camps C | 2004 | BMC Med Res Methodol2004，4，： | 1 |
| 6 | Rainfall manipulation effects on litter decomposition and the microbial biomass of the forest floor 显示文摘 | Salamanca E F Kaneko N Katagiri S | 2003 | Applied Soil Ecology2003，22，： | 1 |
| 7 | The 12p trisomy syndrome显示文摘 | Annendares S Salamanca F Nava S | 1975 | Ann Genet1975，18，2： | 1 |
| 8 | Effects of leaf litter mixtures on the decomposition of Quercus serrata and Pinus densiflora using field and laboratory microcosm methods 显示文摘 | Salamanca E F Kaneko N Katagiri S | 1998 | Ecological Engineering1998，10，1： | 1 |
| 9 | A new building energy model coupled with an urban canopy parameterization for urban climate Simulations, part I: formulation, verification, and sensitivity analysis of the model显示文摘 | SALAMANCA F KRPO A MARTILLI A | 2010 | Theoretical and applied climatology2010，99，34： | 1 |
| 10 | A numerical study of the Ur- ban Heat Island over Madrid during the DESIREX (2008) campaign with WRF and an evaluation of simple mitigation stra- tegies显示文摘 | Salamanca F Martilli A Yagiie C | 2012 | International Journal of Climatology2012，32，15： | 1 |
| 11 | Bounds for the expected value of records from discree distributions显示文摘 | Lopez-Blazquez F Salamanca Mino B | 2006 | Journal of Statistical Planning and Inference2006，136，： | 1 |
| 12 | Videoendoscopic adenoidectomy with microdebrider显示文摘 | COSTANTINI F SALAMANCA F AMAINA T | 2008 | ActaOtorhinolaryngolItal2008，28，： | 1 |
| 13 | Nematocidal activity of nitazoxanide in laboratory models显示文摘 | FONSECA- SALAMANCA F MARTINEZ- GRUEIRO M M MA- RTINEZ - FERNANDEZ A R | 2003 | Parasitol Res2003，91，4： | 1 |
| 14 | Anthropogenic heating of the urban environment due to air conditioning 显示文摘 | SALAMANCA F GEORGRSCU M MAHALOV A | 2014 | Journal of Geophysical Research-Atmos- pheres2014，119，10： | 1 |
| 15 | Rainfall manipulation effects on litter decomposition and the microbial biomass of the forest floor显示文摘 | Salamanca F Nobuhiro Kaneko | 2003 | Soil Ecology2003，3，： | 1 |
| 16 | Effects of leaf litter mixtures on the decomposition of Quercus serrata and Pinus densiflora using field and laboratory microcosm methods显示文摘 | Salamanca E F Kaneko N Katagiri S | 1998 | Ecological Engineering1998，10，1： | 1 |
| 17 | Effects of leaf lit- ter mixtures on the decomposition of Quercus serrata and Pinus densiflora using field and laboratory microcosm methods 显示文摘 | Salamanca E F Kaneko N Katagiri S | 1998 | Ecological Engineering1998，10，1： | 1 |
| 18 | Mixed leaf litter effects on decomposition rates and soil microarthropod communities in an oak-pine stand in Japan显示文摘 | Kaneko N Salamanca E F | | 0，，02： | 1 |
| 19 | C bands in human metaphase chromosomes treated by barium hydroxide显示文摘 | Salamanca F Armendares S | 1974 | Ann Genet1974，17，2： | 1 |
| 20 | 显示文摘 | Garcia F Aria M M Salamanca L N | 1999 | J Catal1999，187，2： | 1 |
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