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| 1 | Natural origin scaffolds with in situ pore forming capability for bone tissue engineering applications显示文摘 | Ana M.Martins Marina I.Santos Helena S.Azevedo Patricia B.Malafaya Rui L.Reis | | 0,,: | 1 |
| 2 | Translation of biomaterials from bench to clinic显示文摘Scientific research originates from curiosity and interests. Translational research of biomaterials should always focus on addressing specific needs of the targeted clinical applications. The guest editors of this special issue hope that the included articles have provided cutting-edge biomaterials research as well as insights of the translation of biomaterials from bench to clinic. | Kai Zhang Antonios G.Mikos Rui L.Reis Xingdong Zhang | 2022 | Bioactive Materials2022,7,12: | 1 |
| 3 | An Outlook on Implantable Biosensors for Personalized Medicine显示文摘Biosensors are a fast-growing field,as they have been shown to be very helpful in our daily life,playing roles in industries such as agriculture,food safety,homeland security,bioprocessing,environmental monitoring,and industrial monitoring.Beyond these,the application of biosensing in medicine and biomedical engineering may have the highest potential for growth and for affecting human quality of life in the near future.This potential is driven by the need for new and improved devices and technologies with improved sensitivity,specificity,reliability,and biocompatibility. | Rita Rebelo Ana Isabel Barbosa Vitor M.Correlo Rui L.Reis | 2021 | Engineering2021,7,12: | 0 |
| 4 | Properties of Collagen/Sodium Alginate Hydrogels for Bioprinting of Skin Models显示文摘3D printing technology has great potential for the reconstruction of human skin.However,the reconstructed skin has some differences from natural skin,largely because the hydrogel used does not have the appropriate biological and physical properties to allow healing and regeneration.This study examines the swelling,degradability,microstructure and biological properties of Collagen/Sodium Alginate(Col/SA)hydrogels of differing compositions for the purposes of skin printing.Increasing the content of sodium alginate causes the hydrogel to exhibit stronger mechanical and swelling properties,a faster degradation ratio,smaller pore size,and less favorable biological properties.An optimal 1%collagen hydrogel was used to print bi-layer skin in which fibroblasts and keratinocytes showed improved spreading and proliferation as compared to other developed formulations.The Col/SA hydrogels presented suitable tunability and properties to be used as a bioink for bioprinting of skin aiming at finding applications as 3D models for wound healing research. | Tian Jiao Qin Lian Weilong Lian Yonghui Wang Dichen Li Rui L.Reis Joaquim Miguel Oliveira | 2023 | Journal of Bionic Engineering2023,20,1: | 0 |
| 5 | Understanding the corrosion of Mg alloys in in vitro urinary tract conditions: A step forward towards a biodegradable metallic ureteral stent显示文摘Ureteral stents play a fundamental role in modern time urology. However, following the deployment, stent-related symptoms are frequent and affect patient health and quality of life. Using biodegradable metals as ureteral stent materials have emerged as a promising strategy, mainly due to the improved radial force and slower degradation rate expected. Therefore, this study aimed to characterize different biodegradable metals in urinary tract environment to understand their propensity for future utilization as base materials for ureteral stents. The corrosion of 5 Mg alloys - AZ31, Mg-1Zn, Mg-1Y, pure Mg, and Mg-4Ag - under simulated urinary tract conditions was accessed. The corrosion layer of the different alloys presented common elements, such as Mg(OH)_(2), MgO, and phosphate-containing products, but slight variations in their chemical compositions were detected. The corrosion rate of the different metals varied, which was expected given the differences in the corrosion layers. On top of this, the findings of this study highlighted the significant differences in the samples' corrosion and corrosion layers when in stagnant and flowing conditions. With the results of this study, we concluded that Mg-1Zn and Mg-4Ag presented a higher propensity for localized corrosion, probably due to a less protective corrosion layer;Mg-4Ag corroded faster than all the other four alloys,and Mg-1Y stood out due to its distinct corrosion pattern, that showed to be more homogeneous than all the other four samples, making this one more attractive for the future studies on biodegradable metals. | Margarida Pacheco Ivo M.Aroso Joana M.Silva Sviatlana V.Lamaka Jan Bohlen Maria Nienaber Dietmar Letzig Estêvão Lima Alexandre A.Barros Rui L.Reis | 2023 | Journal of Magnesium and Alloys2023,11,11: | 0 |