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| 1 | Epilepsy associated tumors: Review article显示文摘Long-term epilepsy associated tumors(LEAT) represent a well known cause of focal epilepsies. Glioneuronaltumors are the most frequent histological type consisting of a mixture of glial and neuronal elements and most commonly ariseing in the temporal lobe. Cortical dysplasia or other neuronal migration abnormalities often coexist. Epilepsy associated with LEAT is generally poorly controlled by antiepileptic drugs while, on the other hand, it is high responsive to surgical treatment. However the best management strategy of tumor-related focal epilepsies remains controversial representing a contemporary issues in epilepsy surgery. Temporo-mesial LEAT have a widespread epileptic networkwith complex epileptogenic mechanisms. By using an epilepsy surgery oriented strategy LEAT may have an excellent seizure outcome therefore surgical treatment should be offered early, irrespective of pharmacoresistance, avoiding both the consequences of uncontrolled seizures as well as the side effects of prolonged pharmacological therapy and the rare risk of malignant transformation. | Marco Giulioni Gianluca Marucci Matteo Martinoni Anna Federica Marliani Francesco Toni Fiorina Bartiromo Lilia Volpi Patrizia Riguzzi Francesca Bisulli Ilaria Naldi Roberto Michelucci Agostino Baruzzi Paolo Tinuper Guido Rubboli | 2014 | World Journal of Clinical Cases2014，2，11： | 9 |
| 2 | Antithrombotic management of patients on oral anticoagulation undergoing coronary artery stenting显示文摘Patients on oral anticoagulation(OAC),who are referred for coronary artery stenting account for about 5% of the whole population undergoing percutaneous coronary intervention(PCI).Although relatively small,this patient subset poses particular problems owing to the need to balance carefully the risk of bleeding against the risk of stent thrombosis and thromboembolism.Triple therapy(TT) of OAC,aspirin and clopidogrel appears as the most effective for prevention of stent thrombosis and thromboembolism.However,an increased incidence of major bleeding is to be expected during follow-up.Therefore,TT should be prolonged for as short a time as possible,and implantation of drug-eluting stents avoided.Frequent monitoring of international normalized ratio is also warranted,and the intensity of OAC should be targeted at the lower limit of the therapeutic range.Gastric protection should also be considered for all patients on medium-to long-term TT,owing to the observed highest incidence of bleeding at the gastrointestinal site.Peri-procedural management is cumbersome,and a substantial incidence of inhospital major bleeding has been reported.Since this latter is more related to procedural variables than to TT itself,choice of radial access,avoidance of glycoprotein Ⅱb/Ⅲa inhibitors,and preference for not interrupting effective OAC should be implemented.However,the evidence on which the recommendations for managing this patient subset are based is limited and of relative poor quality.While waiting for the results of ongoing,large prospective studies that are aimed at conclusively determining optimal medium-to long-term antithrombotic treatment,the official recommendations issued by the Working Group on Thrombosis of the European Society of Cardiology on the management of patients on OAC undergoing PCI with stenting should followed. | Andrea Rubboli | 2010 | World Journal of Cardiology2010，2，3： | 4 |
| 3 | Incidence, clinical impact and risk of bleeding during oral anticoagulation therapy显示文摘Bleeding is the most important complication of oral anticoagulation (OAC) with vitamin K-antagonists. Whilst bleeding is unavoidably related to OAC, it may have a great impact on the prognosis of treated subjects by leading to discontinuation of treatment, permanent disability or death. The yearly incidence of bleeding during OAC is 2%-5% for major bleeding, 0.5%-1% for fatal bleeding, and 0.2%-0.4% for intracranial bleeding. While OAC interruption and/or antagonism, as well as administration of coagulation factors, represent the necessary measures for the management of bleeding, proper stratification of the individual risk of bleeding prior to start OAC is of paramount importance. Several factors, including advanced age, female gender, poor control and higher intensity of OAC, associated diseases and medications, as well as genetic factors, have been proven to be associated with an increased risk of bleeding. Most of these factors have been included in the development of bleeding prediction scores, which should now be used by clinicians when prescribing and monitoring OAC. Owing to the many limitations of OAC, including a narrow therapeutic window, cumber-some management, and wide interand intra-individual variability, novel oral anticoagulants, such as factor Xa inhibitors and direct thrombin inhibitors, have been recently developed. These agents can be given in f ixed doses, have little interaction with foods and drugs, and do not require regular monitoring of anticoagulation. While the novel oral anticoagulants show promise for effective thromboprophylaxis in atrial f ibrillation and venous thromboembolism, def initive data on their safety and eff icacy are awaited. | Andrea Rubboli Cecilia Becattini Freek WA Verheugt | 2011 | World Journal of Cardiology2011，3，11： | 3 |
| 4 | 再谈闪光刺激方法学:新版欧洲脑电图室视觉刺激方法显示文摘间断性闪光刺激(IPS)是脑电图监测中常用的检测方法,旨在发现儿童及成人异常癫痫样放电对闪光的敏感性(即光敏感性).但在临床实践中,不同的国家以及不同的脑电图室采用的IPS方法不同,导致结果有所差异.我们认为应该建立标准的检测方法,从而能够可重复地定性和定量检测光敏感性,更利于监测和识别癫痫和光敏感性患者.与1999年发表的方法相比较,新方法不仅增加了内容,而且对IPS检测技术以及相关的操作原理进行了详述.为了提高有效性及实用性,该方法通过6年的欧洲神经病学及癫痫专家实践反馈并且反复讨论形成了共识. | Dorothee Kasteleijn-Nolst Trenite Guido Rubboli Edouard Hirsch Antonio Martins da Silva Stefano Seri Arnold Wilkins Jaime Parra Athanasios Covanis Maurizio Elia 刘永红(译) 张文娟(译) 来江(译) | 2014 | 中华神经科杂志2014，47，4： | 3 |
| 5 | Peripro- cedural and medium-term antithrombotic strate- gies in patients with an indication for long- term anticoagulation undergoing coronary angiography and intervention显示文摘 | Rubboli A Colletta M Herzfeld J | 2007 | Coron Artery Dis2007，18，3： | 1 |
| 6 | Eneephalopathy with status epilepticus during sleep (ESES) induced by oxcarbazepine in idiopathic fecal epilepsy in childhood 显示文摘 | Pavlidis E Rubboli G Nikanorova M | 2015 | Funet Neurol2015，30，2： | 1 |
| 7 | Combination of a new oral anticoagulant,aspirin and clopidogrel after acute coronary syndr ome:new therapeutic standard显示文摘 | Rubboli A Oldgren J Marìn F | 2013 | Internal and emergency medicine2013，8，8： | 1 |
| 8 | A video-polygraphic analysis of the cataplectic attack显示文摘 | Rubboli G d′Orsi G Zaniboni A | | 0，，： | 1 |
| 9 | Combination of a new o- ral anticoagulant,aspirin and clopidogrel after acute coronary syndrome:new therapeutic standard显示文摘 | Rubboli A Oldgren J Marin F | 2013 | Intern Emerg Med2013，8，8： | 1 |
| 10 | Focal epilepsy associated with dysembryoplastic neuroepithelial tumor in the area of the caudate nucleus 显示文摘 | Giulioni M Rubboli G Marucci G et ol | 2012 | Clin Neurol Neurosurg2012，114，8： | 1 |
| 11 | Overview of presurgi- cal assessment and surgical treatment of epilepsy from the Ital- ian League Against Epilepsy 显示文摘 | Guerrini R Scerrati M Rubboli G | 2013 | Epildpsia2013，54，7： | 1 |
| 12 | Antithrombotic treatment for patients on oral anticoagulation undergoing coronary stenting:a review of the available evidence and practical suggestions for the clinician显示文摘 | Rubboli A Verheugt FW | 2008 | Int J Cardiol2008，123，3： | 1 |
| 13 | Antithrombotic treatment after coronary artery stenting in patients on chronic oral anticoagulation: an international survey of current clinical practice 显示文摘 | Rubboli A Colletta M Sangiorgio P | 2004 | ltal Heart J2004，5，： | 1 |
| 14 | Peri-procedural and mediumterm antithrombotic strategies in patients with an indication for longterm anticoagulation undergoing coronary angiography and intervention 显示文摘 | Rubboli A Colletta M Herzfeld J | 2007 | Coron Artery Dis2007，18，： | 1 |
| 15 | Clinical and neurophysiologic features of progressive myoclonus epilepsy without renal failure caused by SCARB2 mutations 显示文摘 | Rubboli G Franceschetti S Berkovic SF | 2011 | Epilepsia2011，52，12： | 1 |
| 16 | EEG diagnostic procedures and speicial investigations in the assessment of photosensitivity显示文摘 | Rubboli G Parra J Seri S | 2004 | Epilepsia2004，48，1： | 1 |
| 17 | One-year outcome of patients with atrial fibrillation undergoing coronary artery stenting:an analysis of the AFCAS registry显示文摘 | RUBBOLI A SCHLITT A KIVINIEMI T | 2014 | Clin Cardiol2014，37，： | 1 |
| 18 | Differential diagno sis of pulmonary embolism in outpatients with nunspecific car- diopulmonary symptoms显示文摘 | Squizzato A Lueiani D Rubboli A | 2013 | Intern Emerg Med2013，8，8： | 1 |
| 19 | Neurophysiology ot' juvenile myoclonic epilepsy 显示文摘 | Serafini A Rubboli G Gigli GL | 2013 | Epilepsy Behav2013，28，1： | 1 |
| 20 | Meta-analysis of trials comparing oral anticoagulation and aspirin versus dual antiplatelet therapy after coronary stenting显示文摘 | Rubboli A Milandri M Castelvetri C | 2005 | Cardiology2005，104，： | 1 |
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