|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | ATP11B deficiency leads to impairment of hippocampal synaptic plasticity显示文摘Synaptic plasticity is known to regulate and support signal transduction between neurons, while synaptic dysfunction contributes to multiple neurological and other brain disorders;however, the specific mechanism underlying this process remains unclear. In the present study, abnormal neural and dendritic morphology was observed in the hippocampus following knockout of Atpllb both in vitro and in vivo. Moreover, ATP11B modified synaptic ultrastructure and promoted spine remodeling via the asymmetrical distribution of phosphatidylserine and enhancement of glutamate release, glutamate receptor expression, and intracellular Ca^2+ concentration. Fuithermoe experimental results also indicate that ATP11B regulated synaptic plasticity in hippocampal neurons through the MAPK14 signaling pathway. In conclusion, our data shed light on the possible mechanisms underlying the regulation of synaptic plasticity and lay the foundation for the exploration of proteins involved in signal transduction during this process. | Jiao Wang Weihao Li Fangfang Zhou Ruili Feng Fushuai Wang Shibo Zhang Jie Li Qian Li Yajiang Wang Jiang Xie Tieqiao Wen | 2019 | Journal of Molecular Cell Biology2019，11，8： | 2 |
| 2 | Influencing Factors of Fine Root Production and Turnover in Forest Ecosystem显示文摘Fine roots(≤2mm in diameter) play important roles in carbon balance and nutrient recycling in forest ecosystem.With the development of the study on global carbon cycle,fine roots have attracted considerable attention as the main source of soil carbon in forest ecosystem.On the basis of synthetic analysis of research reports in domestic and foreign literatures,we summarized and elaborated the major abiotic and biotic factors that control fine root production and turnover.The environmental factors included soil nutrient,soil temperature,soil moisture and the CO2 concentration.Soil organisms,fine root morphology and forest stand characteristics were discussed as biotic factors in this paper.Finally,we defined the problems arising in root system research and prospected the future research direction. | Wang Ruili Cheng Ruimei Xiao Wenfa Feng Xiaohui Liu Zebin Wang Xiaorong | 2012 | Chinese Forestry Science and Technology2012，11，3： | 2 |
| 3 | Nitrogen- doped ordered mesoporous graphitic arrays with high electro- catalytic activity for oxygen reduction 显示文摘 | LIU Ruili WU Dongqing FENG Xinliang | 2010 | Angewandte Che- mic2010，122，14： | 1 |
| 4 | Potential glioblastoma biomarkers identified by mass spectroscopy and iTRAQ labeling显示文摘Glioblastoma multiforme(GBM)is the most common primary malignant tumor of the central nervous system.Grade IV GBM is lethal,and has a high rate of relapse despite aggressive therapy.The prognosis is poor because of therapeutic resistance and tumor relapse.1 Very low rates of clinical responses and frequent treatment failures are common.Previous studies have focused on identifying genetic alterations in GBM that have diagnostic and prognostic values and may help to define the subclasses of the GBM patients,2,3 including mutations in isocitrate dehydrogenase 1(IDH1),amplification of epidermal growth factor receptors(EGFR),and mutations and polymorphisms of telomerase reverse transcriptase(TERT)promoter.These markers are useful for identifying the pathogenesis of malignant glioma formation,but they are all associated with tumorigenesis and do not currently influence the treatment of most GBM patients. | Ruili Feng Mingyu Chen Guanghong Luo Yanlu Chen Jiao Wang Jian Xu Ming Xu Ping Zhong Tieqiao Wen | 2023 | Genes & Diseases2023，10，5： | 0 |
| 5 | Effects of Different Seedling Grades on Yield and Commercial Quality of Codonopsis pilosula显示文摘[Objectives] This study was conducted to further explore the yield increasing potential of Codonopsis pilosula, and to seek seedlings suitable for efficient production of C. pilosula. [Methods] The effects of C. pilosula seedlings of different sizes on root yield and commercial quality under different cultivation densities were studied. [Results] The fourth-grade seedlings had the least input, the highest yield of 6 948 kg/hm^2, the largest output-to-input ratio at 18.3, the highest root weight proportion of the second-grade product at 58.1%, and the lowest root weight proportion of the first-grade product at 17.6%. Considering the yield, quality and economic benefits comprehensively, the treatment of the fourth-grade seedlings(seedling diameter≤4 mm) is the best choice, and the suitable plant spacing is 8 cm×22 cm. [Conclusions] The study provided a reference basis for the cost saving and efficiency improvement of C. pilosula production. | Shuxian XIAO Zhenhong LEI Chaoxia SONG Xufeng WANG Yulong WANG Yan ZHAO Zhen FENG Ruili MENG | 2020 | Agricultural Biotechnology2020，9，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员