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| 1 | Helicobacter pylori infection and endocrine disorders:Is there a link?显示文摘Helicobacter pylori(H pylori) infection is a leading world-wide infectious disease as it affects more than half of the world population and causes chronic gastritis,peptic ulcer disease and gastric malignancies.The infection elicits a chronic cellular inflammatory response in the gastric mucosa.However,the effects of this local inflammation may not be confi ned solely to the digestive tract but may spread to involve extraintestinal tissues and/or organs.Indeed,H pylori infection has been epidemiologically linked to extra-digestive conditions and diseases.In this context,it has been speculated that H pylori infection may be responsible for various endocrine disorders,such as autoimmune thyroid diseases,diabetes mellitus,dyslipidemia,obesity,osteoporosis and primary hyperparathyroidism.This is a review of the relationship between H pylori infection and these endocrine disorders. | Konstantinos X Papamichael Garyphallia Papaioannou Helen Karga Anastasios Roussos Gerassimos J Mantzaris | 2009 | World Journal of Gastroenterology2009，15，22： | 42 |
| 2 | Helicobacter pylori infection and respiratory diseases:a review显示文摘In the past few years, a variety of extradigestive disorders,including cardiovascular, skin, rheumatic and liver diseases,have been associated with Helicobacter pylori(H. pylori)infection. The activation of inflammatory mediators by H. pyloriseems to be the pathogenetic mechanism underlying theobserved associations. The present review summarizes thecurrent literature, including our own studies, concerning theassociation between H. pvloriinfection and respiratory diseases.A small number of epidemiological and serologic, case-control studies suggest that H. pyloriinfection may beassociated with the development of chronic bronchitis. Afrequent coexistence of pulmonary tuberculosis and H. pyloriinfection has also been found. Moreover, recent studies haveshown an increasedH. pyloriseroprevalence in patients withbronchiectasis and in those with lung cancer. On the otherhand, bronchial asthma seems not to be related withH. pyloriinfection.All associations between H. pyloriinfection and respiratorydiseases are primarily based on case-control studies,concerning relatively small numbers of patients. Moreover,there is a lack of studies focused on the pathogenetic linkbetween respiratory diseases and H. pylori infection.Therefore, we believe that larger studies should beundertaken to confirm the observed results and to clarifythe underlying pathogenetic mechanisms. | Anastasios Roussos Nikiforos Philippou Konstantinos I Gourgoulianis | 2003 | World Journal of Gastroenterology2003，9，1： | 19 |
| 3 | Effect of percutaneous endoscopic gastrostomy on gastroesophageal reflux in mechanically-ventilated patients显示文摘瞄准:在机械地通气的病人在胃的食道的倒流(GER ) 上调查经皮的内视镜的胃造口术(木钉) 的效果。方法:在未来的、使随机化的、控制研究有周期性或坚持的联系通风机的肺病(VAP ) 和 GER >
的 36 个病人 6% 被划分成木钉组(n = 16 ) 或非木钉组(n = 20 ) 。11 通气了没有倒流的病人(GER <
3%) 用作控制组。食道的 pH-metry 被执行由在基线“渡过”方法,在木钉以后的 2 和 7 d。病人们严格地被跟随在上面为胃的滋养的残余的半侧卧的位置和控制。结果:median (范围)的重要减少倒流从 7.8 在木钉组被观察( 6.2 - 15.6 )在到 2.7 的基线( 0 - 10.4 )在 d 上 7 post-gastrostomy ( P <
0.01 ),当倒流从 9 增加了时( 6.2 - 22 )到 10.8 ( 6.3 - 36.6 )( P <
0.01 )在非木钉组。在 GER (%) 和 nasogastric 试管的停留之间的重要关联被检测(r = 0.56, P <
0.01 ) 。结论:胃造口术什么时候与滋养的胃的残余的半侧卧的位置和缺席结合了,在通气病人减少胃的食道的倒流。 | Emmanuel E Douzinas Andreas Tsapalos Antonios Dimitrakopoulos Evanthia Diamanti-Kandarakis Alexandros D Rapidis Charis Roussos | 2006 | World Journal of Gastroenterology2006，12，1： | 15 |
| 4 | Stochastic optimization of mine production scheduling with uncertain ore/metal/waste supply显示文摘Optimization of long-term mine production scheduling in open pit mines deals with the management of cash flows, typically in the order of hundreds of millions of dollars. Conventional mine scheduling utilizes optimization methods that are not capable of accounting for inherent technical uncertainties such as uncertainty in the expected ore/metal supply from the underground, acknowledged to be the most critical factor. To integrate ore/metal uncertainty into the optimization of mine production scheduling a stochastic integer programming(SIP) formulation is tested at a copper deposit. The stochastic solution maximizes the economic value of a project and minimizes deviations from production targets in the presence of ore/metal uncertainty. Unlike the conventional approach, the SIP model accounts and manages risk in ore supply, leading to a mine production schedule with a 29% higher net present value than the schedule obtained from the conventional, industry-standard optimization approach, thus contributing to improving the management and sustainable utilization of mineral resources. | Leite Andre Dimitrakopoulos Roussos | 2014 | International Journal of Mining Science and Technology2014，24，6： | 13 |
| 5 | Prevalence of hepatitis B and C markers among refugees in Athens显示文摘AIM: To assess the prevalence of hepatitis B and C serological markers in a population of refugees living in Athens.METHODS: One hundred and thirty refugees (81 males and 49 females, mean age ±SD: 31.7±8 years) were included in the study. The hepatitis B virus surface antigen (HBsAg),the hepatitis B virus core antibody (anti-HBc) and the hepatitis C virus antibody (anti-HCV) were detected using a third-generation immunoassay.RESULTS: Twenty individuals (15.4%) were HBsAg positive and 69 (53.1%) were anti-HBc positive. The prevalence of HBsAg and anti-HBc was higher among refugees from Albania and Asia (statistical significant difference, P<0.008 and P<0.001 respectively). The prevalence of these markers was found irrelevant to age or sex. Anti-HCV was detected in the serum of 3 individuals (2.3 %). No differences among age, sex or ethnicity regarding anti-HCV prevalence were found.CONCLUSION: It can be concluded that refugees living in Athens are an immigrant population characterized by a high incidence of HBV infection. The prevalence of HBV markers is higher among refugees from Albania and Asia. It is therefore believed that the adherence to general precautions and the initiation of HBV vaccination programs will be necessary in the future, especially in these communities.Although the prevalence of HCV infection seems to be relatively low, extended epidemiological surveys are needed to provide valid results. | Anastasios Roussos Constantin Goritsas Thomas Pappas Maria Spanaki Panagiota Papadaki Angeliki Ferti | 2003 | World Journal of Gastroenterology2003，9，5： | 11 |
| 6 | 肥胖对全髋置换术后假体周围骨溶解影响的5年和10年随访观察显示文摘背景:全髋关节置换术后最主要的远期并发症是假体周围的骨溶解。相当多的接受关节置换术的患者为体型肥胖者。目前认为,导致骨溶解的危险因素包括患者的活动、植入物的类型以及固定质量等。但关于肥胖因素对骨溶解的影响鲜见相关文献报道,而且颇受争议。本文的目的是评估肥胖对全髋关节骨水泥型假体柄置换术后5年和10年骨溶解的危险因素;其次是对临床结果及患者的满意度作出评价。方法:我们对1996至2003午期间行第三代骨水泥型假体柄全髋关节置换术的患者进行前瞻性研究。所有患者均于术后5年或10年进行随访观察,获取X线、体重指数(BMI:〈25kg/m^2=正常,25~29.9kg/m^2=超重,≥30kg/m^2=肥胖)资料以及髋关节活动度情况。对活动度的评估采用洛杉矶加利福尼亚大学(UCLA)评分方法予以评定。临床结果采用Harris髋关节评分系统和Merled’Aubign6和Postel评分系统进行分析。结果:本文对433例患者中503髋关节置换术进行研究,其中241髋(47.9%)于术后5年,262髋(52.1%)于术后10年进行评估。181髋正常体重患者中的24髋(13.3%)、205髋超重患者中的11髋(5.4%)以及117髋肥胖患者中的9髋(7.7%)发生了骨溶解,共44髋。正常体重患者髋关节活动度最高【平均UCLA活动评分(±标准差)为(5.5+2.0)分];肥胖患者评分最低[平均UCLA活动评分为(5.0±1.7)分]。当调整了活动度、骨水泥质量、患者年龄和性别因素后,肥胖患者发生骨溶解的概率并不比超重患者高(调整比值比为1.4,95%置信区间为0.6-3.7),而发现正常体重患者发生股骨骨溶解的风险明显高于超重患者(调整比值比为2.6,95%置信区间为1.2-5.7)。各组之间临床结果没有显著性差异。结论:我们发现肥胖患者在行骨水泥型股骨柄全髋置换术后5年和10年后,假体周围骨溶解的风险并未增加;而正常体重患者骨溶解的发生率反而最高。 | Anne Lubbeke Guido Garavaglia Christophe Barea Constantinos Roussos 俞鹏飞(译) 姜宏(译) | 2010 | 中华骨科杂志2010，30，12： | 4 |
| 7 | 多囊卵巢综合征妇女血浆metastin水平与胰岛素抵抗及游离雄激素水平呈负相关显示文摘Objective:This study was designed to:1 measure,for the first time,metastin (kisspeptin) levels in women with polycystic ovary syndrome (PCOS),a condition associated with hypersecretion of LH and hyperandrogenemia; and 2 investigate the possible correlations between metastin and PCOS-related reproductive and metabolic disturbances. Design:Clinical study. Setting:University hospital. Patient(s):Twenty-eight obese and overweight (body mass index BMI > 25 kg/m2) women with PCOS,28 normal weight (BMI < 25 kg/m2) women with the syndrome,and 13 obese and overweight controls (ovulatory women without clinical or biochemical hyperandrogenemia)-were selected. Intervention(s):Blood samples were collected between day 3 and day 6 of a spontaneous bleeding episode in the PCOS groups and a menstrual cycle of the controls,at 9:00 AM,after an overnight fast. Main Outcome Measure(s):Circulating levels of LH,FSH,PRL,T,Δ4-androstenedione (A),DHEAS,17α-OH-P,sex hormone-binding globulin (SHBG),insulin,glucose,and metastin were measured. Result(s):Both normal weight women with PCOS and obese controls were less insulin resistant and had significantly higher metastin levels,compared to obese and overweight women with the syndrome. Plasma kisspeptin levels were negatively correlated with BMI,free androgen index,and indices of insulin resistance. Conclusion(s):These results indicate that metastin is negatively associated with free androgen levels. The PCOS-associated insulin resistance and consequent hyperinsulinemia probably contribute to this effect by 1 stimulating androgen synthesis by the polycystic ovary (PCO) and 2 suppressing SHBG production in the liver. | Panidis D. Rousso D. Koliakos G. A. Kourtis 李跃萍 | 2006 | 世界核心医学期刊文摘(妇产科学分册)2006，0，12： | 2 |
| 8 | Quantification and assessment of fault uncertainty and risk using stochastic conditional simulations显示文摘The effect of geological uncertainty on the development and mining of underground coal deposits is a key issue for longwall mining, as the presence of faults generates substantial monetary losses. This paper develops a method for the conditional simulation of fault systems and uses the method to quantify and assess fault uncertainty. The method is based on the statistical modelling of fault attributes and the simulation of the locations of the centres of the fault traces. Fault locations are generated from the thinning of a Poisson process using a spatially correlated probability field. The proposed algorithm for simulating fault traces takes into account soft data such as geological interpretations and geomechanical data. The simulations generate realisations of fault populations that reproduce observed faults, honour the statistics of the fault attributes, and respect the constraints of soft data, providing the means to thereby model and assess the related fault uncertainty. | LI Shuxing Roussos Dimitrakopulos | 2002 | Journal of Coal Science & Engineering(China)2002，8，2： | 2 |
| 9 | Helicobacter pylori seroprevalence in patients with chronic obstructive pulmonary disease显示文摘 | Anastasios Roussos Nikiforos Philippou Vasiliki Krietsepi Evgenia Anastasakou Dionissia Alepopoulou Panagiotis Koursarakos Irineos Iliopoulos Konstantinos Gourgoulianis | 2004 | Respiratory Medicine2004，，3： | 2 |
| 10 | Toxoplasmosis snapshots: Global status of Toxoplasma gondii seroprevalence and implications for pregnancy and congenital toxoplasmosis显示文摘 | Georgios Pappas Nikos Roussos Matthew E. Falagas | 2009 | International Journal for Parasitology2009，，12： | 2 |
| 11 | STIR magnetic resonance imaging:a noninvasive method for detection and follow-up of dermatomyositis显示文摘 | Yosipovitch G Beniaminov O Rousso I | 1999 | Arch Dermatol1999，135，6： | 1 |
| 12 | Viscous heating of fluid dampers II: large-amplitude motions显示文摘 | MAKRIS N ROUSSOS Y WHITTAKER A | 1998 | Journal of Engineering Mechanics1998，124，12： | 1 |
| 13 | Development of abionematicide with Paecilomyces lilacinus to control Meloid-ogyne incognita 显示文摘 | Brand D Roussos S Pndey A | 2004 | Applied Biochemistry and Biotechnolo-gy2004，118，1： | 1 |
| 14 | Helieobacter pylori sero- prevalence in patients with chronic obstructive pulmonary disease 显示文摘 | Roussos A Philippou N Krietsepi V | 2005 | Rcsp Meal2005，99，： | 1 |
| 15 | Mosai?cing on adaptive manifolds显示文摘 | PELEG S ROUSSO B RAV-ACHA A | 2000 | IEEE Trans on Pattern Analysis and Machine Intelligence2000，22，10： | 1 |
| 16 | Water and water activity in the solid state fermentation of cassava starch by Aspergillus niger显示文摘 | Oriol E Raimbault M Roussos S | 1988 | Appl Microbiol Biotechnol1988，27，： | 1 |
| 17 | Revision total hip arthroplasty in patients 80 years or older显示文摘 | Lubbeke A Roussos C Barea C | 2012 | J Arthroplasty2012，27，6： | 1 |
| 18 | Central precocious puberty due to hypothalamic hamartoma in a 7-month-old infant girl显示文摘 | IR HR Rousso Kourti Papandreou | 2008 | Eur J Pediatr2008，167，5： | 1 |
| 19 | Diet, physical exer- cise and Orlistat administration increase serum anti-Miillerian hor- motxe (AMID levels in women with polycystic ovary syndrome (PCOS) 显示文摘 | Vosnakis C Georgopoulos NA Rousso D | 2013 | Gynecol Endocrinol2013，29，3： | 1 |
| 20 | Respiratory failure 显示文摘 | Roussos C Koutsoukou A | 2003 | Eur Respir J2003，，： | 1 |
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