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| 1 | The alternative of CubeSat-based advanced infrared and microwave sounders for high impact weather forecasting显示文摘近年来,小卫星技术的发展给传统气象卫星提供了经济有效的替补方案。本文针对可能出现的传统气象卫星的缺失情形,借助快速的区域观测系统模拟试验,探索了利用小卫星填补空缺的可能性。研究表明,单个小卫星,无论是近红外高光谱还是微波探测仪,都能够对局地强风暴天气的预报有所改进。然而,为了填补传统卫星缺失带来的影响,需要发射三颗甚至更多的小卫星来增加观测的覆盖面,以弥补小卫星精度略低、通道略少的缺陷。 | LI Zhenglong LI Jun SCHMIT Timothy J. WANG Pei LIM Agnes LI Jinlong NAGLE Fredrick W. BAI Wenguang OTKIN Jason A. ATLAS Robert HOFFMAN Ross N. BOUKABARA Sid-Ahmed ZHU Tong BLACKWELL William J. PAGANO Thomas S. | 2019 | Atmospheric and Oceanic Science Letters2019，12，2： | 3 |
| 2 | Value-added Impact of Geostationary Hyperspectral Infrared Sounders on Local Severe Storm Forecasts——via a Quick Regional OSSE显示文摘Accurate atmospheric temperature and moisture information with high temporal/spatial resolutions are two of the key parameters needed in regional numerical weather prediction(NWP) models to reliably predict high-impact weather events such as local severe storms(LSSs). High spectral resolution or hyperspectral infrared(HIR) sounders from geostationary orbit(GEO) provide an unprecedented source of near time-continuous, three-dimensional information on the dynamic and thermodynamic atmospheric fields—an important benefit for nowcasting and NWP-based forecasting. In order to demonstrate the value of GEO HIR sounder radiances on LSS forecasts, a quick regional OSSE(Observing System Simulation Experiment)framework has been developed, including high-resolution nature run generation, synthetic observation simulation and validation, and impact study on LSS forecasts. Results show that, on top of the existing LEO(low earth orbit) sounders, a GEO HIR sounder may provide value-added impact [a reduction of 3.56% in normalized root-mean-square difference(RMSD)] on LSS forecasts due to large spatial coverage and high temporal resolution, even though the data are assimilated every 6 h with a thinning of 60 km. Additionally, more frequent assimilations and smaller thinning distances allow more observations to be assimilated, and may further increase the positive impact from a GEO HIR sounder. On the other hand, with denser and more frequent observations assimilated, it becomes more difficult to handle the spatial error correlation in observations and gravity waves due to the limitations of current assimilation and forecast systems(such as a static background error covariance). The peak reduction of 4.6% in normalized RMSD is found when observations are assimilated every 3 h with a thinning distance of 30 km. | Zhenglong LI Jun LI Pei WANG Agnes LIM Jinlong LI Timothy J.SCHMIT Robert ATLAS Sid-Ahmed BOUKABARA Ross N.HOFFMAN | 2018 | Advances in Atmospheric Sciences2018，35，10： | 3 |
| 3 | The transport of chemical components in homogeneous snowpacks on Urumqi Glacier No.1, eastern Tianshan Mountains, Central Asia显示文摘Chemical records from alpine ice cores provide an invaluable source of paleoclimatic and environmental information. Not only the atmospheric chemical composition but also depositional and post-depositional processes are recorded within snow/firn strata. To interpret the environmental and climatic significance of ice core records, we studied the variability of glacier snowpack chemistry by investigating homogeneous snowpacks from October 2003 to September 2006 on Urumqi Glacier No. 1 in eastern Tianshan Mountains, Central Asia. Principle Component Analysis of ionic species in dry and wet seasons revealed the impact of meltwater in redistributing ions in the snowpacks. The 1st, 2nd and 3rd principle components for dry seasons differ significantly, reflecting complex associations between depositional or/and post-depositional processes. The variability trend of ionic concentrations during the wet seasons was found to fit a Gauss Function with significant parameters. The elution factor revealed that more than half of ions are leached out during the wet seasons. Differences with respect to ion snowpack mobility were found. Of the ions studied SO42– was the most mobile and Mg2+ the least mobile. A threshold relationship between air temperatures and the elution process was investigated over the study period. The results indicate that the strong melt /ablation processes and iconic redistribution occur at a threshold air temperature of 0°C. The study found that surface melt on the snowpacks is the main factor causing the alteration of the snowpack chemistry. Rainfall also has an impact on the chemistry but plays a less significant role than the surface melt. | YOU Xiaoni LI Zhongqin Ross EDWARDS WANG Lixia | 2015 | Journal of Arid Land2015，7，5： | 3 |
| 4 | Threshold for neural tube defect risk by accumulated singleton loss-of-function variants显示文摘 | Zhongzhong Chen Yunping Lei Yufang Zheng Vanessa Aguiar-Pulido M. Elizabeth Ross Rui Peng Li Jin Ting Zhang Richard H. Finnell Hongyan Wang | 2018 | Cell Research2018，28，10： | 3 |
| 5 | The interplay of drivers and deterrents of opportunism in buyer–supplier relationships显示文摘 | Qiong Wang Julie Juan Li William T. Ross Christopher W. Craighead | 2013 | Journal of the Academy of Marketing Science2013，，1： | 2 |
| 6 | Origin, Evolution, and Genotyping of Emergent Porcine Epidemic Diarrhea Virus Strains in the United States显示文摘 | Yao-Wei Huang Allan W. Dickerman Pablo Pi?eyro Long Li Li Fang Ross Kiehne Tanja Opriessnig Xiang-Jin Meng | 2013 | mBio2013，，5： | 2 |
| 7 | Hemorheological abnormalities in lipoprotein lipase deficient mice with severe hypertriglyceridemia显示文摘 | Tieqiang Zhao Jun Guo Hui Li Wei Huang Xunde Xian Colin J.D. Ross Michael R. Hayden Zongyao Wen George Liu | 2006 | Biochemical and Biophysical Research Communications2006，，4： | 2 |
| 8 | Levels of circulating follicular helper T cells,T helper 1 cells,and the prognostic significance of soluble form of CD40 ligand on survival in patients with alcoholic cirrhosis显示文摘Background:Excessive drinkers(ED)and patients with alcoholic liver disease(ALD)are several times more susceptible to bacterial and viral infections and have a decrease in antibody responses to vaccinations.Follicular helper T(TFH)cells are essential to select B cells in the germinal center and to produce antibodies.TFH cells express both a membrane-associated and a soluble form of CD40 ligand(sCD40L),in which the latter form is released to circulation upon T cell activation.The effect of alcohol on TFH cells has not been studied.Objectives:The goals of this study are to determine the levels of TFH and T helper 1(Th1)cells in ED and those with alcoholic cirrhosis(AC)when compared to healthy controls and to determine the prognostic significance of sCD40L in a cohort of patients with AC.Methods:Controls,ED,and those with AC were enrolled.Baseline demographic,laboratory tests,and peripheral blood mononuclear cells(PBMCs)were isolated and assessed via flow cytometry for TFH cells.In vitro study was performed to determine the ability of PBMCs to secrete interferon(IFN)-ɣupon stimulation.Serum sCD40L was also determined and its prognostic significance was tested in a cohort of AC patients.Results:The levels of circulating TFH(cTFH)cells were significantly lower in peripheral blood of subjects with ED and AC compared to controls(P<0.05).IFN-ɣsecretion from PBMCs upon stimulation was also lower in ED and those with cirrhosis.Serum sCD40L was significantly lower in ED and AC when compared to that in controls(P<0.0005).Its level was an independent predictor of mortality.Conclusions:Patients with AC had significantly lower level of cTFH and sCD40L.The level of sCD40L was an independent predictor of mortality in these patients. | Kristin Hollister Praveen Kusumanchi Ruth Ann Ross Kristina Chandler AdePeju Oshodi Laura Heathers Sean Teagarden Li Wang Alexander L.Dent Suthat Liangpunsakul | 2018 | Liver Research2018，2，1： | 2 |
| 9 | Human-animal interactions and bat coronavirus spillover potential among rural residents in Southern China显示文摘Human interaction with animals has been implicated as a primary risk factor for several high impact zoonoses,including many bat-origin viral diseases.However the animal-to-human spillover events that lead to emerging diseases are rarely observed or clinically examined,and the link between specific interactions and spillover risk is poorly understood.To investigate this phenomenon,we conducted biological-behavioral surveillance among rural residents in Yunnan,Guangxi,and Guangdong districts of Southern China,where we have identified a number of SARS-related coronaviruses in bats.Serum samples were tested for four bat-borne coronaviruses using newly developed enzyme-linked immunosorbent assays(ELISA).Survey data were used to characterize associations between human-animal contact and bat coronavirus spillover risk.A total of 1,596 residents were enrolled in the study from 2015 to 2017.Nine participants(0.6%)tested positive for bat coronaviruses.265(17%)participants reported severe acute respiratory infections(SARI)and/or influenza-like illness(ILI)symptoms in the past year,which were associated with poultry,carnivore,rodent/shrew,or bat contact,with variability by family income and district of residence.This study provides serological evidence of bat coronavirus spillover in rural communities in Southern China.The low seroprevalence observed in this study suggests that bat coronavirus spillover is a rare event.Nonetheless,this study highlights associations between human-animal interaction and zoonotic spillover risk.These findings can be used to support targeted biological behavioral surveillance in high-risk geographic areas in order to reduce the risk of zoonotic disease emergence. | Li Hongying Mendelsohn Emma Zong Chen Zhang Wei Hagan Emily Wang Ning Li Shiyue Yan Hong Huang Huimin Zhu Guangjian Ross Noam Chmura Aleksei Terry Philip Fielder Mark Miller Maureen Shi Zhengli Daszak Peter | 2019 | Biosafety and Health2019，1，2： | 2 |
| 10 | Ferromagnetism in Fe - doped Ba6Ge25 chiral clathrate显示文摘 | Yang Li Joseph H Ross Jr | 2003 | Applied Physics Letters2003，83，14： | 1 |
| 11 | Schistosomiasis in the People 's Republic of China: prospects and challenges for the 21st century显示文摘 | Ross AG Sleigh AC Li Y | 2001 | Clin Microbiol Rev2001，14，2： | 1 |
| 12 | Schistosomiasis in the People's Republic of China:prospects and challenges for the 21st century显示文摘 | Ross AG Sleigh AC Li Y | 2001 | Clin Microbiol Rev2001，14，2： | 1 |
| 13 | Can intemet video-on-demand be profitable?显示文摘 | Huang C Li J Ross K | 2007 | SIGCOMM Comput Commun Rev2007，37，4： | 1 |
| 14 | Fetal hypothalamic neuroprogenitor cell culture: preferential differentiation paths induced by leptin and insulin显示文摘 | Desai M Li T Ross MG | 2011 | Endo- crinology2011，152，8： | 1 |
| 15 | Evidence that IgE receptor stimulation increases adenosine release from rat basophilic leukaemia (RBL-2H3) cells显示文摘 | Lloyd HG Ross L Li KM | 1998 | Pulm Pharmacol Ther1998，11，1： | 1 |
| 16 | Hormone receptor stares, tu- mor characteristics,and prognosis: a prospective cohort of breast cancer patients显示文摘 | Dunnwald LK Rossing MA Li CI | 2007 | Breast Cancer Res2007，9，1： | 1 |
| 17 | The Interplay of Drivers and Deterrents of Opportunism in Buyer- Supplier relationships显示文摘 | WANG Q LI J J ROSS W T | 2012 | Journal of the Academy of Marketing Science2012，41，1： | 1 |
| 18 | Testing the reliability of genetic methods of species identification via simulation显示文摘 | Ross H A Murugan S Li W L | 2008 | Syst Biol2008，57，2： | 1 |
| 19 | Fibrinolytic therapy in hospitals without percutaneous coronary intervention capabilities in China from 2001 to 2011: China PEACE-retrospective AMI study 显示文摘 | Li J Li X Ross JS | 2016 | Eur Heart J Acute Cardiovasc Care2016，34，5： | 1 |
| 20 | Circulating lung cancer tumor cells isolated by the EpCAM-independent enrichment strategy correlate with Cytokeratin 19-derived CYFRA21-1 and pathological staging显示文摘 | Qian Chen Feng Ge Wei Cui Fei Wang Zhuo Yang Ye Guo Longyun Li Ross Macrae Bremner Peter Ping Lin | 2013 | Clinica Chimica Acta2013，，： | 1 |
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