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| 1 | Cold dialysis and its impact on renal patients' health:An evidence-based mini review显示文摘Chronic renal disease is associated with advanced age,diabetes,hypertension,obesity,musculoskeletal problems and cardiovascular disease,the latter being the main cause of mortality in patients receiving haemodialysis(HD).Cooled dialysate(35 ℃-36 ℃) is recently employed to reduce the incidence of intradialytic hypotension in patients on chronic HD.The studies to date that have evaluated cooled dialysate are limited,however,data suggest that cooled dialysate improves hemodynamic tolerability of dialysis,minimizes hypotension and exerts a protective effect over major organs including the heart and brain.The current evidence-based review is dealing with the protective effect of cold dialysis and the benefits of it in aspects affecting patients' quality of care and life.There is evidence to suggest that cold dialysis can reduce cardiovascular mortality.However,large multicentre randomized clinical trials are urgently needed to provide further supporting evidence in order to incorporate cold dialysis in routine clinical practice. | Giorgos K Sakkas Argiro A Krase Christoforos D Giannaki Christina Karatzaferi | 2017 | World Journal of Nephrology2017，6，3： | 4 |
| 2 | Restless legs syndrome is contributing to fatigue and low quality of life levels in hemodialysis patients显示文摘AIM To examine whether hemodialysis(HD) patients with restless legs syndrome(RLS) are subjects of greater fatigue and impaired quality of life(QoL) compared to HD patients without RLS.METHODS Eighty five stable HD patients participated in this study. According to their RLS status, the patients were dividedinto the RLS group(n = 23) and the non-RLS group(n = 62). QoL, fatigue, sleep quality, daily sleepiness and depression symptoms were assessed by using various questionnaires. Finally, biochemical parameters including iron, ferritin, hemoglobin, hematocrit and parathormone were assessed. RESULTS The HD patients with RLS scored worse in all the questionnaires used in the study(P < 0.05). The patients with RLS were more likely to receive the HD therapy on the morning shift, whilst 43.5% of the RLS patients reported to experience the RLS symptoms also during HD. The severity of RLS was correlated with fatigue, depression score and sleep quality(P < 0.05). CONCLUSION HD patients with RLS are subject to lower QoL related parameters and greater fatigue compared to HD patients without RLS. RLS should be successfully managed in order to improve the QoL of the sufferers. | Christoforos D Giannaki Michael Hadjigavriel Akis Lazarou Aristos Michael Loukas Damianou Efthimios Atmatzidis Ioannis Stefanidis Georgios M Hadjigeorgiou Giorgos K Sakkas Marios Pantzaris | 2017 | World Journal of Nephrology2017，6，5： | 3 |
| 3 | Nature of DNA damage in ejaculated human spermatozoa and the possi- ble involvement of apoptosis显示文摘 | SAKKAS D MOFFATT O MARIETHOZ GC | 2002 | Biol Rep rod2002，66，4： | 1 |
| 4 | Early cleavage of human embryos to the two- cell stage after intracytoplasmic sperm injection as an indicator of embryo viability显示文摘 | Sakkas D | 1998 | Hum Reprod1998，1827，： | 1 |
| 5 | Protein tyrosine phosphorylation in sperm during gamete interaction in the mouse: the influence of glucose显示文摘 | URNER F LEPPENS-LUISIER G SAKKAS D | 2001 | Biol Reprod2001，64，5： | 1 |
| 6 | Noninvasive metabolomic profiling of embryo culture media using proton nuclear magnetic resonance correlates with reproductive potential of embryos in women undergoing in vitro fertilization显示文摘 | Sell E Botros L Sakkas D | 2008 | Fertil Steril2008，，： | 1 |
| 7 | Nature of DNA damage in ejaculated human spermatozoa and the possible involvement of apoptosis显示文摘 | Sakkas D Moffatt O Manicardi GC | 2002 | Biol Reprod2002，66，4： | 1 |
| 8 | Non- pharmacological management of periodic limb movements during hemodialysis session in patients with uremic rest- less legs syndrome显示文摘 | Giannaki C D Sakkas G K Hadjigeorgiou G M | 2010 | ASAIO J2010，56，： | 1 |
| 9 | Trlfuralin photolysis in natural waters and under the presence of isolated organic matter and nitrate ions: Kinetics and photoproduct analysis显示文摘 | DIMOU A D SAKKAS V A ALBANIS T A | 2004 | Journal of Photochemistry and Photobiology A: Chemistry2004，163，： | 1 |
| 10 | Cellular maturity and apoptosis in human sperm:creatine kinase,caspase-3 and Bel-XL levels in mature and diminished maturity sperm显示文摘 | Cayli S Sakkas D Vigue L | 2004 | Mol Hum Reprod2004，10，5： | 1 |
| 11 | Photo- chemica| degradation study of Irgarol 1051 in natural waters: Influence of humic and fulvic substances on the reaction 显示文摘 | Sakkas V A Lambropoulou D A Albanis T A | 2002 | Journal of Photochemistry and Photo- biology A: Chemistry2002，147，2： | 1 |
| 12 | Sperm DNA fragmentation : mechanismsof origin,impact onreproductive outcome,and analysis 显示文摘 | Sakkas D Alvarez JG | 2010 | Fer-til Steril2010，93，4： | 1 |
| 13 | Comparison between intrathoracic blood volume and cardiac filling pressures in the early phase of hemodynamic instability of patients with sepsis or septic shock 显示文摘 | Sakka S G Bredle D L Reinhart K | 1999 | J Crit Care1999，14，2： | 1 |
| 14 | Development, glycolytic activity, viability of preimplantation mouse embryos subjected to different of glucose starvation 显示文摘 | Leppens LG Sakkas D | 1997 | Biol Reprod1997，56，： | 1 |
| 15 | Non- pharmacological management of periodic limb movements during hemodialysis session in patients with uremic rest- less legs syndrome显示文摘 | Giannaki C D Sakkas G K nadjigeorgiou G M | 2010 | ASAIO J2010，56，： | 1 |
| 16 | Up-regulation of glucose metabolism during male pronucleus formation determines the early onset of the S phase in bovine zygote显示文摘 | Comizzoli P Urner F Sakkas D | 2006 | Biol Reprod2006，68，： | 1 |
| 17 | Reduced senescence and retained nuclear DNAintegrity in human spermatozoa prepared by density gradient centrifugation 显示文摘 | Morrell JM Moffatt O Sakkas D et aI | 2004 | J Assist Reprod Genet2004，21，6： | 1 |
| 18 | Endometr-ial angiopoietin ex pression and modulation by thrombin and steroid hormones:a mech anism for abnormal angio-genesis following long-term progestin-only contraception显示文摘 | Krikun G Sakkas D Schatz F | 2004 | Am J Pathol2004，164，6： | 1 |
| 19 | Fertility testing and ICSI sperm selection by hyaluronic acid binding:clinical and genetic aspects显示文摘 | Huszar G Jakab A Sakkas D | 2007 | Reprod Biomed Online2007，14，5： | 1 |
| 20 | Protein phosphorylation in mammalian sper- matozoa显示文摘 | Umer F Sakkas D | 2003 | Reprod2003，125，： | 1 |
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