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| 1 | Quality of life issues in men undergoing androgen deprivation therapy: a review显示文摘雄激素剥夺治疗(ADT ) 是为治疗前列腺癌症(PCa ) 的一种必要治疗选择。为神经质的治疗的角色开始被限制为人与变形、不能实行,局部地先进的疾病。现在,它为外科和放射疗法被扩大了到 neoadjuvant 或辅助治疗,为在外科或放射以后的生物化学的恶化,并且为非变形的疾病弄平同样主要的治疗。对待的百分之五十个 PCa 病人将在某点收到 ADT。关于与更普遍的 ADT 使用联系的不利效果和费用正在种担心。生活(QoL ) 的质量上的不利效果,当人们是剥夺雄激素的时,包括物理、社会、心理的健康,可能可观。这评论在下列区域检验 QoL 问题:身体女性化,性变化,关系变化,认知、感情方面的症状,疲劳,睡觉骚乱,消沉和物理效果。推进建议因为减少这些改变的治疗学的途径被建议。 | Rowan G Casey Niall M Corcoran S Larry Goldenberg | 2012 | Asian Journal of Andrology2012，14，2： | 2 |
| 2 | Pediatric asthma severity score is associated with critical care interventions显示文摘AIM To determine if a standardized asthma severity scoring system(PASS) was associated with the time spent on continuous albuterol and length of stay in the pediatric intensive care unit(PICU).METHODS This is a single center,retrospective chart review study at a major children's hospital in an urban location.To qualify for this study,participants must have been admitted to the PICU with a diagnosis of status asthmaticus.There were a total of 188 participants between the ages of two and nineteen,excluding patients receiving antibiotics for pneumonia.PASS was calculated upon PICU admission.Subjects were put into one of three categories based on PASS: ≤ 7(mild),8-11(moderate),and ≥ 12(severe).The groups were compared based on different variables,including length of continuous albuterol and PICU stay.RESULTS The age distribution across all groups was similar.The median length of continuous albuterol was longest in the severe group with a duration of 21.5 h(11.5-27.5),compared to 15(7.75-23.75) and 10(5-15) in the moderate and mild groups,respectively(P = 0.001).Thelength of stay was longest in the severe group,with a stay of 35.6 h(22-49) compared to 26.5(17-30) and 17.6(12-29) in the moderate and mild groups,respectively(P = 0.001).CONCLUSION A higher PASS is associated with a longer time on continuous albuterol,an increased likelihood to require noninvasive ventilation,and a longer stay in the ICU.This may help safely distribute asthmatics to lower and higher levels of care in the future. | Danielle K Maue Nadia Krupp Courtney M Rowan | 2017 | World Journal of Clinical Pediatrics2017，6，1： | 2 |
| 3 | Glucocorticoid receptor and protein/RNA synthesis-dependent mechanisms underlie the control of synaptic plasticity by stress显示文摘 | Xu L Holscher C Anwyl R Rowan M J | 1998 | Proc Natl Acad USA1998，95，： | 1 |
| 4 | Determination of extractable and bound condensed tannin concentrations in forage plants, protein concentrate meals and cereal grains显示文摘 | Terrill T H Rowan A M Douglas G B | 1992 | Journal of the Science of Food and Agriculture1992，58，3： | 1 |
| 5 | E-cadherin/13- catenin complex status in solid pseudopapillary tumor of the pa- nereas显示文摘 | EI-Bahrawy M A Rowan A Homeastle D | 2008 | Am J Surg Pathol2008，32，1： | 1 |
| 6 | Identifica-tion of conjugated triene oxidation products ofα-far-nesene in apple skin显示文摘 | Rowan D D Allen J M Fiedler S | 1995 | Journal of Agricultural andFood Chemistry1995，43，8： | 1 |
| 7 | APC mutations in sporadic colorectal tumors: A mutational ' hotspot' and interdepend ence of the two hits显示文摘 | Rowan AJ Lamlum H Ilyas M | 2000 | Proc Natl Acad Sci USA2000，97，7： | 1 |
| 8 | 查看详情显示文摘 | Vriezema D M Aragonès M C Elemans J A A W Cornelissen J J L M Rowan A E Nolte R J M | | 0，，： | 1 |
| 9 | Intratumor heterogeneity and branched evolution revealed by multiregion sequencing 显示文摘 | Gerlinger M Rowan AJ Horswell S | 2012 | N Engl J Med2012，366，： | 1 |
| 10 | Block of long-term potentiation by naturally secreted and synthetic amyloid beta-peptide in hippocampal slices is mediated via activation of the kinases c-Jun-N-terminal kinase, cyclin-dependent kinase 5, and P38mitogen-activated protein kinase as well as metabotropic glutamate receptor type 5 显示文摘 | Wang Q Walsh DM Rowan M J | 2004 | J Neuresci2004，24，13： | 1 |
| 11 | High temperature reduces apple fruit colour via modulation of the anthocyanin regulatory complex显示文摘 | Wang L K Micheletti D Palmer J Volz R Lozano L Espley R Hellens R P Chagn6 D Rowan D D Troggio M Iglesias I Allan A C | 2011 | Plant Cell & Environment2011，34，： | 1 |
| 12 | The pathophysiolog- ical basis of chronic hypoxic pulmonary hypertension in the mouse:vasoconstrictor and structural mechanisms contribute equally 显示文摘 | Cahill E Rowan SC Sands M | 2012 | Exp Physiol2012，97，6： | 1 |
| 13 | Intratumor heterogeneity and branched evolution revealed by multiregion sequencing 显示文摘 | Gerlinger M Rowan AJ Horswell S | 2012 | N Engl J Med2012，366，10： | 1 |
| 14 | A new flux and stator resistance identifier for AC drive systems 显示文摘 | KERKMAN R J SEIBEL B J ROWAN T M | 1996 | IEEE Transactions on Industry Applications1996，32，3： | 1 |
| 15 | Intratumor heterogeneity and branched evolution revealed by muhiregion sequencing显示文摘 | Gerlinger M Rowan A J Homwell S | 2012 | N Engl J Med2012，366，10： | 1 |
| 16 | Analysis of folding and de- formation within layered evaporites in Blocks BM-S-8 &- 9, Santos Basin, Brazil 显示文摘 | FIDUK J C ROWAN M G | 2012 | Geological Society London Special Publications2012，363，1： | 1 |
| 17 | Relationship between ultraviolet (UV) radiation and mycosporine-like amino acids (MAAs) in marine organisms 显示文摘 | BANASZAK A T ROWAN M P KUFFNER I B | 1998 | Bulletin of Marine Science1998，63，： | 1 |
| 18 | Developmental dependence, the role of the kiilases p38 MAPK, and PKC, and the involvement of tumor necrosis factor-R1 in the induction of mGlu-5 LTD in the dentate gyrus 显示文摘 | Wang Q Chang L Rowan M J | 2007 | Neuroscience2007，144，1： | 1 |
| 19 | Biosynthesis of 2-methylbutyl,2-methyl-2-butenyl and 2-methyl butanoate esters in Red Delicious and Granny Smith apples using deuterium-labeled substrate显示文摘 | Rowan D D Lane H P Allen J M Hunt M B | 1996 | J Agric Food Chem1996，44，： | 1 |
| 20 | Salt-related faultfamilies and fault wells in the northern Gulf of Mexico 显示文摘 | Rowan M S Jackson MPA Trudgill B D | 1999 | AAPG Bulletin1999，83，9： | 1 |
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