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| 1 | Survival and an overview of decision-making in patients with cholangiocarcinoma显示文摘BACKGROUND:Cholangiocarcinoma is rare,accounting for approximately 3%of all gastrointestinal cancers.This study aimed to identify the survival rate among surgically treated and palliated patients,and secondly to identify parameters that could predict a curative resection. METHODS:A total of 121 patients,55 men and 66 women, median age 70 years(range 31-91),who had been treated for cholangiocarcinoma in the period of 1990-2005 were evaluated retrospectively. RESULTS:Curative resection was performed in 40 patients (33%),whereas 81 received palliative treatment(67%).16% (19 of 121)of the patients had an explorative laparotomy without tumour resection.Age above 65 years(OR 3.4;95% CI 1.4-8.4;P=0.008),weight loss(OR 8.5;95%CI 1.5-46; P=0.01)or tumour location(The resection rate of hilar cholangiocarcinoma was lower than that of intrapancreatic cancer.)(OR 2.7;95%CI 1.7-4.5;P=0.001)predicted palliative treatment.The adjusted 5-year survival rate of patients who received tumour resection and palliative treatment was 30%and 1.2%,respectively(P<0.001).The survival rate of patients who were subjected to hepatectomy (70%)was better than that of patients who had a local or distal resection(20%)(P=0.02). CONCLUSIONS:In few patients with a resectable cholangiocarcinoma,an explorative laparotomy is often necessary to evaluate resectability.However,long-term survival is significantly better in patients who received radical surgical resection. | Hvard Mjφrud Forsmo Arild Horn Asgaut Viste Dag Hoem Kjell φvrebφ | 2008 | Hepatobiliary & Pancreatic Diseases International2008，7，4： | 6 |
| 2 | Accuracy of abdominal auscultation for bowel obstruction显示文摘AIM:To investigate the accuracy and inter-observer variation of bowel sound assessment in patients with clinically suspected bowel obstruction.METHODS:Bowel sounds were recorded in patients with suspected bowel obstruction using a Littmann® Electronic Stethoscope. The recordings were processed to yield 25-s sound sequences in random order on PCs. Observers,recruited from doctors within the department,classified the sound sequences as either normal or pathological. The reference tests for bowel obstruction were intraoperative and endoscopic findings and clinical follow up. Sensitivity and specificity were calculated for each observer and compared between junior and senior doctors. Interobserver variation was measured using the Kappa statistic.RESULTS:Bowel sound sequences from 98 patients were assessed by 53(33 junior and 20 senior) doctors. Laparotomy was performed in 47 patients,35 of whom had bowel obstruction. Two patients underwent colorectal stenting due to large bowel obstruction. The median sensitivity and specificity was 0.42(range:0.19-0.64) and 0.78(range:0.35-0.98),respectively. T h e re wa s n o s i g n i f i c a n t d i ffe re n c e i n a cc u ra c y between junior and senior doctors. The median frequency with which doctors classified bowel sounds as abnormal did not differ significantly between patients with and without bowel obstruction(26% vs 23%,P = 0.08). The 53 doctors made up 1378 unique pairs and the median Kappa value was 0.29(range:-0.15-0.66).CONCLUSION:Accuracy and inter-observer agreement was generally low. Clinical decisions in patients with possible bowel obstruction should not be based on auscultatory assessment of bowel sounds. | Birger Michael Breum Bo Rud Thomas Kirkegaard Tyge Nordentoft | 2015 | World Journal of Gastroenterology2015，21，34： | 4 |
| 3 | Towards a theory of tiered testing显示文摘 | Hansson SO Rudén C | 2007 | RegulToxicol Pharmacol2007，48，1： | 1 |
| 4 | Standardising fast -track surgical nursing care in Denmark显示文摘 | JAKOBSEN DH RUD K KEHLET H | 2014 | Br J Nurs2014，23，9： | 1 |
| 5 | Stability and motion af ter traumatic dislocation of the knee 显示文摘 | THOMSEN P B RUD B JENSEN U H | 1984 | Acta Orthop Scand1984，55，3： | 1 |
| 6 | Removal of impacted lower third molars with acute pericoronitis and necrotising gingivitis显示文摘 | Rud J | 2007 | Br Oral Surg2007，6，7： | 1 |
| 7 | Far-infrared properties of DAST显示文摘 | Markus Marther Kasper Jensby Soren Rud Keiding | 2000 | Optical Letters2000，25，12： | 1 |
| 8 | Risk to all or none Acomparative analysis of controversies in the health risk assessmentof bisphenol A显示文摘 | Beronius A Rud^n C HSkansson H | 2010 | Reprod Toxicol2010，29，2： | 1 |
| 9 | 5-ALA, but not 5-ALA-ester, is transported through the BETA transporters显示文摘 | Rud E Gederaas O Hogset A | 2000 | J Photochem Photobiol2000，71，： | 1 |
| 10 | Physical Properties of CdGeAs2 Crystals Grown by Solid-state Synthesis显示文摘 | Rud'V Yu Rud'Yu V Ushakova T N | 1999 | Semiconductors1999，33，11： | 1 |
| 11 | Genome sequence of the naturally plasmid-free Lactobacillus plantarum strain NC8 (CCUG 61730)显示文摘 | Axelsson L Rud I Naterstad K | | 0，，09： | 1 |
| 12 | Root fractures due to corrosion显示文摘 | RUD J OMNELL K A | 1970 | Scand J Dent Res1970，78，39： | 1 |
| 13 | Changes in mutagenicity during crude oil degradation by fungi 显示文摘 | RUD L E | 1996 | Biodegradation1996，7，4： | 1 |
| 14 | Compact Septum Polarizers with a Circular Output Waveguide 显示文摘 | Kirilenko A A Kulik D Yu Rud L A | 2004 | MSMW''04 Symposium Proceeding2004，2，： | 1 |
| 15 | Determinants of bone mass and bone size in a large cohort of physically active young adult men显示文摘 | Rudding JA Cosman F Zion M | 2006 | Nutr Metab2006，3，： | 1 |
| 16 | Factors maintaining the in- traurethral pressure in women 显示文摘 | Rud T Andersson KE Asmussen M | 1980 | Invest Urol1980，17，4： | 1 |
| 17 | Hydrogen storage of the Mg-C composites显示文摘 | Rud A D Lakhnik A M Ivanehenko V G | 2008 | Int J Hydrogen Energy2008，33，： | 1 |
| 18 | The drug addict and the stigma of addiction 显示文摘 | Dean JC Rud F | 1984 | Int J Addict1984，19，： | 1 |
| 19 | Are hydroelectric reservoirs significant sources of greenhouse gases显示文摘 | Rud J M Harris R Kelly C A | 1993 | Ambio1993，22，： | 1 |
| 20 | A novel multiplex quantitative DNA array based PCR (MQDA-PCR) for quantification of transgenic maize in food and feed显示文摘 | RUDI K RUD I HOLCK A | 2003 | Nucleic Acids Res2003，31，： | 1 |
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