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| 1 | An ORF2 protein-based ELISA for porcine circovirus type 2 antibodies in post-weaning multisystemic wasting syndrome显示文摘 | Ph Blanchard D Mahé R Cariolet C Truong M Le Dimna C Arnauld N Rose E Eveno E Albina F Madec A Jestin | 2003 | Veterinary Microbiology2003，，3： | 2 |
| 2 | Beneficial effects of adenosine triphosphate-sensitive K^+ channel opener on liver ischemia/reperfusion injury显示文摘AIM:To investigate the effect of diazoxide administration on liver ischemia/reperfusion injury.METHODS:Wistar male rats underwent partial liver ischemia performed by clamping the pedicle from the medium and left anterior lateral segments for 1 h under mechanical ventilation.They were divided into 3 groups:Control Group,rats submitted to liver manipulation,Saline Group,rats received saline,and Diazoxide Group,rats received intravenous injection diazoxide(3.5 mg/kg) 15 min before liver reperfusion.4 h and 24 h after reperfusion,blood was collected for determination of aspartate transaminase(AST),alanine transaminase(ALT),tumor necrosis factor(TNF-α),interleukin-6(IL-6),interleukin-10(IL-10),nitrite/nitrate,creatinine and tumor growth factor-β1(TGF-β1).Liver tissues were assembled for mitochondrial oxidation and phosphorylation,malondialdehyde(MDA) content,and histologic analysis.Pulmonary vascular permeability and myeloperoxidase(MPO) were also determined.RESULTS:Four hours after reperfusion the diazoxide group presented with significant reduction of AST(2009 ± 257 U/L vs 3523 ± 424 U/L,P = 0.005); ALT(1794 ± 295 U/L vs 3316 ± 413 U/L,P = 0.005); TNF-α(17 ± 9 pg/mL vs 152 ± 43 pg/mL,P = 0.013; IL-6(62 ± 18 pg/mL vs 281 ± 92 pg/mL); IL-10(40 ± 9 pg/mL vs 78 ± 10 pg/mL P = 0.03),and nitrite/nitrate(3.8 ± 0.9 μmol/L vs 10.2 ± 2.4 μmol/L,P = 0.025) when compared to the saline group.A significant reduction in liver mitochondrial dysfunction was observed in the diazoxide group compared to the saline group(P < 0.05).No differences in liver MDA content,serum creatinine,pulmonary vascular permeability and MPO activity were observed between groups.Twenty four hours after reperfusion the diazoxide group showed a reduction of AST(495 ± 78 U/L vs 978 ± 192 U/L,P = 0.032); ALT(335 ± 59 U/L vs 742 ± 182 U/L,P = 0.048),and TGF-β1(11 ± 1 ng/mL vs 17 ± 0.5 ng/mL,P = 0.004) serum levels when compared to the saline group.The control group did not present alterations when compared to the diazoxide and saline groups.CONCLUSION:Diazoxide maintains liver mitochondrial function,increases liver tolerance to ischemia/reperfusion injury,and reduces the systemic inflammatory response.These effects require further evaluation for using in a clinical setting. | Mateus Antunes Nogueira Ana Maria Mendona Coelho Sandra Nassa Sampietre Rosely Antunes Patzina Fabiano Pinheiro da Silva Luiz Augusto Carneiro D'Albuquerque Marcel Cerqueira Cesar Machado | 2014 | World Journal of Gastroenterology2014，20，41： | 2 |
| 3 | Reflected Blast Wave Resultants Behind Cantilever Walls:A New Prediction Technique 显示文摘 | CHAPMAN T C ROSE T A SMITHS P D | 1995 | International Journal of Impact Engineering1995，16，3： | 1 |
| 4 | An in vitro method for detecting infectious Cryptosporidium oocysts with cell culture 显示文摘 | Slifko TR Freidman D Rose JB | 1997 | Appl Environ Microbiol1997，63，9： | 1 |
| 5 | Three tomato genes code for heat stress transcription factors with a region of remarkable homology to the DNA-binding domain of the yeast HSF 显示文摘 | SCHARF K D ROSE S ZOTT W | 1990 | The EMBO Journal1990，9，13： | 1 |
| 6 | Total bilirubin is a useful predictor of persisting common bile duct stone in gallstone pancreatitis 显示文摘 | Chan T Yaghoubian A Rosing D | 2008 | Am Surg2008，74，10： | 1 |
| 7 | Anterior cruciate ligamenl radiofrequency thermal shrinkage:As hort-term follow-up显示文摘 | Famg E Hunt S A Rose D J | 2005 | Arthroscopy2005，21，9： | 1 |
| 8 | Synthesis of New Macrocyclic Bispidinone Ionophores显示文摘 | Black D S C Horsham M A Rose M | 1995 | Tetrahedron1995，51，16： | 1 |
| 9 | Facade failure effects on blast propagation along city streets显示文摘 | SMITH P D ROSE T A KRAHE S L | 2003 | Structures and Buildings2003，156，4： | 1 |
| 10 | Autoimmune myoearditis : cellular mediators of cardiac dysfunction显示文摘 | Afanasyeva M Georgakopoulos D Rose NR | 2004 | Autoimmunity Rev2004，3，78： | 1 |
| 11 | Three tomato genes code for heat stress transeription factors with a region of remarkable ho- mology to the DNA-binding domain of the yeast HSF 显示文摘 | Seharf K D Rose S Zott W | 1990 | EMBO J1990，9，： | 1 |
| 12 | Long-term moni- toring shows hepatitis B virus resistance to entecavir in nude- oside-na ve patients is rare through 5 years of therapy显示文摘 | Tenney D J Rose R E Baldick C J | 2009 | Hepatology2009，49，5： | 1 |
| 13 | CloudSim:a toolkit for modeling and simulation of cloud computing environments and evaluation of resource provisioning algorithms显示文摘 | Calheiros R N Ranjan R Rose CAF D | 2011 | Software:Practice and Experience2011，41，1： | 1 |
| 14 | Efficient stated choice experiments for estimating Nested Logit models显示文摘 | Bliemer M Rose J Hensher D A | 2009 | Transportation Research part B2009，43，1： | 1 |
| 15 | Credit Cards as Lifestyle Facilitators 显示文摘 | BERNTHAL M J CROCKETT D ROSE R L | 2005 | The Journal of Consumer Research2005，32，1： | 1 |
| 16 | Radiation curing of hybrid polymer coatings 显示文摘 | Rose K Vangeneugden D Paulussen S | 2006 | Surface Coatings International part B : Coatings Transactions2006，89，1： | 1 |
| 17 | Soluble and transmembrane isoforms of novel interleukin-17 receptor-like protein by RNA splicing and expression in prostate cancer显示文摘 | Haudenschild D Moseley T Rose L | 2002 | J Biol Chem2002，277，6： | 1 |
| 18 | Rituximab: mechanism of action and resistance 显示文摘 | Maloney D G Smith B Rose A | 2002 | Semin Oncol2002，29，12： | 1 |
| 19 | Blast wave propagation in city streets -an overview显示文摘 | Peter D Smith Timothy A Rose | 2006 | Structural Safety and Reliability2006，，8： | 1 |
| 20 | Dry drainage: a sustainable solution to waterlogging and salinity problems in irrigation areas?显示文摘 | Konukcu F Gowing J W Rose D A | 2006 | Agricultural water management2006，，83： | 1 |
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