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| 1 | The Arabidopsis AP2/ERF Transcription Factor RAP2.11 Modulates Plant Response to Low-Potassium Conditions显示文摘植物对低营养素的条件作出回应通过新陈代谢并且增加他们的能力到的形态学变化幸存并且成长。抄写因素 RAP2.11 通过高亲密关系的 K+ 举起 transporter AtHAK5 的规定和低钾的信号 transduction 小径的另外的部件在对低钾的反应作为一个部件被识别。RAP2.11 通过包含了被低钾仅仅通常导致的 AtHAK5 倡导者驾驶的一个酶标记的 Arabidopsis 线标注的激活被识别。这个因素在 vitro 并且在 vivo 跳了到 AtHAK5 倡导者的 GCC 盒子。抄本介绍表明很多基因在由 RAP2.11 overexpression 的根是起来调整的。许多调整基因被识别在在 low-K+ 发信号是重要的功能的范畴。这些范畴包括了乙烯发信号,反应的氧种类生产,并且钙发信号。起来调整的基因的倡导者区域在也在 AtHAK5 倡导者包含的 GCCGGC 主题被充实。这些结果建议 RAP2.11 在 low-K+ 条件下面调整 AtHAK5 表示并且也在表明串联的 low-K+ 通过另外的基因的规定贡献协调回答到低钾的条件。 | Min Jung Kim Daniel Ruzicka Ryoung Shin Daniel P. Schachtman | 2012 | Molecular Plant2012，5，5： | 18 |
| 2 | Subcellular Localization and In Vivo Interactions of the Arabidopsis thaliana Ethylene Receptor Family Members显示文摘气体的植物激素乙烯在更高的植物调整到环境条件的许多发展过程和回答。在 Arabidopsis thaliana,发信号的乙烯感觉和开始被与原核生物的二部件的传感器 histidine kinases 有关的五受体的一个家庭调停。在烟草(Nicotiana benthamiana ) 的标注荧光的受体的短暂表示表皮的叶房间证明所有乙烯受体被指向到 ER endomembrane 网络并且不本地化到 plasmalemma。在支持在 planta 覆盖研究,乙烯受体形式 homomeric 和 heteromeric,在在生活的 ER 的蛋白质建筑群种房间,由膜招募试金出现。在 vivo 相互作用模式可比较的 A 在酵母被发现基于配偶的 split-ubiquitin 系统。重叠但是乙烯受体基因的不同表示模式在不同植物纸巾建议乙烯受体建筑群的一篇微分作文。我们的调查结果可以在乙烯上有关键功能的含意荷尔蒙感觉,发信号的正式就职,信号变细和输出的调停受体的效率。 | Christopher Grefen Katrin Stadele Kamil Ruzicka Petr Obrdlik Klaus Hatter Jakub Horak | 2008 | Molecular Plant2008，1，2： | 8 |
| 3 | Does combined therapy of curcumin and epigallocatechin gallate have a synergistic neuroprotective effect against spinal cord injury?显示文摘Systematic inflammatory response after spinal cord injury(SCI) is one of the factors leading to lesion development and a profound degree of functional loss. Anti-inflammatory compounds, such as curcumin and epigallocatechin gallate(EGCG) are known for their neuroprotective effects. In this study, we investigated the effect of combined therapy of curcumin and EGCG in a rat model of acute SCI induced by balloon compression. Immediately after SCI, rats received curcumin, EGCG, curcumin + EGCG or saline [daily intraperitoneal doses(curcumin, 6 mg/kg; EGCG 17 mg/kg)] and weekly intramuscular doses(curcumin, 60 mg/kg; EGCG 17 mg/kg)] for 28 days. Rats were evaluated using behavioral tests(the Basso, Beattie, and Bresnahan(BBB) open-field locomotor test, flat beam test). Spinal cord tissue was analyzed using histological methods(Luxol Blue-cresyl violet staining) and immunohistochemistry(anti-glial fibrillary acidic protein, anti-growth associated protein 43). Cytokine levels(interleukin-1β, interleukin-4, interleukin-2, interleukin-6, macrophage inflammatory protein 1-alpha, and RANTES) were measured using Luminex assay. Quantitative polymerase chain reaction was performed to determine the relative expression of genes(Sort1, Fgf2, Irf5, Mrc1, Olig2, Casp3, Gap43, Gfap, Vegf, NfκB, Cntf) related to regenerative processes in injured spinal cord. We found that all treatments displayed significant behavioral recovery, with no obvious synergistic effect after combined therapy of curcumin and ECGC. Curcumin and EGCG alone or in combination increased axonal sprouting, decreased glial scar formation, and altered the levels of macrophage inflammatory protein 1-alpha, interleukin-1β, interleukin-4 and interleukin-6 cytokines. These results imply that although the expected synergistic response of this combined therapy was less obvious, aspects of tissue regeneration and immune responses in severe SCI were evident. | Jiri Ruzicka Lucia Machova Urdzikova Barbora Svobodova Anubhav G. Amin Kristyna Karova Jana Dubisova Kristyna Zaviskova Sarka Kubinova Meic Schmidt Meena Jhanwar-Uniyal Pavla Jendelova | 2018 | Neural Regeneration Research2018，13，1： | 4 |
| 4 | Flow- rejection lmmunoassays: Present and future显示文摘 | POLLEMA C H RUZICKA J LERNMARK A | 1992 | Microchem J1992，45，2： | 1 |
| 5 | Sequential in- jection: a new concept for chemical n- sots, process analysis and laboratory as- says 显示文摘 | Ruzicka J Marshall G D | 1990 | Anal Chim Acta1990，237，2： | 1 |
| 6 | Multiple symmetric lipom- atosis: an unusual cause of childhood obesity and mental retarda- tion显示文摘 | Kratz C Lenard HG Ruzicka T | 2000 | Eur J Pediatr Neurol2000，4，2： | 1 |
| 7 | Leptin in person with simple obesity显示文摘 | STEJSKAL D RUZICKA V HRUBISKOVA L | 1997 | Vnitr-lek1997，43，9： | 1 |
| 8 | Central sympathoinhibitory effects of calcium channel blockers显示文摘 | Leenen FH Ruzicka M Huang BS | 2001 | Curr Hypertens Rep2001，3，4： | 1 |
| 9 | A prospective,randomized trial comparing endoscopic and surgical therapy for chronic pancreatitis显示文摘 | Dite P Ruzicka M Zboril V | 2003 | Endoscopy2003，35，7： | 1 |
| 10 | Vascular endothelial growth factor (VEGF) in the pathogenesis of psoriasis-a possible target for novel therapies? 显示文摘 | Canavese M Altruda F Ruzicka T | 2010 | J Dermatol Sci2010，58，3： | 1 |
| 11 | Effect of solids on homogeneous-heterogeneous flow regime transition in bubble cohimns 显示文摘 | Mena P C Ruzicka M C Rocha F A | 2005 | Chemical Engineering Science2005，60，22： | 1 |
| 12 | Skin levels of arachi-donic acidderived inflammatory mediators and histamine inatopic dematitis and Dsoriasis显示文摘 | Simmet T Peskar BA | 1986 | J Invest Dematol1986，86，2： | 1 |
| 13 | On Leray's self-similar solutions of the Navier-Stokes equations显示文摘 | NECAS J RUZICKA M SVERAJK V | 1996 | Acta Math1996，176，： | 1 |
| 14 | Potential future dermatological indications for tacrolimus ointment显示文摘 | Ruzicka T Assmann T Lebwohl M | 2003 | Eur J Dermatol2003，13，4： | 1 |
| 15 | The new he- matology analyzer Sysmex XE 2100:performance evaluation of a novel white blood cell differential technology显示文摘 | Ruzicka K Veitl M Thalhammer-Scherrer R | 2001 | Arch Pathol Lab Med2001，125，3： | 1 |
| 16 | Anomalous and parasitic arterial blood supply in abdomen显示文摘 | Ruzicka FF jr Rossi P Abrams RE | | 0，，02： | 1 |
| 17 | Canadian Society of Nephrology commentary on the 2012 KDIGO clinical practice guideline for the management of blood pressure in CKD显示文摘 | Ruzicka M Quinn RR McFadane P | 2014 | Am J Kidney Dis2014，63，6： | 1 |
| 18 | Injection flowing ionic selective electrode cell denmark显示文摘 | Hansen EH Ruzicka J Ghose AK | 1978 | Anal Chim Acta1978，100，： | 1 |
| 19 | Collision-induced dissociation mass spectra of glucosinolate anions 显示文摘 | Bialecki J B Ruzicka J Weisbecker C S | 2010 | J Mass Spectrom2010，45，3： | 1 |
| 20 | Organ changes induced by ergotde rivative dopamine agonist drugs:time to change treatment guidelines in Parkinson's disease显示文摘 | Roth J Ulmanova O Ruzicka E | | 0，，23： | 1 |
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