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1Proso Millet Protein Elevates Plasma Level of High-Density Lipoprotein:A New Food Function of Proso Millet显示文摘We examined the effects of dietary proso-millet protein on plasma levels of high-density lipoprotein (HDL) cholesterol in different rats from animals reported in our previous studies. The results showed also, in this animal, that the ingestion of the millet protein elevates plasma levels of HDL-cholesterol like our earlier works. Taking into account the anti-atherogenic function of HDL, therefore, the millet protein would be useful as a new food ingredient which has the function that regulates cholesterolN. NISHIZAWA S. SHIMANUKI H. FUJIHASHI H. WATANABE Y. FUDAMOTO AND T. NAGASAWA (Department of Bioscience and Technology, Faculty of Agriculture, Iwate University Morioka, Iwate 020, Japan Research Laboratory,Nitto Best Co., Ltd, Sagae, Yamagata 991 Ka 1996Biomedical and Environmental Sciences1996,9,2:24
2Endoscopic ultrasound-guided vs endoscopic retrograde cholangiopancreatography biliary drainage for obstructed distal malignant biliary strictures: A systematic review and meta-analysis显示文摘BACKGROUND For palliation of malignant biliary obstruction(MBO), the gold-standard method of biliary drainage is endoscopic retrograde cholangiopancreatography(ERCP)with the placement of metallic stents. Endoscopic ultrasound(EUS)-guided drainage is an alternative that is typically reserved for cases of ERCP failure.Recently, however, there have been robust randomized clinical trials(RCTs)comparing EUS-guided drainage and ERCP as primary approaches to MBO.AIM To compare EUS guidance and ERCP in terms of their effectiveness and safety in palliative biliary drainage for MBO.METHODS This was a systematic review and meta-analysis, in which we searched the MEDLINE, Excerpta Medica, and Cochrane Central Register of Controlled Trials databases. Only RCTs comparing EUS and ERCP for primary drainage of MBO were eligible. All of the studies selected provided data regarding the rates of technical and clinical success, as well as the duration of the procedure, adverse events, and stent patency. We assessed the risk of biases using the Jadad score and the quality of evidence using the Grading of Recommendations Assessment,Development and Evaluation criteria.RESULTS The database searches yielded 5920 records, from which we selected 3 RCTs involving a total of 222 patients(112 submitted to EUS and 110 submitted to ERCP). In the EUS and ERCP groups, the rate of technical success was 91.96%n and 91.81%, respectively, with a risk difference(RD) of 0.00%(95%CI:-0.07, 0.07;P = 0.97; I^2 = 0%). The clinical success was 84.81% and 85.53% in the EUS and ERCP groups, respectively, with an RD of-0.01%(95%CI:-0.12, 0.10; P = 0.90; I^2 =0%). The mean difference(MD) for the duration of the procedure was-0.12%(95%CI:-8.20, 7.97; P = 0.98; I^2 = 84%). In the EUS and ERCP groups, there were14 and 25 adverse events, respectively, with an RD of-0.06%(95%CI:-0.23, 0.12; P= 0.54; I^2 = 77%). The MD for stent patency was 9.32%(95%CI:-4.53, 23.18; P =0.19; I^2 = 44%). The stent dysfunction rate was significantly lower in the EUS t group(MD =-0.22%; 95 CI:-0.35,-0.08; P = 0.001; I^2 = 0%).CONCLUSION EUS represents an interesting alternative to ERCP for MBO drainage,demonstrating lower stent dysfunction rates compared with ERCP. Technical and clinical success, duration, adverse events and patency rates were similar.Fernanda P Logiudice Wanderlei M Bernardo Facundo Galetti Vitor M Sagae Carolina O Matsubayashi Antonio C Madruga Neto Vitor O Brunaldi Diogo T H de Moura Tomazo Franzini Spencer Cheng Sergio E Matuguma Eduardo G H de Moura 2019World Journal of Gastrointestinal Endoscopy2019,11,4:6
3The utility of diffusion-weighted MR imaging for differentiating uterine sarcomas from benign leiomyomas显示文摘Ken Tamai Takashi Koyama Tsuneo Saga Nobuko Morisawa Koji Fujimoto Yoshiki Mikami Kaori Togashi 2008European Radiology2008,,4:6
4Benefit of laparoscopic liver resection in high body mass index patients显示文摘AIM: To explore the impact of body mass index(BMI) on surgical outcomes in patients undergoing laparoscopic liver resection(LLR).METHODS: From January 2010 to February 2015, sixty-eight patients who underwent primary partial liver resection in our institute were retrospectively reviewed. Surgical outcomes of LLR were compared with those of open liver resection(OLR). In addition, we analyzed associations with BMI and surgical outcomes.RESULTS: Among 68 patients, thirty-nine patients underwent LLR and 29 were performed OLR. Significant difference in operation time, blood loss, and postoperative hospital stay was observed. There were no signi ficant di fferences in mortali ty and morbidity in two groups. Twenty-two patients(32.4%) were classified as obese(BMI ≥ 25). A statistically significant correlation was observed between BMI and operation time, between BMI and blood loss in OLR, but not in LLR. The operation time and blood loss of OLR were significantly higher than that of LLR in obese patients. Open liver resection and BMI were independent predictors for prolonged operation time and increased blood loss in multivariate analysis.CONCLUSION: The present study demonstrated that BMI had influenced to surgical outcomes of OLR. LLR was less influenced by BMI and had great benefit in obese patients.Hiroki Uchida Yukio Iwashita Kunihiro Saga Hiroomi Takayama Kiminori Watanabe Yuichi Endo Kazuhiro Yada Masayuki Ohta Masafumi Inomata 2016World Journal of Gastroenterology2016,22,10:4
5Outcomes of Medicare beneficiaries hospitalised with transient ischaemic attack and stratification using the ABCD^(2) score显示文摘Background Long-term outcomes for Medicare beneficiaries hospitalised with transient ischaemic attack(TIA)and role of ABCD^(2) score in identifying high-risk individuals are not studied.Methods We identified 40825 Medicare beneficiaries hospitalised from 2011 to 2014 for a TIA to a Get With The Guidelines(GWTG)-Stroke hospital and classified them using ABCD^(2)s of mortality and rehospitalisation(all-cause,ischaemic stroke,haemorrhagic stroke,myocardial infarction,and gastrointestinal and intracranial haemorrhage)for high-risk versus low-risk groups adjusted for patient and hospital characteristics.Results Of the 40825 patients,35118(86%)were high risk(ABCD^(2)≥4)and 5707(14%)were low risk(ABCD^(2)=0-3).Overall rate of mortality during 1-year follow-up after hospital discharge for the index TIA was 11.7%,44.3% were rehospitalised for any reason and 3.6%were readmitted due to stroke.Patients with ABCD^(2) score≥4 had higher mortality at 1 year than not(adjusted HR 1.18,95%CI 1.07 to 1.30).Adjusted risks for ischaemic stroke,all-cause readmission and mortality/all-cause readmission at 1 year were also significantly higher for patients with ABCD^(2) score≥4 vs 0-3.In contrast,haemorrhagic stroke,myocardial infarction,gastrointestinal bleeding and intracranial haemorrhage risk were not significantly different by ABCD^(2) score.Conclusions This study validates the use of ABCD^(2) score for long-term risk assessment after TIA in patients aged 65 years and older.Attentive efforts for community-based follow-up care after TIA are needed for ongoing prevention in Medicare beneficiaries who were hospitalised for TIA.Shreyansh Shah Li Liang Durgesh Bhandary Saga Johansson Eric E Smith Deepak L Bhatt Gregg C Fonarow Naeem D Khan Eric Peterson Janet Prvu Bettger 2021Stroke & Vascular Neurology2021,6,2:3
6Establishment and characterization of a breast cancer cell line expressing Na+/I-symporter for radioiodide concentrator gene therapy显示文摘Nakamato Y Saga T Misaki T 2000J Nucl Med2000,41,:2
7Biology of sweat glands and their disorders,II,disorders of sweat gland function显示文摘Sato K Kang WH Saga K 1989J Am Acad Dermatol1989,20,:2
8Numerical Analysis on Heat Transfer Enhancement by Waves on Falling Liquid Film显示文摘Numerical simulations have been carried out for two dimensional wavy falling liquid films on a vertical wall. The algorithm of the simulation is based on MAC method and schemes for interfacial boundary conditions are modified. Small artificial perturbations given at the inflow boundary grow rapidly and then the amplitude of the waves approaches to developed waves. Effects of the disturbance frequency on the wave development behavior and heat transfer characteristics are especially investigated. For low frequency, a disturbance wave develops to a solitary wave consisted of a large amplitude roll wave and small amplitude capillary waves. Increasing the frequency, the wave amplitude decreases and the capillary wave disappears. For further high frequency, the disturbance amplitude reduces along down stream. The heat transfer coefficient is enhanced by the surface wave and has a maximum at a certain frequency. The streamlines and the temperature contours are shown for various frequency waves and the heat transfer enhancement mechanism is clarified.Akio Miyara (Dept. of Mechanical Engineering, Saga University, Honjomachi 1, Saga-shi, Saga, 840-8502 Japan ) 2000Journal of Thermal Science2000,9,3:2
9Phase II study of S-1,docetaxeland cisplatin combination chemotherapy in patients with unresect-abale metastic gastric cancer显示文摘Satou Y Takayama T Saga T 2008Proc ASCO2008,26,:1
10In Vivo geno toxicity of heterocyclic am ines detected by a modified alkaline single cell gel electrophoresis assay in a multiple organ study in the mouse显示文摘Sasali YF Saga A 1997Mutat Res1997,395,:1
11Evaluation of primary brain tumors with FLT-PET:usefulness and limitations显示文摘Saga T Kawashima H Araki N 2006Clin Nucl Med2006,31,12:1
12Two new lanostanoids from Ganoderma lucidum 显示文摘FUJITA A ARISAWA W SAGA M 1986J Nat Prod1986,49,6:1
13Efficient multiple phase shift patterns for dense 3D acquisition in structured light scanning 显示文摘Tomislav Pribanic Saga Mrvos Joaquim Salvi 2010Image and Vision Computing2010,28,:1
14Delayed cardiac tamponade caused by self-inserted needles显示文摘Inoue T Iemura J Saga T 0,,:1
15Randomized phase IIItrial of pelvic radiotherapy versus cisplatin-based combined chem-otherapy in patients with intermediate- and high-risk endometrialcancer: a Japanese Gynecologic Oncology Group study显示文摘Susumu N Sagae S Udagawa Y 2008Gyne-col Oncol2008,108,1:1
16Design and Implementation of NAREGI SuperScheduler Based on the OGSA Architecture显示文摘NAREGI 在 2003-2007 期间是一个 5 年的日本国家格子工程,目的是其首领开发一套格子中间件用作未来电子科学的一个基础。NAREGIalso 试图在格子中间件的标准化带路,基于 OGSA 建筑学。Itssuper 调度程序基于建议 OGSA 他们建筑学,因为它成为在 OGSA-EMSarchitecture 文件 v.1.0 以内实现记录部件关系的首先工作的实现。通过在设计和实现的努力和经验,记录 OGSA 他们建筑学是相当可行的,这被证实了,但是将要求精炼和速度改进的重要数量使结束它的详细说明。Thesuper 调度程序也越过多重地点支持合作分配支持执行到对面的基于 ofgrid 的 MPI 用机器制造的自动化执行。如此的资源分配要求在没在当前的 OGSA 他们建筑学盖住的 OGSA 他们部件之间的复杂相互作用,其中一些是重要的。总的来说,工作与 OGSA 他们安排证明了不仅工作,而且那它的工作分配和执行时间在合理界限以内。Satoshi Matsuoka Masayuki Hatanaka Yasumasa Nakano Yuji Iguchi Toshio Ohno Kazushige Saga Hidemoto Nakada 2006Journal of Computer Science & Technology2006,21,4:1
17A novel homozygous Ile535Asn mutation in the rod cGMP phosphodiesterase beta-subunit gene in two brothers of a Japanese family with autosomal recessive retinitis pigmentosa显示文摘Saga M Mashima Y Akeo K 1998Curr Eye Res1998,17,3:1
18Three new lanostanoids from Ganoderma lucidum 显示文摘ARISAWA M FUJITA A SAGA M 1986J Nat Prod1986,49,4:1
19Downregula- tion of vasohibin- 2, a novel a- ngiogenesis regulator, suppresses tumor growth by inhibiting angiogenesis in end - ometrial cancer cells 显示文摘Koyanagi T Saga Y Takahashi Y 2013Oncol Lett2013,5,3:1
20Clinical value of positron emission tomography with FDG for recurrent ovarian cancer显示文摘Nakamoto Y Saga T Ishimori T 2001AJR Am J Roentgenol2001,176,:1
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