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62篇 您的检索式:作者名="Ross SC"
    题名 作者 年代 出处 被引量
1The modulation of co-stimulatory molecules by circulating exosomes in primary biliary cirrhosis显示文摘Exosomes 是 endocytic 起源的 nanoparticles,由由他们调制 cell-to-cell 通讯的能力的优点正在吸引增加的注意的无数房间人口藏匿了。他们也在许多免疫学的问题正在吸引注意,包括 autoimmunity 和,特别地调整 cytokine 和 chemokine 激活的他们的能力。主要胆汁的肝硬化(PBC ) 被认为一个模型自体免疫疾病,它对胆汁的上皮的房间有高度集中的细胞毒素的回答。我们与 PBC 和 30 健康控制(HC ) 从 29 个病人从血浆孤立 exosomes,并且用一个前 vivo 系统在 mononuclear 房间人口在 co-stimulatory 分子表示和 cytokine 生产上学习了这些 exosomes 的效果。我们也与 HC exosomes 相比在 PBC 识别了 microRNA (miRNA ) 人口。我们此处报导尽管 exosomes 不改变 cytokine 生产,他们显著地确实在介绍抗原的人口上改变 co-stimulatory 分子表示。进一步,我们在 CD14 + 单核白血球上表明了那 CD86 起来调整的表情,而在 CD11c + 上起来调整的 CD40 由从有 PBC 的病人的 exosomes 的树枝状的房间。另外,有在有 PBC 的病人的传播 exosomes 的 miRNA 表示的差别。这些数据基于 co-stimulatory 分子玩的观察有重要重要性在 T 房间激活的规定的一个微分角色。我们的观察显示从 PBC 的异常 exosomes 有选择地在介绍抗原的房间的不同子集导致 co-stimulatory 分子的表示。这些改变可以在自体免疫的肝疾病的致病包含。Takashi Tomiyama Guo-Xiang Yang Ming Zhao Weici Zhang Hajime Tanaka Jing Wang Patrick SC Leung Kazuiclli Okazaki Xiao-Song He Qianjin Lu Ross L Coppel Christopher L Bowlus M Eric Gershwin 2017Cellular & Molecular Immunology2017,14,3:18
2Congenital cytomegalov- irus (CMV) infection as a cause of permanent bilateral hearing loss: a quantitative assessment 显示文摘Grosse SD Ross DS Dollard SC 2008J Clin Virol2008,41,2:1
3New estimates of the prevalence of neurological and sensory sequelae and mortality associated with congenital cytomegalovirus infection显示文摘Dollard SC Grosse SD Ross DS 2007Rev Med Virol2007,17,5:1
4Randomised controlled trial of brief intervention with biofeedback and hypnotherapy in patients with refractory irritable bowel syndrome 显示文摘Dobbin A Dobbin J Ross SC 2013J R Coll Physicians Edinb2013,43,1:1
5Rescue angioplasty after failed thrombolysis: Technical and clinical outcomes in a large thrombolysis trial显示文摘Ross AM Lundergan CF Rohrbeck SC 1998J Am Coll Cardiol1998,31,7:1
6Congenital cytomegalovirus(CMV) infection as a cause of permanent bilateral hearing loss: aqu- antitative assessment显示文摘Grosse SD Ross DS Dollard SC 2008J Clin Virol2008,41,2:1
7Antinuclear antibody staining only centrioles in a patient with scleroderms显示文摘OsbornTG Patel NJ Ross SC 1982NEngl J Med1982,307,4:1
8The effect of dosage cards on compliance with directly observed therapy in hospital 显示文摘Sonnenberg P Ross MH Shearer SC 1998Int J Tuberc Lung Dis1998,2,2:1
9New estimates of the prev- alence of neurological and sensory sequelae and mortality as-sociated with congenital cytomegalovirus infection 显示文摘Dollard SC Grosse SD Ross DS 2007Rev Med Virol2007,17,5:1
10The effect of dosage cards on compliance with directly observed therapy in hospital显示文摘Sonnenberg P Ross MH Shearer SC 1998Int J Tubere Lung Dis1998,2,2:1
11New estimates of the prevalence ofneurological and sensory sequelae and mortality associated with con-genital cytomegalovirus infection显示文摘Dollard SC Grosse SD Ross DS 2007Rev Med Viro12007,17,5:1
12Comparison of ampicillin-sulbactam and ticarcillin-clavulanic acid in patients with chronic renal failure:effects of differential pharmacokinetics on serum bactericidal activity显示文摘Hardin TC Butler SC Ross S 1994Pharmacotherapy1994,14,2:1
13GAP-43 augments G protein-coupled receptor transduction in Xenopus laevis oocytes 显示文摘Strittmatter SM Cannon SC Ross EM 1993Proc Natl Acad Sci U S A1993,90,:1
14The value of computed scans in patients with low - risk head injuries 显示文摘Stein SC Ross SE 1990Neurosurgery1990,26,4:1
15Comparison of radiohaloanalogues of meta-iodobenzylguanidine (MIBG) for a combined gene and targeted radiotherapy approach to bladder carcinoma显示文摘Fullerton NE Boyd M Ross SC 2005Med Chem2005,1,6:1
16New estimates of the prevalence of neurological and sensory sequelae and mortality associated with congenital eytomegalovirus infeetion显示文摘Dollardl SC Grosse SD Ross DS 2007Rev Med Virol2007,17,5:1
17Comparison of radiohaloanalogues of meta-iodobenzylguanidine (MIBG) for a combined gene-and targeted radiotherapy approach to bladder carcinoma显示文摘Fullerton NE Boyd M Ross SC 2005Med Chem2005,1,6:1
18New estimates of the prevalence of neurological and sensory sequelae and mortality associated with congenital cytomegalovirus infection显示文摘Dollard SC Grosse SD Ross DS 2007Rev Med Virol2007,17,5:1
19The value of computed scans in patients with low-risk head injuries显示文摘Stein SC Ross SE 1990Neurosurgery1990,26,4:1
20New estimates of the prevalence of neurological and sensory sequelae and mor- tality associated with congenital cytomegalovirus infection 显示文摘Dollard SC Grosse SD Ross DS 2007Rev Med Virol2007,,5:1
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