| 1 | Optimizing pulsed current gas tungsten arc welding parameters of AA6061 aluminium alloy using Hooke and Jeeves algorithm显示文摘Though the preferred welding process to weld aluminium alloy is frequently constant current gas tungsten arc welding (CCGTAW),it resulted in grain coarsening at the fusion zone and heat affected zone(HAZ).Hence,pulsed current gas tungsten arc welding(PCGTAW) was performed,to yield finer fusion zone grains,which leads to higher strength of AA6061 (Al-Mg-Si) aluminium alloy joints.In order to determine the most influential control factors which will yield minimum fusion zone grain size and maximum tensile strength of the joints,the traditional Hooke and Jeeves pattern search method was used.The experiments were carried out based on central composite design with 31 runs and an algorithm was developed to optimize the fusion zone grain size and the tensile strength of pulsed current gas tungsten arc welded AA6061 aluminium alloy joints.The results indicate that the peak current (Ip) and base current (IB) are the most significant parameters,to decide the fusion zone grain size and the tensile strength of the AA6061 aluminum alloy joints. | S.BABU T.SENTHIL KUMAR V.BALASUBRAMANIAN | 2008 | 中国有色金属学会会刊:英文版2008，18，5： | 8 |
| 3 | Identification of binding interactions between myeloperoxidase and its antibody using SERS显示文摘Surface Enhanced Raman Spectroscopy(SERS) is a widely used spectroscopic method that can dramatically increase the sensitivity of Raman spectroscopy and has demonstrated significant benefit in the identification of biological molecules. We report the use of SERS in differentiating the bound immunocomplex of myeloperoxidase(MPO) and its antibody from the unbound complex and its individual components. The SERS signal was enabled by gold nanoparticles attached to MPO, p Ab and their immunocomplex at an excitation wavelength of 785 nm. The obtained SERS spectrum of MPO is in agreement with previous literature. Comparative SERS spectrum analysis of MPO, p Ab, and their immunocomplex reveals the significant peak shifts and intensity variations caused by the conformational changes due to the immunocomplex formation. Several key areas have been identified which correspond to specific amino acids being shielded from undergoing resonance while new amino acid residues are made visible in the SERS spectrum of the immunocomplex and could be a result of conformational binding. Our work demonstrates the capability of SERS to identify binding events and differentiate an immunocomplex from its unbound components with direct applications in biosensors. | E.S.Papazoglou S.Babu S.Mohapatra D.R.Hansberry C.Patel | 2010 | Nano-Micro Letters2010，2，2： | 1 |
| 4 | Fluoride contamination in groundwater:A global review of the status,processes,challenges,and remedial measures显示文摘Groundwater pollution by fluoride is one of the prime concerns of the world population due to its toxicity,which results in adverse health impacts.In this paper,we review the current scenario of the fluoride contamination of groundwater in various countries across the globe and its impact on human health.During the last decade,several newly affected regions have been reported all over the world,with more than 100 countries affected by fluoride contamination in groundwater(concentration exceeding the acceptable limit of 1.5 mg/L defined by the World Health Organization).Fluoride poisoning is mainly due to the unsupervised ingestion of products for dental and oral hygiene and over-fluoridated drinking water.It is estimated that more than 200 million people from different countries are affected by fluoriderelated groundwater issues and health problems.The highest among these are from the countries in Africa(38),Asia(28),and Europe(24),followed by countries like South America(5),North America(3),and Australia(2).The source of fluoride in drinking water is primarily geogenic,together with forage,grasses and grains,tea,and anthropogenic sources.These countries affected were correlated with climatic zones and geological factors to gain insights into geospatial relations.Our analyses show that most of the fluoride pollution-prone zones are located in high-grade metamorphic terranes with granitoid or alkaline intrusions,geothermal hot springs,and volcanic regions with arid or semi-arid climatic conditions.This study also finds that children across the globe are more vulnerable than adults to fluoride contamination.The review finds that,although there are efficient fluoride removal techniques,including filters with next-generation nanomaterials,to date,there has not been a single technique developed that can claim to be a practically robust solution for fluoride removal from drinking water.Therefore,we suggest developing next-generation filters that can retain essential minerals in water and remove only harmful ones and selecting purification technologies according to need,climate,geology,and geographic location.The findings from our review would help policymakers take effective and sustainable measures for safe water supply in the affected areas.Within the framework of the Sustainable Development Goals(SDGs),particularly SDG 3(Good Health and Well-being)and SDG 6(Clean Water and Sanitation),this study emphasizes the critical role of fluoride as a key indicator.It underscores the imperative of addressing elevated fluoride levels in drinking water,particularly in African and Asian countries,to achieve the overarching objective of universal and equitable access to safe,affordable,and uncontaminated drinking water for global society by the targeted year of 2030. | E.Shaji K.V.Sarath M.Santosh P.K.Krishnaprasad B.K.Arya Manisha S.Babu | 2024 | Geoscience Frontiers2024，15，2： | 0 |
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