|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Preprocessing of 2-Dimensional Gel Electrophoresis Images Applied to Proteomic Analysis: A Review显示文摘Various methods and specialized software programs are available for processing twodimensional gel electrophoresis(2-DGE)images.However,due to the anomalies present in these images,a reliable,automated,and highly reproducible system for 2-DGE image analysis has still not been achieved.The most common anomalies found in 2-DGE images include vertical and horizontal streaking,fuzzy spots,and background noise,which greatly complicate computational analysis.In this paper,we review the preprocessing techniques applied to 2-DGE images for noise reduction,intensity normalization,and background correction.We also present a quantitative comparison of non-linear?ltering techniques applied to synthetic gel images,through analyzing the performance of the?lters under speci?c conditions.Synthetic proteins were modeled into a two-dimensional Gaussian distribution with adjustable parameters for changing the size,intensity,and degradation.Three types of noise were added to the images:Gaussian,Rayleigh,and exponential,with signal-to-noise ratios(SNRs)ranging 8–20 decibels(d B).We compared the performanceof wavelet,contourlet,total variation(TV),and wavelet-total variation(WTTV)techniques using parameters SNR and spot ef?ciency.In terms of spot ef?ciency,contourlet and TV were more sensitive to noise than wavelet and WTTV.Wavelet worked the best for images with SNR ranging 10–20 d B,whereas WTTV performed better with high noise levels.Wavelet also presented the best performance with any level of Gaussian noise and low levels(20–14 d B)of Rayleigh and exponential noise in terms of SNR.Finally,the performance of the non-linear?ltering techniques was evaluated using a real 2-DGE image with previously identi?ed proteins marked.Wavelet achieved the best detection rate for the real image. | Manuel Mauricio Goez Maria Constanza Torres-Madronero Sarah Rothlisberger Edilson Delgado-Trejos | 2018 | Genomics, Proteomics & Bioinformatics2018，16，1： | 5 |
| 2 | Aspects of penaeid biology and ecology of relevance to aquaculture: a review 显示文摘 | Rothlisberg P C | 1996 | Aquaculture1996，164，： | 1 |
| 3 | Homozygous nonsense mutation in WNTIOB and sporadic split-hand/foot malformation (SHFM) with autosomal recessive iuheritance 显示文摘 | Blattner A Huber AR Rothlisberger B | 2010 | Am I Med Genet A2010，152，8： | 1 |
| 4 | The biology of the Penaeidae显示文摘 | Dall W Hill B J Rothlisberg P C | 1990 | Mar Biol1990，27，： | 1 |
| 5 | Restocking and stock enhancement of marine invertebrate fisheries显示文摘 | Bell J D Rothlisberg P C Munro J L | 2005 | Adv Mar Biol2005，49，： | 1 |
| 6 | Intermediates in the hydrodesulfurization of 4,6-dimethyl-dibenzothiophene over Pd/gamma-Al2O3显示文摘 | Rothlisberger A Prins R | | 0，，01： | 1 |
| 7 | Water pressure in intra- and subglacial channels 显示文摘 | Rothlisberger H | 1972 | Journal of Glaciology1972，11，62： | 1 |
| 8 | Nitrate in Greenland and Antarctic ice cores:A detailed description of post-depositional processes 显示文摘 | Rothlisberger R Hutterli M A Wolff E W | 2002 | Annals of Glaciology2002，35，1： | 1 |
| 9 | The biology of tte Peze- oidea显示文摘 | DALL W HILL B J ROTHLISBERG P C | 1990 | Mar Bio1990，27，： | 1 |
| 10 | The uplift of Un- teraargletscher at the beginning of the melt season-a conse- quence of water storage at the bed显示文摘 | Iken A Rothlisberger H Flotron A etal | 1983 | Journal of Glaciology1983，29，101： | 1 |
| 11 | New paradigm in molecular engineering of sensitizers for solar cell applications显示文摘 | Bessho T Yoneda E Yum J H Guglielmi M Tavemelli I Imai H Rothlisberger U Nazeeruddin M K Gr(a)tzel M | | 0，，16： | 1 |
| 12 | Optimization of Effective Atom Centered Potentials for London Dispersion Forces in Density Functional Theory显示文摘 | von Lilienfeld O A Tavernelli I Rothlisberger U | 2004 | Physical Review Letters2004，93，15： | 1 |
| 13 | Factors controlling nitrate in ice cores:Evidence from the Dome C deep ice core 显示文摘 | Rothlisberger R Hutterli M A Sommer S | 2000 | Journal of Geophysical Research2000，105，20： | 1 |
| 14 | Intermediates in the hydrodesulfurizationof 4,6-dimethyl-dibenzothiophene over Pd/gamma-Al2O3显示文摘 | Rothlisberger A Prins R | 2005 | J Catal2005，235，1： | 1 |
| 15 | Molecular screen ing for alkane hydroxylase genes in Gramnegative and Gram- positive strains显示文摘 | Smits T H Rothlisberger M Witholt B | 1999 | Environmental Microbiology1999，1，4： | 1 |
| 16 | The biology of the Penaidae显示文摘 | Dall W Hill B J Rothlisberg P C | 1990 | Adv Mar Biol1990，27，： | 1 |
| 17 | Water pressure in intra- and sub- glacial channels 显示文摘 | Rothlisberger H | 1972 | Journal of Glaciology1972，11，： | 1 |
| 18 | Hydrodesulfurization of 4,6-dimethyldibenzothiophene and dibenzothiophene over a- lumina supported Pt, Pd, and Pt Pd catalysts显示文摘 | Niquille Rothlisberger A Prins R | 2006 | J Catal2006，242，1： | 1 |
| 19 | Hydrodesulfurization of 4,6-dimethyldibenzothiophene over Pt, Pd, and Pt Pd cata lysts supported on amorphous silica-alumina显示文摘 | Niquille- Rothlisberger A Prins R | 2007 | Catal Today2007，123，14： | 1 |
| 20 | Water pressure in intra and subglacial channels显示文摘 | Rothlisberger H | 1972 | Journal of Glaciology1972，11，62： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员