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143篇 您的检索式：作者名="Rustum"

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	题名	作者	年代	出处	被引量
1	Effects of selenomethionine on acute toxicities from concurrent chemoradiation for inoperable stage Ⅲ nonsmall cell lung cancer显示文摘AIM: To prospectively determine the safety and tolerability of oral L-selenomethionine(SLM) with concurrent chemoradiation(CCRT) for Stage Ⅲ non-small cell lung cancer(NSCLC) and estimate if the incidence and/or severity of adverse events could be reduced by its use.METHODS: Sixteen patients with stage Ⅲ NSCLC were accrued to this single arm, phase Ⅱ study. CCRT consisted of radiation given at 2 Gy per fraction for 30-33 fractions, 5 d per week with concurrent weekly Ⅳ paclitaxel 50 mg/m2 followed by carboplatin dosed at an area under the time-concentration curve of 2. SLM was dosed in a loading phase at 4800 μg twice daily for one week prior to CCRT followed by once daily dosing during treatment. RESULTS: No selenium-related toxicity was observed. Analysis revealed grade 3 or higher esophagitis in 3 of 16 patients(19%), pneumonitis in 0, leukopenia in 2(12.5%), and anemia in 1(6%); the latter two were significantly reduced when compared to the protocolstated expected rate of 35%(P = 0.045 for leukopenia, and P < 0.01 for anemia). Median overall survival was 14.9 mo and median failure-free survival was 9 mo(95%CI: 3.3-21.5).CONCLUSION: There may be some protective benefit of selenium in the setting of CCRT for inoperable NSCLC. The data suggests decreased rates of myelosuppression when compared to similarly-treated historical and contemporary controls. Further evaluation of selenium in this setting may be warranted.	Michael Mix Nithya Ramnath Jorge Gomez Charles de Groot Saju Rajan Shiva Dibaj Wei Tan Youcef Rustum Michael B Jameson Anurag K Singh	2015	World Journal of Clinical Oncology2015，6，5：	4
2	Use of spatiotemporal image correlation at 11–14 weeks’ gestation显示文摘	C. Votino T. Cos R. Abu‐Rustum S. Dahman Saidi V. Gallo O. Dobrescu H. Dessy J. Jani	2013	Ultrasound Obstet Gynecol2013，，6：	2
3	Management of cervical carcinoma di-agnosed during pregnancy 显示文摘	Eitan R Abu - Rustum NR	2003	Prim Care Update Ob/Gyns2003，10，4：	1
4	Cell cycle: molecular targets for diagnesis and therapy : tumor suppressor genes and cell cycle progression in cancer 显示文摘	Giordano A Rustum YM Wenner CE	1998	J Cell Biochem1998，70，1：	1
5	Setinel lymph node mapping for grade 1 endometrial cancer: is it the answer to the surgical staging dilemma 显示文摘	Abu -Rustum NR Khoury - Collado F Pandit - Taskar N	2009	Gyn Oneol2009，113，2：	1
6	Microwave-induced reaction sintering of NiA1204显示文摘	RAMESH D PEELAMEDU RUSTUM ROY DINESH K AGRAWAL	2002	Materials Letters2002，55，4：	1
7	Thymidylate synthase inhi- bitors in cancer therapy: direct and indirect inhibitors 显示文摘	Rustum YM Harstrick A Cao S	1997	J Clin Oncol1997，15，：	1
8	Development and validation of a RP-HPLC method for the determination of gentamicin sulfateand its related substances in a pharmaceutical cream usinga short pentafluorophenyl column and a charged aerosoldetector显示文摘	Joseph A Rustum A	2010	J Pharm Biomed Anal2010，51，3：	1
9	Metal-ceramic screw-retained implant fixed partial denture with intraoral luted framework to im- prove passive fit 显示文摘	Baig Mirza Rustum	2012	J OralImplantol2012，382，：	1
10	Thymidine and hypoxanthine protection patterns of the folic acid-enhanced synergies for combinations of trimetrexate plus a polyglutamylatable inhibitor of purine or thymidylate synthesis against human ileocecal HCT-8 cells 显示文摘	Faessel Hm Slocum Hk Rustum Yin	2003	Int J Oncol2003，23，2：	1
11	Full sintering of powdered-metal bodies in a microwave field显示文摘	Rustum Roy Dinesh Agrawal Cheng Jiping	1999	Nature1999，399，：	1
12	Fertility - sparing radical ab- dominal trachelectomy for cervical carcinoma : technique and review of the literature显示文摘	Abu - Rustum NR Sonoda Y Black D	2006	Gynecol Onco12006，103，3：	1
13	Microwave hydrothermal decomposition of chlorinated organic compounds显示文摘	Man Park Sridhar Komarneni Rustum Roy	2000	Materials Letters2000，，43：	1
14	The effects of CO2 pneumoperitoneum on the survival of women with persistent metastatic ovarian cancer 显示文摘	Abu - Rustum NR Sonoda Y Chi DS	2003	Gynecol Oncol2003，90，：	1
15	Application of a new approach for the quantitation of drug synergism to the combination ofcis-diamminedichloroplatinum and 1-beta-D-arabinofuranosylcytosine显示文摘	Park HS Rustum YM	1990	Cancer Res1990，50，17：	1
16	Thymidylate synthase: a critical target in cancer therapy显示文摘	RUSTUM YM	2004	Front Biosci2004，9，9：	1
17	Application of Lc-MSn in conjunction with mechanism-based stress studies in the elucidation of drug impurity structure:Rapid identification of a process impurity in betamethasone 1 7-valerate drug substance显示文摘	LI M LIN M X RUSTUM A	2008	J Pharm Biomed Anal2008，48，：	1
18	Clinical implications of 5-FU modulation 显示文摘	Rustum Y M	1999	Oncology (Williston Park)1999，13，73：	1
19	显示文摘	Rustum R Dinesh A Cheng Jiping	1999	Nature1999，399，：	1
20	University--Industry interaction patterns显示文摘		1972	Science New series1972，178，4064：	1

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