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70篇 您的检索式:作者名="Rothel"
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1Recuperation of severe tumoral calcinosis in a dialysis patient: A case report显示文摘BACKGROUND One of the common late sequela in patients with end-stage renal disease(ESRD)is the calcium phosphate disorder leading to chronic hypercalcemia and hyperphosphatemia causing the precipitation of calcium salt in soft tissues.Tumoral calcinosis is an extremely rare clinical manifestation of cyst-like soft tissue deposits in different periarticular regions in patients with ESRD and is characterized by extensive calcium salt containing space-consuming painful lesions.The treatment of ESRD patients with tumoral calcinosis manifestation involves an increase in or switching of renal replacement therapy regimes and the adjustment of oral medication with the goal of improved hypercalcemia and hyperphosphatemia.CASE SUMMARY We describe a 40-year-old woman with ESRD secondary to IgA-nephritis and severe bilateral manifestation of tumoral calcinosis associated with hypercalcemia,hyperphosphatemia and tertiary hyperparathyroidism.The patient was on continuous ambulatory peritoneal dialysis and treatment with vitamin D analogues.After switching her to a daily hemodialysis schedule and adjusting the medical treatment,the patient experienced a significant dissolution of her soft tissue calcifications within a couple of weeks.Complete remission was achieved 11 mo after the initial diagnosis.CONCLUSION Reduced patient compliance and subsequent insufficiency of dialysis regime quality contribute to the aggravation of calcium phosphate disorder in a patient with ESRD leading to the manifestation of tumoral calcinosis.However,the improvement of the treatment strategy and reinforcement of patient compliance enabled complete remission of this rare disease entity.Lukas Westermann Lisa K Isbell Marie K Breitenfeldt Frederic Arnold Elvira Rothele Johanna Schneider Eugen Widmeier 2019World Journal of Clinical Cases2019,7,23:2
2Host-protective fragments and antibody binding epitope of the Taenia ovis 45W recombinant antigen显示文摘Lightowlers MW Waterkeyn JG Rothel JS 0,,10:1
3The gamma-interferon assay for diagnosis of bovine tuberculosis in cattle:conditions affecting the production of gamma-interferon in whole blood culture显示文摘Rothel JS1 Jones SL Corner LA 1992Aust Vet J1992,69,1:1
4Host-protective fragments and antibody binding epitopes of the Taenia ovis 45W recombinant antigen显示文摘LIGHTOWLERS M W WATERKEYN J G ROTHEL J S 1996Parasite Immunol1996,18,10:1
5Sequential nucleic acid and recombinant adenovirus vaccination induces hostprotective immune responses against Taenia ovis infection in sheep显示文摘Rothel JS Boyle DB Both GW 0,,05:1
6Cellular and humorsl immune responses of cattle to purified Mycobacterium bovis antigens显示文摘Fifis T Corner L A Rothel J S 1994Stand J Immunol1994,39,3:1
7Sequential nucleic acid and recombinant adenovirus vaccination induces host-protective immune responses against Taenia ovis infection in sheep显示文摘Rothel J S Boyle D B Both G W 1997Parasite Immunol1997,19,:1
8Immune responses associated with protection in sheep vaccinated with a recombinant antigen from Taenia ovis显示文摘Rothel JS Lightowlers MW Seow HF 1996Parasite Immunol1996,18,4:1
9Urea/DTT solubilization of a recombinant Taenia ovis antigen, 45W, expressed asa GST fusion protein results in enhanced protective immune response to the 45W moiety 显示文摘Rothel JS Wood PR Seow HF 1997Vaccine1997,15,5:1
10Cellular and humoral immuneresponses of catOe to purified Mycobacterium boris antigens 显示文摘Fifis T Comer L A Rothel J S 1994Stand J Immunol1994,39,:1
11The molecular cloning of ovine interleukin gene by the polymerase chain reaction 显示文摘Scow H F Rothel J S Radford A J 1990Nucl Acids Res1990,18,:1
12The molecular cloning of ovine interleukin gene by the polymerase chain reaction 显示文摘Seow H F Rothel J S Radford A J 1990Nucl Acids Res1990,18,:1
13Cellular and humoral immuneresponses of cattle to purified Mycobacterium boris antigens显示文摘Fifis T Corner L A Rothel J S 1994Scand J Immunol1994,39,:1
14Host-protective fragments and antibody binding epitopes of the Taenia ovis 45W recombinant antigen显示文摘Lightowler MW Waterkeyn JG Rothel JS 1996Parasite Immunol1996,18,:1
15Immune responses associated with protection in sheep vaccinated with recombinant antigen from Taenia ovis显示文摘Rothel JS Lightowlers MW Seow HF 1996Parasite Immunol1996,18,:1
16Expression, biological activity and kinetics of production of recombinant ovine TNF-a 显示文摘Scow H F Rothel J S Pepin M 1995Vet Immunol Immunopathol1995,44,:1
17Cloning and sequencing of the cDNA for ovine granulocyte-macro- phage colony-stimulating factor (GM-CSF) 显示文摘OBrien P M Rothel J S Seow H F 1991Immunol Cell Biol1991,69,1:1
18A sandwich en- zyme immunoassay for bovine interferon-gamma and its use for the detection or tuberculosis in cattle显示文摘Rothel J S Jones S L Corner L A 1990Aust Vet J1990,67,13:1
19Urea/DTT solubilization of a recombinant Taenia ovis antigen, 45W, expressed as a GST fusion protein results in enhanced protective immune response to the 45W moiety 显示文摘Rothel JS Wood PR Seow HF 1997Vaccine1997,15,5:1
20The use of recombinant ovine IL-lbeta and TNF-alpha as natural adjuvants and their physiological effects in vivo显示文摘Rothel J S Seow H F Lightowlers M W 1998Immunol Cell Biol1998,76,2:1
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