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| 1 | Endocrine radionuclide scintigraphy with fusion single photon emission computed tomography/computed tomography显示文摘AIM: To review the benefits of single photon emission computed tomography(SPECT)/computed tomography(CT) hybrid imaging for diagnosis of various endocrine disorders.METHODS: We performed MEDLINE and Pub Med searches using the terms: 'SPECT/CT'; 'functional anatomic mapping'; 'transmission emission tomography'; 'parathyroid adenoma'; 'thyroid cancer'; 'neuroendocrine tumor'; 'adrenal'; 'pheochromocytoma'; 'paraganglioma'; in order to identify relevant articles published in English during the years 2003 to 2015. Reference lists from the articles were reviewed to identify additional pertinent articles. Retrieved manuscripts(case reports, reviews, meta-analyses and abstracts) concerning the application of SPECT/CT to endocrine imaging were analyzed to provide a descriptive synthesis of the utility of this technology.RESULTS: The emergence of hybrid SPECT/CT camera technology now allows simultaneous acquisition of combined multi-modality imaging, with seamless fusion of three-dimensional volume datasets. The usefulness of combining functional information to depict the biodistribution of radiotracers that map cellular processes of the endocrine system and tumors of endocrine origin, with anatomy derived from CT, has improved the diagnostic capability of scintigraphy for a range of disorders of endocrine gland function. The literature describes benefits of SPECT/CT for ^(99m)Tc-sestamibi parathyroid scintigraphy and ^(99m)Tc-pertechnetate thyroid scintigraphy, ^(123)I- or ^(131)I-radioiodine for staging of differentiated thyroid carcinoma, ^(111)In- and ^(99m)Tclabeled somatostatin receptor analogues for detection of neuroendocrine tumors, ^(131)I-norcholesterol(NP-59) scans for assessment of adrenal cortical hyperfunction, and ^(123)I- or ^(131)I-metaiodobenzylguanidine imaging for evaluation of pheochromocytoma and paraganglioma.CONCLUSION: SPECT/CT exploits the synergism between the functional information from radiopharmaceutical imaging and anatomy from CT, translating to improved diagnostic accuracy and meaningful impact on patient care. | Ka-Kit Wong Arpit Gandhi Benjamin L Viglianti Lorraine M Fig Domenico Rubello Milton D Gross | 2016 | World Journal of Radiology2016，8，6： | 3 |
| 2 | An ectopic mediastinal parathyroid adenoma accurately located by a single day imaging protocol of Tc-99m pertechnetate-MIBI subtraction scintigraphy and MIBI-SPECT computed tomographic image fusion显示文摘 | Rubello D Casara D Fiore D | | 0，，03： | 1 |
| 3 | Functional scintigraphy of the adrenal gland显示文摘 | Rubello D Bui C Casara D | 2002 | Eur J Endocrinol2002，147，1： | 1 |
| 4 | Role of gamma probes in performing minimally invasive parathyroidectomy in patients with primary hyperparathyroidism:optimization of preoperative and intraoperative procedures显示文摘 | Rubello D Piotto A Casara D | 2003 | Eur J Endocrind2003，149，1： | 1 |
| 5 | Sentinel lymph node (SLN) procedure with patent V blue dye in 153 patients with papillary thyroid carcinoma (PTC):is it an accurate staging method 显示文摘 | Rubello D Nanni C Merante Bosehin I | 2006 | Exp Clin Cancer Res2006，25，4： | 1 |
| 6 | ^18F-FDG PET/CT in the assessment of carcinoma of unknown primary origin显示文摘 | Ambrosini V Nanni C Rubello D | 2006 | Radiol Med2006，111，8： | 1 |
| 7 | Role of ^18F-FDG PET-CT imaging for the detection of an unknown primary tumour:preliminary results in 21 patients显示文摘 | Nanni C Rubello D Castellueei P | 2005 | Eur J Nucl Med Mol Imaging2005，32，5： | 1 |
| 8 | Chronic obstructive pulmonary disease and cardiovascular mortality in elderly subjects from general population显示文摘 | Mazza A Zamboni S Rubello D | 2010 | Blood Press2010，19，2： | 1 |
| 9 | Different fea- tures of pulmonary metastases in differentiated thyroid cancer: Natural history and multivariate statistical analy- sis of prognostic variables显示文摘 | Casara D Rubello D Saladini G | 1993 | J Nucl Med1993，34，10： | 1 |
| 10 | Different fea-tures of pulmonary metastases in differentiated thyroid cancer:nat-ural history and muhivariate statistieal analysis of prognostic varia-bles显示文摘 | CASARA D RUBELLO D SALADINI G | 1993 | J Nucl Med1993，34，10： | 1 |
| 11 | Funtional scintigraphy of the adrenal gland显示文摘 | Bui C Casara D | 2002 | Eur J Endocrinol2002，147，： | 1 |
| 12 | The role of dual-time combined 18-fluorodeoxyglucose positron emission tomography and computed tomography in the staging and restaging workup of locally advanced rectal cancer,treated with preoperative chemoradiation therapy and radical surgery显示文摘 | Capirci C Rubello D Pasini F | 2009 | Int J Radiat Oncol Biol Phys2009，74，： | 1 |
| 13 | Long-term prognostic value of 18F-FDG PET in patients with locally advanced rectal cancer previously treated with neoadjuvant radiochemotherapy显示文摘 | Capirci C Rubello D Chierichetti F | 2006 | AJR Am J Roentgenol2006，187，： | 1 |
| 14 | Funtional scintigraphy of the adrenal gland 显示文摘 | Rubello D Bui C Casara D | 2002 | Eur J Endocrinol2002，147，： | 1 |
| 15 | Non-FDG PET in the prac- tice of oncology 显示文摘 | Caroli P Nanni C Rubello D | 2010 | Indian J Cancer2010，47，2： | 1 |
| 16 | Can FDG PET/CT monitor the response to hormonal therapy in breast cancer patients?显示文摘 | Evangelista L Rubello D Saladini G | 2012 | EurJ Nucl Med Mol Imaging2012，39，3： | 1 |
| 17 | Role of gamma probes in performing minimally invasiveparathyroidectomy in patients with primary hyperparathyroidism:optimization ofpreoperative and intraoperative procedures显示文摘 | Rubello D Piotto A Casara D | 2003 | Eur J Endocrind2003，149，1： | 1 |
| 18 | 18 F-FDG PET/CT in the assessment of carcinoma of unknown primary origin显示文摘 | Ambrosini V Nanni C Rubello D | 2006 | Radiol Med2006，111，： | 1 |
| 19 | 99Tcm -MIBI radioguided minimally invasive parathyriodcctomy: expericnce with patients with normal thyroid and nodular goiters显示文摘 | Casara D Rubello D auzzoC | 2002 | Thyriod2002，12，1： | 1 |
| 20 | Usefulness of the combined antithyroglobulin antibodies and thyroglobulin assay in the follow-up of patients with differentiated thyroid cancer 显示文摘 | Rubello D Girelli ME Casara D | 1990 | J Endocrinol Invest1990，13，9： | 1 |
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