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| 1 | Th1/Th2 cytokines and their genotypes as predictors of hepatitis B virus related hepatocellular carcinoma显示文摘Hepatocellular carcinoma(HCC), the predominant type of primary liver cancer, is one of the most serious lifethreatening malignancies, worldwide. In majority of the cases, HCC develops after prolonged and persistent chronic liver disease. hepatitis B virus(HBV) or HCV infection is prominent etiological factors, attributing to this condition. It has been well documented that HBV, being the inducer of chronic inflammation, is the main causative agent in causing HCC, particularly in Asian countries. The HBV infection leads to a wide range of clinical symptoms from carrier state to malignancy. Cytokines being immune-modulatory molecules, are the key mediators in the defense mechanism against viral infection. In this regard, this review will detail the substantial role of key Th1: interleukin 1(IL-1), IL-2, IL-12, tumor necrosis factor-α, interferon-γ; Th2: IL-4, IL-10 and non Th1/Th2: IL-6, transforming growth factor-β1 cytokines genotypes in analyzing the variability in the clinical manifestations in an HBV-afflicted individual, which might finally, culminates into HCC. Since cytokine production is regulated genetically, the cytokine promoter region single-nucleotide polymorphisms induced changes, greatly affects the cytokine production, thus resulting into differential outcome of immune balance. | Roli Saxena Jyotdeep Kaur | 2015 | World Journal of Hepatology2015，7，11： | 50 |
| 2 | 碘乙酰胺诱导的大鼠胃炎中神经肽免疫阳性神经纤维的变化显示文摘目的:探讨含不同神经肽的神经纤维在碘乙酰胺诱导的大鼠胃炎中的变化,分析神经纤维与免疫细胞的相互关系。方法:采用碘乙酰胺诱导制备大鼠胃炎模型,以纯净水喂养为对照组,采用免疫组织化学法、免疫细胞化学法定量分析对照组及模型组大鼠胃黏膜中含P物质(SP)、神经肽Y(NPY)及血管活性肠肽(VIP)的神经纤维数量及免疫活性细胞。结果:光学显微镜观察模型组和对照组胃黏膜含SP、NPY及VIP神经纤维分布于黏膜层腺体之间。模型组黏膜含SP及VIP的神经纤维数量较对照组明显增加(P<0.05)。模型组大鼠的胃黏膜可见免疫活性细胞,主要为淋巴细胞、浆细胞和肥大细胞,表明SP、NPY表现出免疫活性,免疫细胞与神经纤维毗邻。结论:胃炎模型制作成功;神经肽参与了胃炎的形成过程及免疫调节。 | 陈丽萍 吴山力 Fehēr Erzsēbet Altdorfer Károly 迟宝荣 | 2007 | 吉林大学学报(医学版)2007，33，1： | 5 |
| 3 | Dynamical Criticality:Overview and Open Questions显示文摘展出复杂行为的系统经常处于一个特别动态条件被发现,在顺序和混乱之间平衡。这观察在所谓的 criticality 假设的核心,它声明在在顺序和混乱之间的动态政体的系统达到计算能力的高水平并且完成在坚韧性和灵活性之间的一宗最佳的交易。在细胞、进化的生物学,神经科学和计算机科学的最近的结果有 revitalised 对 criticality 假设的兴趣, emphasising 它的角色作为在适应复杂系统的一条可行候选人将军法律。这份报纸在就我们为 criticality 假设特别地相关的知识而言的动态 criticality 上提供工作的概述。作者在混乱的边有关动力学和信息处理考察主要贡献,并且在生物系统在批评动力学的学习说明主要成就。最后,作者讨论待研究的问题并且为未来工作建议一个议程。 | ROLI Andrea VILLANI Marco FILISETTI Alessandro SERRA Roberto | 2018 | Journal of Systems Science & Complexity2018，31，3： | 2 |
| 4 | Black locust(Robinia pseudoacacia L.)as a multi-purpose tree species in Hungary and Romania:a review显示文摘Black locust(Robinia pseudoacacia L.) was the first North-American tree species imported to Europe at the beginning of the seventeenth century. It is commonly planted worldwide because of its adaptability to environmental stresses, its valuable wood, easy propagation, frequent and abundant seed production, excellent coppicing,high seedling survival, and relatively high wood yield. In Europe, Romania and Hungary have the most highly-developed black locust growing techniques and experiences.As a result of increasing interest in black locust in many countries, this review aims to provide a comprehensive overview of state-of-the-art site requirements, propagation, improvement and management(including growth and yield as well as use in energy plantations). | Valeriu-Norocel Nicolescu Cornelia Hernea Beatrix Bakti Zsolt Keseru Borbála Antal Károly Rédei | 2018 | Journal of Forestry Research2018，29，6： | 2 |
| 5 | Fingerprint verification by fusion of optical and capacitive sensors 显示文摘 | MARCIALIS G L ROLI F | 2004 | Pattern Recognition Letters2004，25，11： | 1 |
| 6 | Interstitial cells of Cajal in the human normal urinary bladder and in the bladder of patients with megacystis-microcolon intestinal hypoperistalsis syndrome显示文摘 | Piaseczna Piotrowska A Rolie U SolariV | 2004 | BJU Int2004，94，1： | 1 |
| 7 | Alarm clustering for intrusion detection systems in computer networks显示文摘 | Roberto Perdisci Giorgio Giacinto Fabio Roli | 2006 | Engineering Applications of Artificial Intelligence2006，19，4： | 1 |
| 8 | Dynamic classifier selection based on multiple classifier behavior显示文摘 | Giacinto G Roli F | 2001 | Pattern Recognition2001，34，9： | 1 |
| 9 | Genetic algorithms for the traveling salesman problem based on a heuristic crossover operation显示文摘 | Károly F. Pál | 1993 | Biological Cybernetics (-)1993，，5： | 1 |
| 10 | Metaheuristics in combinatorial optimization:overview and conceptual comparison显示文摘 | Blum C Roli A | 2003 | ACM Computing Surveys2003，35，3： | 1 |
| 11 | Safety and efficacy of infliximab and adalimtunab for refractory uveitis in juvenile idiopathic arthritis: 1-year fol- lowup data from the Italian Registry 显示文摘 | Zannin ME Birolo C Gerloni VM Miserocchi E Pontikaki I Pa- roli MP | 2013 | J Rheumatol2013，40，1： | 1 |
| 12 | Fusion of multiple classifiers for intrusion detection in computer networks显示文摘 | Giacinto G Roli F Didaci L | | 0，，12： | 1 |
| 13 | Metaheuristics in combinatorial optimization: overview and conceptual comparison 显示文摘 | BLUM C ROLI A | 2003 | ACM Computing Surveys2003，35，3： | 1 |
| 14 | Design of effective neural network ensembles for image classification purposes显示文摘 | Giacinto G Roli F | 2001 | Image and Vision Computing2001，19，910： | 1 |
| 15 | Fusion of multiple classifiers for intrusion detection in computer networks显示文摘 | Giacinto G Roli F Didaci L | 2003 | Pattern Recognition Letters2003，24，12： | 1 |
| 16 | Two components of the receptor current are developed from distinct elementary signals in Limulus ventral nerve photoreceptor显示文摘 | Károly Nagy Klaus Contzen Hennig Stieve | 1993 | European Biophysics Journal1993，，5： | 1 |
| 17 | Alarm clustering for intrusion detection systems in computer networks显示文摘 | Roberto Perdisci Giorgio Giacinto Fabio Roli | 2006 | Engineering Applications of Artificial Intelligence2006，，4： | 1 |
| 18 | Alarm clusteringfor intrusion detection systems in computer networks显示文摘 | Roberto Perdisci Giorgio Giacinto Fabio Roli | 2006 | Engineer-ing Applications of Artificial Intelligence2006，19，4： | 1 |
| 19 | Metaheuristics in combinatorial optimization: overview and conceptual comparison 显示文摘 | Blum C Roli A | 2003 | ACM Surveys2003，35，3： | 1 |
| 20 | Spam filtering based on the analysis of text information embedded into images显示文摘 | Fumera G Pillai I Roli F | | 0，，07： | 1 |
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